Protein Alignment Ugt37A3 and Ugt2a2

DIOPT Version :9

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001019319.1
• Gene: Ugt2a2 / 552899
• MGIID: 3576095
• Length: 528
• Species: Mus musculus
• Alignment Length: 554
• Identity: 132/554 - (23%)
• Similarity: 264/554 - (47%)
• Gaps: 54/554 - (9%)

  Fly     1 MVLRVEKFLLLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKPV 65
            |:.:|.:.|:..:.:..::.|   .|:: ::|: ..||.:......:.|.:..|:|||:...:.:
Mouse     1 MIKKVLQLLIFHLTLAEIVLS---GNVV-VWPT-DGSHWLNIKILLEELVQRNHSVTVLAPSETL 60

  Fly    66 -VNHK-----NITVIQVPLSKEEAQQMSDTIGAM-------------SKNDNSNMALSLLRMSDQ 111
             :|.:     |...|.|..:|.:..::.:.:.|:             ...:..|:..:....:.|
Mouse    61 FINSRLDAFINFEEIPVSYTKSKIDEIIEHMIALWLDHRPTPLTMWTFYKELGNLLATFYTTNKQ 125

  Fly   112 M-DFMIRKNAETLMNDRVRDLYLNRGNKFDLVISGYFMNDFQLGFARKVNAPVIVLATMPPNHLL 175
            | |.::  |..|:|.      .|.:|. ||::::.......:| .|.|:..|.:......|...:
Mouse   126 MCDGVL--NNPTVME------RLQKGG-FDVLLADPVTMCGEL-VALKLGIPFVYTLRFSPAFTV 180

  Fly   176 NPLIGN-PLEVSY--AGISNPAEGSKAVTFQRRLSSYMQ-SLGFGVFSHLSERRNRNWYKEVYGN 236
            ....|. |..:||  |.:|   |.:..::|..|:.:.:. ||...:|.......| ::|.:|.|.
Mouse   181 ERHCGKIPAPISYVPAALS---ELTDQMSFGERVKNIISYSLQDYIFKTYWGEWN-SYYSKVLGR 241

  Fly   237 DPKMPEYSEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFLGNATD- 300
            ...:   .|.:....:....::...|.| ||.:|:...:||:..| ...|||:.:.||:..:.:
Mouse   242 PTTL---CETMGKAEIWLMRTYWDFEFP-RPYLPNFEFVGGLHCK-PAKPLPKEMEEFVQTSGEH 301

  Fly   301 GAILLSLGSNVQGKHLNPDTVAKMFNVLSKLKERVIWKWEDQ-ENTPGKSANILYSKWLPQDDIL 364
            |.::.||||.|  |:|..:....:.:.|:::.::|:|:::.: .:|.|.:..:.  .|:||:|:|
Mouse   302 GIVVFSLGSMV--KNLTDEKANLIASALAQIPQKVLWRYKGKIPDTLGSNTRLF--DWIPQNDLL 362

  Fly   365 AHPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEA 429
            .||..:.||.|.|..||.|:.|||.||:.:|:|||||.|...|...|..:.:::.|:.......|
Mouse   363 GHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNA 427

  Fly   430 ILEILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDI 494
            :..:::.|.|.|.....|.::.|:|:...:..::|.|:|:||.||.||:.....:|:...:::|:
Mouse   428 LRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDV 492

  Fly   495 CFLIFVILVSVLVLIKFLVQFIYRRFISKPKKEK 528
            ...:...:.|.::|:.....||:::.....||:|
Mouse   493 IGFLLACVASAILLVAKCCLFIFQKVGKTGKKKK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	egt	1..490	CDD:223071	124/514 (24%)
		UDPGT	37..526	CDD:278624	123/514 (24%)
Ugt2a2	NP_001019319.1	UDPGT	22..516	CDD:278624	125/518 (24%)
		egt	<267..487	CDD:223071	70/224 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840214
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840