Protein Alignment Ugt37A3 and Ugt2b

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_113721.5
• Gene: Ugt2b / 24862
• RGDID: 3936
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 511
• Identity: 143/511 - (27%)
• Similarity: 241/511 - (47%)
• Gaps: 59/511 - (11%)

  Fly    49 LAENGHNVTVVTVLKPVV---------NHKNITVIQVPLSKEEAQQ-------------MSDTIG 91
            |.:.||.   ||||||..         :.....:....:||:|.|.             ..||..
  Rat    46 LVQRGHE---VTVLKPSAYFFLDPKKSSDLKFEIFSTSISKDELQNHFIKLLDVWTYELPRDTCL 107

  Fly    92 AMSK-NDNSNMALSLLRMSDQMDFMIRKNAETLMNDRVRDLYLNRGNKFDLVISGYFMNDFQLGF 155
            :.|. ..|.....|...:|...|.:..|...|.:.:          :|||::.:....:...| .
  Rat   108 SYSPILQNLVYEFSYFYLSICKDAVSNKQLMTKLQE----------SKFDVLFADPVASCGDL-I 161

  Fly   156 ARKVNAPVIVLATMPPNHLLNPLIGN-PLEVSYAGISNPAEGSKAVTFQRRLSSYMQSLGFGVFS 219
            |..::.|.:...:..|.|.|...||. .|..||..:.......| :||..|:.:.:..|.|..:.
  Rat   162 AELLHIPFLYSLSFSPGHKLEKSIGKFILPPSYVPVILSGLAGK-MTFIDRVKNMICMLYFDFWF 225

  Fly   220 HLSERRNRNW---YKEVYGNDPKMPEYSEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIK 281
            .:  .|::.|   |.|:.|....:   .|.:....:....|:...:.| .|.:|:...|||:..|
  Rat   226 EI--LRHKEWDTFYSEILGRPTTV---DETMSKVEIWLIRSYWDLKFP-HPTLPNVDYIGGLHCK 284

  Fly   282 DKPDPLPQNIAEFLGNATD-GAILLSLGSNVQGKHLNPDTVAKMFNVLSKLKERVIWKWEDQENT 345
             ...|||:::.||:.::.: |.::.||||.|  .::..:....:...|:::.::|:||::.:  |
  Rat   285 -PAKPLPKDMEEFVQSSGEHGVVVFSLGSMV--SNMTEEKANAIAWALAQIPQKVLWKFDGK--T 344

  Fly   346 PGK-SANILYSKWLPQDDILAHPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVK 409
            |.. ..|....|||||:|||.||..|.|:.|.|..|:.|:.|||.||:.:|:|.|||.|...||.
  Rat   345 PATLGPNTRVYKWLPQNDILGHPKTKAFVTHGGANGLYEAIYHGIPMIGIPLFGDQPDNIAHMVA 409

  Fly   410 SGFGLTLSLLTLEEKPFQEAILEILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGA 474
            .|..::|::.|:.:..|..|:.|::.||.|.:.|...||::.|:||...:..::|.|:::||.||
  Rat   410 KGAAVSLNIRTMSKLDFLSALEEVIDNPFYKKNVMLLSTIHHDQPMKPLDRAVFWIEFIMRHKGA 474

  Fly   475 AHLQSPLVH-MSFIAANNIDIC-FLIFVILVSVLVLIKFLVQFIYRRFISKPKKEK 528
            .||: ||.| :.:...:::|:. ||:....|...:.:|.|: |:||.|:.|.||.|
  Rat   475 KHLR-PLGHNLPWYQYHSLDVIGFLLTCFAVIAALTVKCLL-FMYRFFVKKEKKMK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	118/443 (27%)
Ugt2b	NP_113721.5	UDPGT	24..527	CDD:278624	141/508 (28%)