Protein Alignment Ugt37A3 and Ugt8

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_062149.1
• Gene: Ugt8 / 50555
• RGDID: 3938
• Length: 541
• Species: Rattus norvegicus
• Alignment Length: 543
• Identity: 146/543 - (26%)
• Similarity: 262/543 - (48%)
• Gaps: 79/543 - (14%)

  Fly     8 FLLLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTV-----LKPVVN 67
            |:||..|:|.    ::.|.|:.:.|.:..|||.|..:.|..|.|.||: ||..:     :.| .|
  Rat     8 FMLLWSAVGI----ARAAKIIIVPPIMFESHLYIFKTLASALHERGHH-TVFLLSEGRDIDP-SN 66

  Fly    68 HKNITVIQVPLSKEEAQQMSDTIGAMSKNDNSNM---ALSLLRMSDQMDFMIRKNAETLMNDRVR 129
            |.:       |.:......|.|..|..::...|:   .|:.:.:.|.:|. ..||.:.::.::..
  Rat    67 HYS-------LQRYPGIFNSTTSDAFLQSKMRNIFSGRLTAVELVDILDH-YTKNCDMMVGNQAL 123

  Fly   130 DLYLNRGNKFDLVISGYFMNDFQLGFARKVNAPVIVLATMPPNHLLNPLIGNPLEVSYA----GI 190
            ...|.: .||||::                         :.||.:...:|.:.|.|.||    |:
  Rat   124 IQGLKK-EKFDLLL-------------------------VDPNDMCGFVIAHLLGVKYAVFSTGL 162

  Fly   191 SNPAE-GSKA-----VTFQRRLSSYMQSL----GFGVFSHLSERRNRNW-----YKEVYGNDPKM 240
            ..||| |:.|     ..|...|:..|..|    ..||:  |..|...::     |:.:......:
  Rat   163 WYPAEVGAPAPLAYVPEFNSLLTDRMNFLERMKNTGVY--LISRMGVSFLVLPKYERIMQKYNLL 225

  Fly   241 PEYS--EMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFLGNATD-GA 302
            |..|  :::..:||....:..|.|.| ||.:|:.:.:|||..| ...|||:::..::..|.: |.
  Rat   226 PAKSMYDLVHGSSLWMLCTDVALEFP-RPTLPNVVYVGGILTK-PASPLPEDLQRWVDGAQEHGF 288

  Fly   303 ILLSLGSNVQGKHLNPDTVAKMFNVLSKLKERVIWKWE-DQENTPGKSANILYSKWLPQDDILAH 366
            :|:|.|:.|  |:|:.|...|:...|.:|.::|||::. .:....|.:..::  :||||:|:|.|
  Rat   289 VLVSFGAGV--KYLSEDIANKLAGALGRLPQKVIWRFSGTKPKNLGNNTKLI--EWLPQNDLLGH 349

  Fly   367 PNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAIL 431
            .||:.|::|.|...|.|:.|||.|::.:|:|.|.......:...|.|:.|...|:.|....:|::
  Rat   350 SNIRAFLSHGGLNSIFETMYHGVPVVGIPLFGDHYDTMTRVQAKGMGILLEWNTVTEGELYDALV 414

  Fly   432 EILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDICF 496
            ::::||.|.:|.:..|.:::|:|........||.:|::||.||.||:|.:..:||.....:||.|
  Rat   415 KVINNPSYRQRAQKLSEIHKDQPGHPVNRTTYWIDYILRHDGAHHLRSAVHQISFCQYFLLDIAF 479

  Fly   497 LIFVILVSVLVLIKFLVQFIYRR 519
            ::.:..|::..::.::.:||||:
  Rat   480 VLLLGAVALYFIVSYVTKFIYRK 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	121/469 (26%)
Ugt8	NP_062149.1	Glycosyltransferase_GTB-type	21..502	CDD:471961	140/524 (27%)