Protein Alignment Ugt37A3 and Ugt1a5

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_964005.2
• Gene: Ugt1a5 / 394433
• MGIID: 3032634
• Length: 529
• Species: Mus musculus
• Alignment Length: 564
• Identity: 142/564 - (25%)
• Similarity: 247/564 - (43%)
• Gaps: 69/564 - (12%)

  Fly     1 MVLRVEKFLLLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKPV 65
            |.||:....|:.:.:...:..::|..:| :|| :..||.:......:.|...||.   ..||.|.
Mouse     1 MGLRMPLQGLVGLLLLCALPWTEGEKVL-VFP-VGGSHWLSMRDVVRELHAQGHQ---TVVLAPE 60

  Fly    66 VNHK-------NITVIQVPLSKEEAQQMSDTIGAMSKNDNSNMALSLLRMSD---QMDFMIRKNA 120
            ||.:       ...|..||.:::|.::|.:.:....  |..|....:.:.|:   .|..::.|..
Mouse    61 VNMRIKEEDFFTFKVYAVPYTRQELEEMMENLKVFF--DTGNYMKKIFKTSEALRNMSTVLLKTC 123

  Fly   121 ETLMNDRVRDLYLNRGNKFDLVISGYFMNDFQLGFARKVNAPVIVLATMPPNHLLNPLI----GN 181
            ..::::.....:|| .:.||:|.:.                ||.....:...:|..|.:    ..
Mouse   124 TNILHNESLLHHLN-SSSFDVVFTD----------------PVFPCGALLAKYLGIPAVFFLRYI 171

  Fly   182 PLEVSYAGISNPAEGSKAVTFQRRLSSYMQ----------SLGFGVFSHLSERRNRNWYKEVYGN 236
            |..:.|.....|:..|.......|||.:|.          .|......||......:...|::..
Mouse   172 PCGIEYEATQCPSPSSYIPNLFTRLSDHMDFLQRVQNMLYHLVLKYICHLLITPYESLASELFQR 236

  Fly   237 DPKMPEYSEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFLGNAT-- 299
            :...   .|:....|:..|......:.| ||.:|:.:.||||....| .||.|....:: ||:
Mouse   237 EVSS---VELFSYASVWLFRGDFVLDYP-RPIMPNMVFIGGINCVTK-KPLSQEFEAYV-NASGE 295

  Fly   300 DGAILLSLGSNVQGKHLNPDTVAKMFNVLSKLKERVIWKWEDQENTPGKSA-NILYSKWLPQDDI 363
            .|.::.||||.|  ..:......::...|.::.:.|:|::..  ..|...| |.:..|||||:|:
Mouse   296 HGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTG--TRPSNLAKNTILVKWLPQNDL 356

  Fly   364 LAHPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQE 428
            |.||..:.||.|:|..||.|...:|.||:.:|:|.||..||..|...|.|:||::|.:.....:.
Mouse   357 LGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLEN 421

  Fly   429 AILEILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVH-MSFIAANNI 492
            |:..:::|..|.|.:...|:|::|||:...:..::|.|||:||.||.||: |..| :::...:::
Mouse   422 ALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSL 485

  Fly   493 DIC-FLIFVILVSVLVLIKFLVQFIYRRF-----ISKPKKEKTH 530
            |:. ||:.::|..|.::.|.......:.|     :.|..|.|||
Mouse   486 DVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	113/465 (24%)
Ugt1a5	NP_964005.2	UDPGT	26..520	CDD:278624	132/528 (25%)