Protein Alignment Ugt37A3 and Ugt1a6b

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_958812.3
• Gene: Ugt1a6b / 394435
• MGIID: 3580629
• Length: 531
• Species: Mus musculus
• Alignment Length: 560
• Identity: 154/560 - (27%)
• Similarity: 251/560 - (44%)
• Gaps: 104/560 - (18%)

  Fly    25 ANILG---LFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKPVVN-------HKNITVIQVPLS 79
            |::||   |......||.:......:.|:|.||:   :.||.|.||       :....:..||.|
Mouse    22 ASVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHD---IVVLVPEVNLLLGESKYYRRKIFSVPYS 83

  Fly    80 KEEAQQMSDT------------IGAMSKNDNSNMALSLLRMSDQMDFMIRKNAETLMNDRVRDLY 132
            .||.|....|            :|.:.:..||.:.|.          |...|.::|:.|.....:
Mouse    84 LEELQTRFRTFGRNQFVPGAPLMGPLREYRNSMLTLE----------MFFSNCQSLLKDSATLSF 138

  Fly   133 LNRGNKFDLVIS------GYFMNDFQLGFARKVNAPVIVLATMPPNHLLNPLIGNPLEVSYAGIS 191
            | |.||||.:.:      |..:.::       :|.|.:.|....|..|.:.|..:|..|||.
Mouse   139 L-RENKFDALFTDPAMPCGVILAEY-------LNLPSVYLFRGFPCSLEHMLGQSPSPVSYV--- 192

  Fly   192 NP---AEGSKAVTFQRRLSSYMQSLGFGVFSHLSERRNRNWY-----KEVYGND--------PKM 240
             |   .:.|..:||.:||::::.::          ..|..:|     .|:...|        |.:
Mouse   193 -PRFYTKFSDHMTFPQRLANFIVNI----------LENYLYYCLYSKYEIIVTDLLKRDVSLPSL 246

  Fly   241 PEYSEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFLGNAT--DGAI 303
            .:.|..|.....||       |.| ||.:|:.|.||||..| |...|.|....:: ||:  .|.:
Mouse   247 HQNSLWLLRYDFVF-------EYP-RPIMPNMIFIGGINCK-KKGKLTQEFEAYV-NASGEHGIV 301

  Fly   304 LLSLGSNVQGKHLNPDTVAKMFNVLSKLKERVIWKWEDQENTPGKSA-NILYSKWLPQDDILAHP 367
            :.||||.|  ..:......::...|.::.:.|:|::..  ..|...| |.:..|||||:|:|.||
Mouse   302 VFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTG--TRPSNLAKNTILVKWLPQNDLLGHP 362

  Fly   368 NIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILE 432
            ..:.||.|:|..||.|...:|.||:.:|:|.||..||..|...|.|:||::|.:.....:.|:..
Mouse   363 KTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKT 427

  Fly   433 ILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVH-MSFIAANNIDIC- 495
            :::|..|.|.:...|:|::|||:...:..::|.|||:||.||.||: |..| :::...:::|:.
Mouse   428 VINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIG 491

  Fly   496 FLIFVILVSVLVLIKFLVQFIYRRF-----ISKPKKEKTH 530
            ||:.::|..|.::.|.......:.|     :.|..|.|||
Mouse   492 FLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	130/485 (27%)
Ugt1a6b	NP_958812.3	UDPGT	27..522	CDD:278624	146/544 (27%)