Protein Alignment Ugt37A3 and Ugt1a5

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001034638.1
• Gene: Ugt1a5 / 574523
• RGDID: 1583689
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 554
• Identity: 144/554 - (25%)
• Similarity: 243/554 - (43%)
• Gaps: 90/554 - (16%)

  Fly    22 SQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTV----VTVLKPVVNHKNITVIQVPLSKEE 82
            ::|..:| :|| :..||.:......:.|...||...|    |||.....:...:....||.:::.
  Rat    23 AEGGKVL-VFP-MEGSHWLSMRDVVRELHARGHQAVVLAPEVTVHIKEEDFFTLQTYPVPYTRQG 85

  Fly    83 AQQMSDTIGAMSKN-----DNSNMALSLLRMSDQMDFMIRKNAETLMNDRVRDLYLN-------R 135
            .:|.      |.:|     :..|...:.|..|:     |.||..|::.....:|..|       .
  Rat    86 FRQQ------MMRNIKVVFETGNYVKTFLETSE-----ILKNISTVLLRSCMNLLHNGSLLQHLN 139

  Fly   136 GNKFDLVISGYFMNDFQLGFARKVNAPVIVLATMPPNHLLNPLIGNP----LEVSYAGISNPAEG 196
            .:.||:|::.                |||     |...:|...:|.|    |.....||.:.|..
  Rat   140 SSSFDMVLTD----------------PVI-----PCGAVLAKYLGIPTVFFLRYIPCGIDSEATQ 183

  Fly   197 ---------------SKAVTFQRRLSSYMQSLGFGVFSHLSERRNRNWYKEVYGNDPKMPEYSEM 246
                           |..:||.:|:.:.:..|......|.|..|..:...|:...:..:   .|:
  Rat   184 CPKPSSYIPNLLTMLSDHMTFLQRVKNMLYPLALKYICHFSFTRYESLASELLQREVSL---VEV 245

  Fly   247 LKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFLGNAT--DGAILLSLGS 309
            |.:.|:..|......:.| ||.:|:.:.||||....| .||.|....:: ||:  .|.::.||||
  Rat   246 LSHASVWLFRGDFVFDYP-RPVMPNMVFIGGINCVIK-KPLSQEFEAYV-NASGEHGIVVFSLGS 307

  Fly   310 NVQGKHLNPDTVAKMFNVLSKLKERVIWKWEDQENTPGKSA-NILYSKWLPQDDILAHPNIKLFI 373
            .|  ..:......::...|.::.:.|:|::..  ..|...| |.:..|||||:|:|.||..:.||
  Rat   308 MV--SEIPEKKAMEIAEALGRIPQTVLWRYTG--TRPSNLAKNTILVKWLPQNDLLGHPKARAFI 368

  Fly   374 NHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILEILSNPQ 438
            .|:|..||.|...:|.||:.:|:|.||..||..|...|.|:||::|.:.....:.|:..:::|..
  Rat   369 THSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKS 433

  Fly   439 YAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVH-MSFIAANNIDIC-FLIFVI 501
            |.|.:...|:|::|||:...:..::|.|||:||.||.||: |..| :::...:::|:. ||:.::
  Rat   434 YKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAIV 497

  Fly   502 LVSVLVLIKFLVQFIYRRF-----ISKPKKEKTH 530
            |..|.::.|.......:.|     :.|..|.|||
  Rat   498 LTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	119/476 (25%)
Ugt1a5	NP_001034638.1	UDPGT	26..522	CDD:278624	138/540 (26%)