Protein Alignment Ugt37A3 and UGT2B7

DIOPT Version :9

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001065.2
• Gene: UGT2B7 / 7364
• HGNCID: 12554
• Length: 529
• Species: Homo sapiens
• Alignment Length: 536
• Identity: 136/536 - (25%)
• Similarity: 253/536 - (47%)
• Gaps: 64/536 - (11%)

  Fly    39 LIIQMS-------AAKVL---AENGHNVTVVTVLKPVVNH-KNITVIQVPLS------KEEAQQM 86
            |:||:|       ..|||   ||..|.:.:.|:|..::.. ..:||:....|      ...|.::
Human    10 LLIQLSFCFSSGNCGKVLVWAAEYSHWMNIKTILDELIQRGHEVTVLASSASILFDPNNSSALKI 74

  Fly    87 SDTIGAMSKNDNSNMAL-SLLRMSDQMDFMIRKNAETLMNDRVRDLYLNRGN---KF--DLVISG 145
            .....:::|.:..|..: .:.|.||     :.|:...|...:|:::....|:   ||  |:|.:.
Human    75 EIYPTSLTKTELENFIMQQIKRWSD-----LPKDTFWLYFSQVQEIMSIFGDITRKFCKDVVSNK 134

  Fly   146 YFM-----NDFQLGFARKV-----------NAPVIVLATMPPNHLLNPLIGNPL-EVSYAGISNP 193
            .||     :.|.:.||..:           |.|.:...:..|.:......|..: ..||..:. .
Human   135 KFMKKVQESRFDVIFADAIFPCSELLAELFNIPFVYSLSFSPGYTFEKHSGGFIFPPSYVPVV-M 198

  Fly   194 AEGSKAVTFQRRLSSYMQSLGFGVFSHLSERRNRNW---YKEVYGNDPKMPEYSEMLK-NTSLVF 254
            :|.:..:||..|:.:.:..|.|..:..:.:.  :.|   |.||.|....:.|  .|.| :..|:.
Human   199 SELTDQMTFMERVKNMIYVLYFDFWFEIFDM--KKWDQFYSEVLGRPTTLSE--TMGKADVWLIR 259

  Fly   255 FSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFL-GNATDGAILLSLGSNVQGKHLNP 318
            .|.:.....|:.|||..   :||:..| ...|||:.:.:|: .:..:|.::.||||.|  .::..
Human   260 NSWNFQFPYPLLPNVDF---VGGLHCK-PAKPLPKEMEDFVQSSGENGVVVFSLGSMV--SNMTE 318

  Fly   319 DTVAKMFNVLSKLKERVIWKWE-DQENTPGKSANILYSKWLPQDDILAHPNIKLFINHAGKGGIT 382
            :....:.:.|:::.::|:|::: ::.:|.|.:.. || ||:||:|:|.||..:.||.|.|..||.
Human   319 ERANVIASALAQIPQKVLWRFDGNKPDTLGLNTR-LY-KWIPQNDLLGHPKTRAFITHGGANGIY 381

  Fly   383 ESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILEILSNPQYAERVKSFS 447
            |:.|||.||:.:|:|||||.|...|...|..:.:...|:.......|:..::::|.|.|.|...|
Human   382 EAIYHGIPMVGIPLFADQPDNIAHMKARGAAVRVDFNTMSSTDLLNALKRVINDPSYKENVMKLS 446

  Fly   448 TLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDICFLIFVILVSVLVLIKFL 512
            .:..|:|:...:..::|.|:|:||.||.||:.....:::...:::|:...:.|.:.:|:.::...
Human   447 RIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVIGFLLVCVATVIFIVTKC 511

  Fly   513 VQFIYRRFISKPKKEK 528
            ..|.:.:|..|.||.|
Human   512 CLFCFWKFARKAKKGK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	egt	1..490	CDD:223071	127/496 (26%)
		UDPGT	37..526	CDD:278624	133/532 (25%)
UGT2B7	NP_001065.2	UDPGT	24..525	CDD:278624	129/518 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150463
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840