Protein Alignment Ugt37A3 and Ugt50B3

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_724417.3
• Gene: Ugt50B3 / 246614
• FlyBaseID: FBgn0050438
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 556
• Identity: 153/556 - (27%)
• Similarity: 263/556 - (47%)
• Gaps: 61/556 - (10%)

  Fly     1 MVLRVEKFLLL----AIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTV 61
            |:.::..||::    .:|...:|.:..|          :.||.|.....||.|...|||:|.::.
  Fly     1 MLKKIALFLIIWSCGTLAADILMATQGG----------TKSHKIPFWELAKGLISRGHNITFLSG 55

  Fly    62 LKPVVNHKNITVIQVPLSKEEAQQMS--DTIGAMSKNDNSNMALSLLRMS-DQMDFMIRKNAETL 123
            .....|.:.:..:......|.....:  |.:|:....:........||.: :..|.|:| ::||
  Fly    56 FPADFNIEGLLEVTPAGLVEYIHNYTNWDLLGSRMAGEMPIKPWDGLRYAFESCDAMLR-DSET- 118

  Fly   124 MNDRVRDLYLNRGNKFDL-VISGYFMNDFQLGFARKVNAPVIVLATMPPNHLLNPLIGNPLEVSY 187
                 ::|   ....||| ::.|.|...| ||.......|.:.:.|:..........|||  |||
  Fly   119 -----KEL---TKKSFDLAILDGAFPECF-LGLMYDFKIPFMYINTVGFYTGSISTAGNP--VSY 172

  Fly   188 AGISNPAEGSKAV----TFQRRLSSYMQSLGFGVFSHLSERRNRNWYKEVYGNDPKMPEYSEMLK 248
            |  ..|...|:..    .::|.:::.|| :|..:......||.....:|..|.  ::|...||.:
  Fly   173 A--ITPNFYSRFTDTMNLYERAINTAMQ-IGQTLMHMYVMRRTHLVMREHLGT--QIPHPYEMSR 232

  Fly   249 NTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFLG-NATDGAILLSLGSNVQ 312
            |.|.:..:.||....| |...|:..|:..|..: ....||:|:.||:| :...|.|.:|:||:|:
  Fly   233 NVSFILQNGHAVLSYP-RAFNPNVAEVACIHCR-PARKLPRNLEEFIGASGASGFIYVSMGSSVK 295

  Fly   313 GKHLNPDTVAKMF-NVLSKLKERVIWKWEDQENTPGK--SANILYSKWLPQDDILAHPNIKLFIN 374
            ..:: |:.:..|. ...::|...|:||:|. .:|..|  ::|:..|:||||.|||.||.::.|:.
  Fly   296 AANM-PEALRHMLVKTFARLPYHVLWKYEG-SSTDIKDITSNVKLSRWLPQQDILGHPKLRAFVT 358

  Fly   375 HAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILEILSNPQY 439
            |.|...:.|:.|||.|::::|||.|...|:......|:.:.|.|.||......:||::::.||:|
  Fly   359 HGGLLSMFETVYHGVPVVTMPVFCDHDVNSAKAEVDGYAIKLDLQTLSANQLYKAIMKVIHNPRY 423

  Fly   440 AERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDICFLIFVILVS 504
            ....:....|:.|:..||.::.:||||||:||:||.|||:|..:|::.....:|: ..:::||:.
  Fly   424 RNSARHRQKLFLDQRSTALDTAIYWTEYVLRHNGAYHLQTPSRNMTWWQYYLLDV-VAVYLILLY 487

  Fly   505 VLVLIKFLVQFIYRRF------------ISKPKKEK 528
            ||:|....:.|.|.:.            |:|.|.:|
  Fly   488 VLILALRRIDFPYEKVRSLYSLMAPFITIAKTKSKK 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	120/450 (27%)
Ugt50B3	NP_724417.3	Glycosyltransferase_GTB-type	43..480	CDD:471961	131/459 (29%)