Protein Alignment Ugt37A3 and Ugt2b35

DIOPT Version :9

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_766469.1
• Gene: Ugt2b35 / 243085
• MGIID: 3576100
• Length: 529
• Species: Mus musculus
• Alignment Length: 546
• Identity: 141/546 - (25%)
• Similarity: 253/546 - (46%)
• Gaps: 54/546 - (9%)

  Fly    10 LLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKPVVNHKNITVI 74
            ||.:.:.....|:....:| ::| |..||.:........|.:.||.   ||||:|..:      |
Mouse     9 LLLLQMSCCFRSTSCGKVL-VWP-LEFSHWMNLKIILDELVQRGHE---VTVLRPSAS------I 62

  Fly    75 QVPLSKEEAQQMSDTIGAMSKNDNSNMALSLLRMSDQMDFMIRKNA-------ETLMNDRVRDLY 132
            .|........:......|.||:   .:...|.::.|:..|.:.::.       :||.. ::.|..
Mouse    63 FVDPKYSPGLKFETFPTAFSKD---YLETFLTKLVDEWTFEVPRDTCLSYSLLQTLFG-KLSDYS 123

  Fly   133 LN---------------RGNKFDLVISGYFMNDFQLGFARKVNAPVIVLATMPPNHLLNPLIGN- 181
            |:               :.:|||::|.....:..:| .|:.:..|.:......|.:.:....|.
Mouse   124 LSLCKEAVSNKQLMTKFQESKFDVLILDAMASCGEL-IAQLLQIPFLYSLRFSPGYQVEKNSGGF 187

  Fly   182 PLEVSYAGISNPAEGSKAVTFQRRLSSYMQSLGFGV-FSHLSERRNRNWYKEVYGNDPKMPEYSE 245
            .|..||..:.....|.: :||..|:.:.:..|.|.. |...:|:....:|.|..|....:   .|
Mouse   188 VLPPSYVPVILSGLGGQ-MTFTERVKNMICMLYFDFWFQTFTEKEWDQFYSETLGRPTTL---IE 248

  Fly   246 MLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFL-GNATDGAILLSLGS 309
            .:....:.|..|:...|.| .|.:|:...:||:..| ...|||:.:.:|: .:...|.::.||||
Mouse   249 TMGKAEMWFIRSYWDLEFP-HPTLPNVEYVGGLHCK-PAKPLPKEMEDFVQSSGVHGVVVFSLGS 311

  Fly   310 NVQGKHLNPDTVAKMFNVLSKLKERVIWKWEDQENTPGK-SANILYSKWLPQDDILAHPNIKLFI 373
            .|  .::..:....:...|:::.::|:|:::.:  ||.. ..|....|||||:|:|.||..|.|:
Mouse   312 MV--SNMTEERANAISWALAQIPQKVLWRFDGK--TPASLGPNTRIYKWLPQNDLLGHPKTKAFV 372

  Fly   374 NHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILEILSNPQ 438
            .|.|..|:.|:.:||.||:.:|:|::|..|...||..|..:.|::.|:.......|:.|:::||.
Mouse   373 THGGANGLYEAIHHGIPMIGIPLFSEQHDNIAHMVAKGTAVALNIRTMSRSDLLNALEEVINNPS 437

  Fly   439 YAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVH-MSFIAANNIDICFLIFVIL 502
            |.|.|...||::.|:||......::|.|:|:||.||.||: ||.| :::...:::|:...:.|.:
Mouse   438 YKENVMWLSTIHHDQPMKPLNRTIFWIEFVMRHKGAKHLR-PLAHNLTWYQYHSLDVIGFLLVCV 501

  Fly   503 VSVLVLIKFLVQFIYRRFISKPKKEK 528
            |:..||......|:|:.|:.|.||.|
Mouse   502 VATAVLPVKCCLFVYQFFVKKAKKRK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	egt	1..490	CDD:223071	129/506 (25%)
		UDPGT	37..526	CDD:278624	132/515 (26%)
Ugt2b35	NP_766469.1	egt	8..506	CDD:223071	132/523 (25%)
		UDPGT	24..525	CDD:278624	135/527 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840528
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840