Protein Alignment Ugt37A3 and Ugt3a1

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_659094.1
• Gene: Ugt3a1 / 223337
• MGIID: 2145969
• Length: 523
• Species: Mus musculus
• Alignment Length: 574
• Identity: 150/574 - (26%)
• Similarity: 254/574 - (44%)
• Gaps: 117/574 - (20%)

  Fly     8 FLLLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKPVVNHKNI- 71
            ||.|.:.:      .:.|.||.: .:||.||.|:....::||.|.|||||     |.:....||
Mouse    12 FLFLEVIL------LEAAKILTI-STLSASHYIVISRVSQVLHEGGHNVT-----KLLYESANIP 64

  Fly    72 ---------TVIQVPLSKEEAQQMSD---------TIGAMSKNDN--------SNMALSLLRMSD 110
                     .||.....:::.::.:|         |.| .||:..        .::...||...|
Mouse    65 DFRKEKPSYQVINWRPPEDQEKKFADLRHRLTEEITYG-RSKHHTLLKIHQYFGDLCSQLLSRKD 128

  Fly   111 QMDFMIRKNAETLMNDRVRDLYLNRGNKFDLVISGYFMNDFQLGFARKVNAPVIVLATMPPNHLL 175
            .|||:..:|                   ||||:.. .|:...|....|:....:.......:::.
Mouse   129 IMDFLKNEN-------------------FDLVLLD-SMDLCSLLIVEKLGKRFVSFLPFQFSYMD 173

  Fly   176 NPLIGNPLEVSYAGISNPAEGS---KAVTFQRRLSSYMQSLGFGVFSHLSERRNRNWYKE----- 232
            ..|...||  |||    |..||   ..:.|..|:.:::..|.|.    :.:|...:.|..
Mouse   174 FGLPSAPL--SYA----PVYGSGLTDQMDFWGRVKNFLMFLDFS----MKQREILSQYDSTIQEH 228

  Fly   233 -VYGNDPKMPEYSEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKP-DPLPQNIAEFL 295
             |.|:.|.:   |::|....|.|.:|..|.:. .||..|:.:.:||  :.||| .|:||::..|:
Mouse   229 FVEGSQPVL---SDLLLKAELWFVNSDFALDF-ARPLFPNTVYVGG--LLDKPVQPIPQDLENFI 287

  Fly   296 GNATD-GAILLSLG---SNVQGKHLNPDTVAKMFNVLSKLKERVIW-----KW-EDQENTPGKSA 350
            ....| |.:|::||   |.:|.|.:    :.:|.:..:.|.:.|:|     .| :|....|
Mouse   288 SQFGDSGFVLVALGSIVSMIQSKEI----IKEMNSAFAHLPQGVLWTCKTSHWPKDVSLAP---- 344

  Fly   351 NILYSKWLPQDDILAHPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLT 415
            |:....||||.|:||||:|:||:.|.|...:.|:.:||.||:.:|.|.|||.|...:.....|::
Mouse   345 NVKIMDWLPQTDLLAHPSIRLFVTHGGMNSVMEAVHHGVPMVGIPFFFDQPENMVRVEAKNLGVS 409

  Fly   416 LSLLTLEEKPFQEAILEILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHL--- 477
            :.|.||:.:.|...:.:|:.:.:|.....:...:....|:|..:..|.|.:::::..|||||
Mouse   410 IQLQTLKAESFALTMKKIIEDKRYKSAAMASKIIRHSHPLTPAQRLLGWIDHILQTGGAAHLKPY 474

  Fly   478 --QSPLVHMSFIAANNIDI-CFLIFVILVSVLVLIKFLVQFIYRRFISKPKKEK 528
              |.|. |..::    :|: .||:.::|.::.:.:|.||  ...|::|...|.|
Mouse   475 AFQQPW-HEQYM----LDVFLFLLGLMLGTLWLSVKVLV--AVTRYLSIATKVK 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	127/485 (26%)
Ugt3a1	NP_659094.1	Glycosyltransferase_GTB-type	23..488	CDD:471961	136/520 (26%)