Protein Alignment Ugt37A3 and UGT1A10

DIOPT Version :9

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_061948.1
• Gene: UGT1A10 / 54575
• HGNCID: 12531
• Length: 530
• Species: Homo sapiens
• Alignment Length: 553
• Identity: 151/553 - (27%)
• Similarity: 257/553 - (46%)
• Gaps: 67/553 - (12%)

  Fly    11 LAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKPVVNHK-----N 70
            |.:.:....|.::...:| :.| :..||.....|..:.|...||.|.||   .|.|:.:     |
Human    12 LCVCLLLTCGFAEAGKLL-VVP-MDGSHWFTMQSVVEKLILRGHEVVVV---MPEVSWQLERSLN 71

  Fly    71 ITVIQVPLSKE-EAQQMSDTIGAMSKNDNSNMALSLLRMSDQMDF--MIRKNAETLMNDRVRDLY 132
            .||.....|.. |.|.....:.|.::......::..|.||....|  :...:..:|.|||....|
Human    72 CTVKTYSTSYTLEDQNREFMVFAHAQWKAQAQSIFSLLMSSSSGFLDLFFSHCRSLFNDRKLVEY 136

  Fly   133 LNRGNKFDLVISGYFMNDFQ---LGFARKVNAPVIVLATMPPNHLLNPLIGNPLEVSYAGISNPA 194
            | :.:.||.|    |::.|.   |..|:..:.|.:|.......|.|......|..:||  :.|..
Human   137 L-KESSFDAV----FLDPFDTCGLIVAKYFSLPSVVFTRGIFCHHLEEGAQCPAPLSY--VPNDL 194

  Fly   195 EG-SKAVTFQRRLSSYMQSLGFGVFSHLSERRNRNWYKEVYGNDPKMPEYSEMLK---------- 248
            .| |.|:||:.|           |::|:....:..:.:.::.|..::.  ||:|:
Human   195 LGFSDAMTFKER-----------VWNHIVHLEDHLFCQYLFRNALEIA--SEILQTPVTAYDLYS 246

  Fly   249 NTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFLGNAT--DGAILLSLGSNV 311
            :||:....:....:.| :|.:|:.|.||||.. .:..|||.....:: ||:  .|.::.||||.|
Human   247 HTSIWLLRTDFVLDYP-KPVMPNMIFIGGINC-HQGKPLPMEFEAYI-NASGEHGIVVFSLGSMV 308

  Fly   312 QGKHLNPDTVAKMFNVLSKLKERVIWKWEDQENTPGKSA-NILYSKWLPQDDILAHPNIKLFINH 375
              ..:.......:.:.|.|:.:.|:|::..  ..|...| |.:..|||||:|:|.||..:.||.|
Human   309 --SEIPEKKAMAIADALGKIPQTVLWRYTG--TRPSNLANNTILVKWLPQNDLLGHPMTRAFITH 369

  Fly   376 AGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILEILSNPQYA 440
            ||..|:.||..:|.||:.:|:|.||..||..|...|.|:||::|.:..:..:.|:..::::..|.
Human   370 AGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYK 434

  Fly   441 ERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVH-MSFIAANNIDIC-FLIFVILV 503
            |.:...|:|::|||:...:..::|.|:|:||.||.||: |..| :::...:::|:. ||:.|:|.
Human   435 ENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAVVLT 498

  Fly   504 SVLVLIKFLVQFIYRRF------ISKPKKEKTH 530
            ...:..| ...:.||:.      :.|..|.|||
Human   499 VAFITFK-CCAYGYRKCLGKKGRVKKAHKSKTH 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	egt	1..490	CDD:223071	138/504 (27%)
		UDPGT	37..526	CDD:278624	143/521 (27%)
UGT1A10	NP_061948.1	UDPGT	26..521	CDD:278624	144/528 (27%)
		egt	<258..504	CDD:223071	82/253 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150404
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840