Protein Alignment Ugt37A3 and Ugt2b1

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_775417.1
• Gene: Ugt2b1 / 286954
• RGDID: 708541
• Length: 529
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 147/547 - (26%)
• Similarity: 269/547 - (49%)
• Gaps: 53/547 - (9%)

  Fly     8 FLLLAI-------AIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVT----- 60
            |||:.:       |.|.|:          ::|: ..||.|........||:.||.|||:.
  Rat     9 FLLIQLICYFRPGACGKVL----------VWPT-EYSHWINIKIILNELAQRGHEVTVLVSSASI 62

  Fly    61 VLKPVVNHK-NITVIQVPLSKEEAQ-QMSDTIGAMSKNDNSNMALSLLRMSDQMDFMIRKNAETL 123
            :::|..... |..:..|||||.:.: ..:..|...:::..:   ||:.....:|..:..:.::.:
  Rat    63 LIEPTKESSINFEIYSVPLSKSDLEYSFAKWIDEWTRDFET---LSIWTYYSKMQKVFNEYSDVV 124

  Fly   124 MNDRVRDLYLNR-------GNKFDLVISGYFMNDFQLGFARKVNAPVIVLATMPPNHLLNPLIGN 181
            .| ..:.|..|:       |::||::::.......:| .|..:..|::......|.:......|.
  Rat   125 EN-LCKALIWNKSLMKKLQGSQFDVILADAVGPCGEL-LAELLKTPLVYSLRFCPGYRCEKFSGG 187

  Fly   182 -PLEVSYAGISNPAEGSKAVTFQRRLSSYMQSLGFGV-FSHLSERRNRNWYKEVYGNDPKMPEYS 244
             ||..||..:. .:|.|..:||..|:.:.:|.|.|.. |....|:....:|.:|.|....:   :
  Rat   188 LPLPPSYVPVV-LSELSDRMTFVERVKNMLQMLYFDFWFQPFKEKSWSQFYSDVLGRPTTL---T 248

  Fly   245 EMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFLGNATD-GAILLSLG 308
            ||:....:....:....|.| .|.:|:...:||:..| ...|||:.:.||:.::.: |.::.|||
  Rat   249 EMMGKADIWLIRTFWDLEFP-HPFLPNFDFVGGLHCK-PAKPLPREMEEFVQSSGEHGVVVFSLG 311

  Fly   309 SNVQGKHLNPDTVAKMFNVLSKLKERVIWKWEDQE-NTPGKSANILYSKWLPQDDILAHPNIKLF 372
            |.|  |:|..:....:.:.|:::.::|:|:::.:: :|.|.:.. || ||:||:|:|.||..|.|
  Rat   312 SMV--KNLTEEKANVVASALAQIPQKVVWRFDGKKPDTLGSNTR-LY-KWIPQNDLLGHPKTKAF 372

  Fly   373 INHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILEILSNP 437
            :.|.|..||.|:.|||.|::.:|:|||||.|.|.||..|..:.:....|.......|:..::::|
  Rat   373 VAHGGTNGIYEAIYHGIPIVGIPLFADQPDNINHMVAKGAAVRVDFSILSTTGLLTALKIVMNDP 437

  Fly   438 QYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDIC-FLIFVI 501
            .|.|.....|.::.|:|:...:..::|.|||:||.||.||:|.|..:|:...:::|:. ||:..:
  Rat   438 SYKENAMRLSRIHHDQPVKPLDRAVFWIEYVMRHKGAKHLRSTLHDLSWFQYHSLDVIGFLLLCV 502

  Fly   502 LVSVLVLIKFLVQFIYRRFISKPKKEK 528
            :..|.::.||.: |..|:..:..||:|
  Rat   503 VGVVFIITKFCL-FCCRKTANMGKKKK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	117/456 (26%)
Ugt2b1	NP_775417.1	UDPGT	24..527	CDD:278624	141/529 (27%)