Protein Alignment Ugt37A3 and Ugt2b10

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001178605.1
• Gene: Ugt2b10 / 305264
• RGDID: 1309989
• Length: 532
• Species: Rattus norvegicus
• Alignment Length: 548
• Identity: 139/548 - (25%)
• Similarity: 248/548 - (45%)
• Gaps: 41/548 - (7%)

  Fly     2 VLRVEKFLLLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKP-- 64
            |.|....|||.:.:....||..|..:| ::| :..||.:........|.:.||.   ||||:|
  Rat     3 VKRTASLLLLLLQLSDFFGSGTGGKVL-VWP-MEFSHWLNLRVILDELLKKGHE---VTVLRPSA 62

  Fly    65 -----VVNHKNITVIQVPLSKEEA-------QQMSDTIGAMSKNDNSNMALSLLRM----SDQMD 113
                 |.|...|.....|.|....       :.:...|..:.|.......|....:    ||..:
  Rat    63 SLSYEVDNTSAIEFETYPTSYSLTEVDEFFWESLRKYIYELPKQSFWGYFLMFQELVWVDSDYFE 127

  Fly   114 FMIRKNAETLMNDRVRDLYLNRGNKFDLVISGYFMNDFQLGFARKVNAPVIVLATMPPNHLLNPL 178
            .:.:   :.:.|..:.....|.|  ||::::..|:....| .|..:..|::......|.......
  Rat   128 SLCK---DVVFNKELMTKLQNSG--FDVILADPFIPCGDL-LAEILKIPLVYSLRFFPGSTYEKY 186

  Fly   179 IGN-PLEVSYAGISNPAEGSKAVTFQRRLSSYMQSLGFGV-FSHLSERRNRNWYKEVYGNDPKMP 241
            .|. |:..||..|: .:|.|..:||..|:...:..|.|.. |...:|::....|.||.|....:
  Rat   187 SGGLPMPPSYVPIA-MSELSDRMTFVERMKHMIYVLCFDFWFQAFNEKKWNELYTEVLGRPTTL- 249

  Fly   242 EYSEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFLGNATD-GAILL 305
              ||.:....:....::...|.| .|.:|:...:||:..: ...|||:.|.:|:.::.: |.::.
  Rat   250 --SETMAKADIWLIRTYWDLEFP-HPVLPNFDFVGGLHCR-PAKPLPKEIEDFVQSSGEHGVVVF 310

  Fly   306 SLGSNVQGKHLNPDTVAKMFNVLSKLKERVIWKWEDQENTPGKSANILYSKWLPQDDILAHPNIK 370
            ||||.|  .:|..:....:...|:::.::|:|::|.::.....|...|| ||:||:|:|.||..:
  Rat   311 SLGSMV--GNLTEERANVIAAGLAQIPQKVLWRFEGKKPETLGSNTRLY-KWIPQNDLLGHPKTR 372

  Fly   371 LFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILEILS 435
            .||.|.|..||.|:.|||.|::.:|:|.||..|...:...|..:.|..||:.......|:..|.:
  Rat   373 AFITHGGTNGIYEAIYHGIPVVGIPLFGDQYDNIVHLKTKGAAVRLDFLTMSSTDLFTALKTITN 437

  Fly   436 NPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDICFLIFV 500
            :|.|.|.....|.::.|:|:...:..::|.|:|:||.||.||:.....:|::..:::|:...:..
  Rat   438 DPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWVQYHSLDVIGFLLA 502

  Fly   501 ILVSVLVLIKFLVQFIYRRFISKPKKEK 528
            .:|:|:.::|....|..::|....:|:|
  Rat   503 CVVTVMFILKKCCLFCCQKFTKAGRKKK 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	113/459 (25%)
Ugt2b10	NP_001178605.1	UDPGT	26..529	CDD:278624	129/522 (25%)