Protein Alignment Ugt37A3 and Ugt35E2

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_652623.2
• Gene: Ugt35E2 / 53506
• FlyBaseID: FBgn0040255
• Length: 527
• Species: Drosophila melanogaster
• Alignment Length: 545
• Identity: 169/545 - (31%)
• Similarity: 288/545 - (52%)
• Gaps: 49/545 - (8%)

  Fly     1 MVLRVEKFLLLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVT---VL 62
            |.:.|.:.::|.:|:..|:  .:||.|||:||..|.||....:...|.||..||.:|.|:   :.
  Fly     3 MSMLVLRLIVLVVALLPVL--LEGARILGVFPIPSHSHYYHALPYLKKLASLGHEITSVSPFPLK 65

  Fly    63 KPVVNHKNITVIQVPLSKEE-AQQMSDTIGAMSKNDNSNM-ALSLLRMSDQMDFMIRKNAETLMN 125
            :||.|..:|.|.::..:.|| ...:::..|..::.:..|. .|.|:.             :.|.|
  Fly    66 EPVANIHDIPVPELFDNIEEIVGNLTNRKGTWNEFEYINQYTLGLVE-------------KVLEN 117

  Fly   126 DRV-RDLYLNRGNKFDLVISGYFMNDFQLGFARKVNAPVIVLATMPPNHLLNPLIGNPLEVSYAG 189
            |.| |::......:|||:|...:..|...|.|...:||:|.:|:...:..::.|:||...::|
  Fly   118 DGVRREILQPESLQFDLIIVDLWRLDALYGLAAYFDAPIIGIASYGTDWKIDELVGNVSPLAY-- 180

  Fly   190 ISNPA-EGSKAVTFQRRLSSYM-QSLGFGVFSHLSERRNRNWYKEVYGNDPKMPE---YSEMLKN 249
            :.:|: ......|:..||..:: ||:.:..:....|.|:...|::.:   ||:.:   .||:.:|
  Fly   181 LQSPSFNWFDLDTYGGRLGHFVDQSMAWINWHWRHEERHEAVYRKYF---PKIADKRSLSEITRN 242

  Fly   250 TSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFL-GNATDGAILLSLGSNVQG 313
            .:|:..:.| .:..|.||.||:.||:||:.:..:|..|||::.:|: |....|.|..|||:||:.
  Fly   243 FALILVNQH-FTMAPPRPYVPNIIEVGGMHVDQQPKALPQDLEDFIQGAGEHGVIYFSLGTNVRS 306

  Fly   314 KHLNPDTVAKMFNVLSKLKERVIWKWEDQE--NTPGKSANILYSKWLPQDDILAHPNIKLFINHA 376
            ::|:.|....:.:..:.|.:|::||::..|  :.|   :|:|.|.|.||.|||||||:||||.|.
  Fly   307 RNLSKDRRKILIDTFASLPQRILWKFDADELSDVP---SNVLISPWFPQQDILAHPNVKLFITHG 368

  Fly   377 GKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILEILSNPQYAE 441
            |.....|..:.|.|||.||.|.||.||...:...|.||.|:...:....|::.|.::|:...:..
  Fly   369 GLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFKDTIHQLLTEKSFGV 433

  Fly   442 RVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDI--CFLIFV-ILV 503
            :.|..:..|||:||...::.::||.||:||.||.|::....::.||..:::|:  .||:.| .::
  Fly   434 KAKRTADRYRDQPMNPLDTAIWWTHYVLRHKGAPHMRVAGRNLDFITYHSLDVLGTFLLAVWAIL 498

  Fly   504 SVLVL--IKFLVQFIYRRFISKPKK 526
            |::||  ||.|      |.|.|.||
  Fly   499 SIVVLCAIKLL------RAILKSKK 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	137/452 (30%)
Ugt35E2	NP_652623.2	MGT	31..443	CDD:273616	128/433 (30%)
		Glycosyltransferase_GTB-type	<247..517	CDD:471961	99/279 (35%)