Protein Alignment Ugt37A3 and UGT2B15

DIOPT Version :9

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001067.2
• Gene: UGT2B15 / 7366
• HGNCID: 12546
• Length: 530
• Species: Homo sapiens
• Alignment Length: 547
• Identity: 146/547 - (26%)
• Similarity: 269/547 - (49%)
• Gaps: 53/547 - (9%)

  Fly     9 LLLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKPVVNHKNITV 73
            :.|.|.:.....|.....:| ::|: ..||.|...:..:.|.:.||.|||:|.....:
Human     8 VFLLIQLSCYFSSGSCGKVL-VWPT-EYSHWINMKTILEELVQRGHEVTVLTSSASTL------- 63

  Fly    74 IQVPLSKEEAQQMSDTIGAMSKNDNSNMALSLLRMSDQMDFMIRKNAETLMNDRVRDL---YLNR 135
              |..||..|.::.....:::||   .:..|||::.|:..:.:.||.......::::|   |.:.
Human    64 --VNASKSSAIKLEVYPTSLTKN---YLEDSLLKILDRWIYGVSKNTFWSYFSQLQELCWEYYDY 123

  Fly   136 GNKF--DLVISGYFM-----NDFQLGFARKVNAPVIVLA---TMPPNHLLNPLIGNPLEVSYAGI 190
            .||.  |.|::...|     :.|.:..|..:|....:||   .:|..:.|...:|...|.:..|.
Human   124 SNKLCKDAVLNKKLMMKLQESKFDVILADALNPCGELLAELFNIPFLYSLRFSVGYTFEKNGGGF 188

  Fly   191 SNP--------AEGSKAVTFQRRLSSYMQSLGFGVFSHLSERRNRNW---YKEVYGNDPKMPEYS 244
            ..|        :|.|..:.|..|:.:.:..|.|..:..:.:.  :.|   |.||.|....:   .
Human   189 LFPPSYVPVVMSELSDQMIFMERIKNMIHMLYFDFWFQIYDL--KKWDQFYSEVLGRPTTL---F 248

  Fly   245 EMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFL-GNATDGAILLSLG 308
            |.:....:....::...|.| ||.:|:...:||:..| ...|||:.:.||: .:..:|.::.|||
Human   249 ETMGKAEMWLIRTYWDFEFP-RPFLPNVDFVGGLHCK-PAKPLPKEMEEFVQSSGENGIVVFSLG 311

  Fly   309 SNVQGKHLNPDTVAKMFNVLSKLKERVIWKWEDQE-NTPGKSANILYSKWLPQDDILAHPNIKLF 372
            |.:  .:::.::...:.:.|:::.::|:|:::.:: ||.|.:.. || |||||:|:|.||..|.|
Human   312 SMI--SNMSEESANMIASALAQIPQKVLWRFDGKKPNTLGSNTR-LY-KWLPQNDLLGHPKTKAF 372

  Fly   373 INHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILEILSNP 437
            |.|.|..||.|:.|||.||:.:|:||||..|...|...|..|::.:.|:..:....|:..::::|
Human   373 ITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRTMSSRDLLNALKSVINDP 437

  Fly   438 QYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMSFIAANNID-ICFLIFVI 501
            .|.|.|...|.::.|:||...:..::|.|:|:||.||.||:....::::|..:::| |.||:..:
Human   438 VYKENVMKLSRIHHDQPMKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWIQYHSLDVIAFLLACV 502

  Fly   502 LVSVLVLIKFLVQFIYRRFISKPKKEK 528
            ...:.::.||.: |.:|:...|.||:|
Human   503 ATVIFIITKFCL-FCFRKLAKKGKKKK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	egt	1..490	CDD:223071	134/506 (26%)
		UDPGT	37..526	CDD:278624	138/515 (27%)
UGT2B15	NP_001067.2	egt	8..508	CDD:223071	138/524 (26%)
		UDPGT	24..518	CDD:278624	138/519 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150295
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840