Protein Alignment Ugt37A3 and ugt1b1

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001170917.1
• Gene: ugt1b1 / 558508
• ZFINID: ZDB-GENE-080227-10
• Length: 528
• Species: Danio rerio
• Alignment Length: 564
• Identity: 143/564 - (25%)
• Similarity: 258/564 - (45%)
• Gaps: 96/564 - (17%)

  Fly    10 LLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKPVVNHKNITV- 73
            ||.:.:.|.:...||..:| :.| :..||.:.....|..||..||:|.|      :|..|||.:
Zfish    14 LLLLWLSAGLRPVQGGRVL-VMP-VEGSHWLSMKVLATELARRGHDVLV------LVPEKNILIQ 70

  Fly    74 ---------IQVPLSKEEAQQMSDTI-----GAMSKNDNSNMALSLLRMSDQMDFMIR------K 118
                     ..|.:|||   |:|.::     |..:::.      :|:.:..|::.::.      :
Zfish    71 SSELFRTETFPVKISKE---QLSKSLKGFQQGVFTRSP------ALMDVFVQLERLLNFTGSQVE 126

  Fly   119 NAETLMNDR--VRDLYLNRGNKFDLVISGYFMNDFQLGFARKVNAPVIVLAT-MPPNHLLNPLIG 180
            ..|:|:.:.  :|.|   :...|:|:::..|:          ...|:|..|. :|..:.|.   |
Zfish   127 GCESLLYNEPLMRKL---KEQNFELMLTDPFL----------PCGPIIATALGVPAVYFLR---G 175

  Fly   181 NPLEVSYAGISNPAE----------GSKAVTFQRRLSSYMQSLGFG------VFSHLSERRNRNW 229
            .|..:.......|:.          .|..:.|..|:.::..| ||.      :::...|...|..
Zfish   176 MPCGIDLLASQCPSPPSYVPRFHSGTSDKMNFVERIRNFFMS-GFELVLCKVMYASFDELAARYL 239

  Fly   230 YKEVYGNDPKMPEYSEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEF 294
            .|:|        .|.|::...:|.........|.| ||.:|:.:.||||..: |...:...:.||
Zfish   240 KKDV--------TYKEIIGRGALWLHRYDFTFEYP-RPIMPNMVFIGGINCQ-KSAEISAEVEEF 294

  Fly   295 L-GNATDGAILLSLGSNVQGKHLNPDTVAKM-FNVLSKLKERVIWKW--EDQENTPGKSANILYS 355
            : |:...|.::.||||.|...   |...|.: |...|.:.:||:|::  |..:|.|   .|:...
Zfish   295 VNGSGEHGIVVFSLGSLVSSM---PKEKADIFFKAFSMIPQRVLWRYTGEIPDNVP---ENVKLM 353

  Fly   356 KWLPQDDILAHPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLT 420
            |||||:|:|.||..:.||.|.|..||.|....|.||:.||:|.||..|.:.:...|.|:.||:..
Zfish   354 KWLPQNDLLGHPKARAFITHGGTHGIYEGICRGVPMVMLPLFGDQADNVHRVATRGVGVILSIHD 418

  Fly   421 LEEKPFQEAILEILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMS 485
            :..:...:|:..:::|..|.::::..|.::.|||:...:..::|||:|:||.||.||:.....::
Zfish   419 ITVETLLDALNSVINNSSYKQKMQKLSAIHNDRPIQPLDLAVFWTEFVMRHKGADHLRPAAHELN 483

  Fly   486 FIAANNIDIC-FLIFVILVSVLVLIKFLVQFIYRRFISKPKKEK 528
            ::..:::|:. |::.::|:..|.::| .....:||...|.:|.|
Zfish   484 WLQYHSLDVIGFMLLIVLIVTLAMLK-CCSLCWRRCCRKTQKRK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	118/482 (24%)
ugt1b1	NP_001170917.1	UDPGT	29..524	CDD:278624	136/545 (25%)