Protein Alignment Ugt37A3 and ugt-8

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_504315.1
• Gene: ugt-8 / 186768
• WormBaseID: WBGene00019234
• Length: 531
• Species: Caenorhabditis elegans
• Alignment Length: 555
• Identity: 133/555 - (23%)
• Similarity: 235/555 - (42%)
• Gaps: 77/555 - (13%)

  Fly    10 LLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVV----TVLK---PVVN 67
            ||:|.:  |:||....|||...|....||:......|.::|::|||||:.    ..||   .::.
 Worm     6 LLSILL--VLGSVSCKNILIFNPIFGLSHVKFISKMANIIADHGHNVTLFQPFHIALKNTEGLIK 68

  Fly    68 HKNITVIQVPLSKEEAQQMSDTIGAMSKNDN---SNMALSLLRMSDQMDFMIRKNAETLMNDRVR 129
            :|.|.:|.......:....::|....:..|:   :|..||...:...:.....:.|..|:.|:|.
 Worm    69 NKYIEIINYYPDHYDELLKTETATFPAFWDSHLMNNPVLSAFMIPKAIAGEFERTATQLLKDKVA 133

  Fly   130 --DLYLNRGNKFDLVISGYFMNDFQLG---FARKVNAPVIVLATMPPNHLLNPLIGNPLEVSYAG 189
              ||   :...||::||    ..|:|.   .|..:|.|.|.:.:.....:.|.:.|.|..:.|:
 Worm   134 LDDL---KSRNFDVIIS----ETFELTGMYIAHMLNVPCIPVWSAVRFTIFNNIFGQPSSLGYS- 190

  Fly   190 ISNPAEGSKAVTFQRRLSSYMQSLGFGVFSHLSERRN---RNWYKEV-------YGND------- 237
                         |:..|......||      .:|.|   ||::..:       |.||
 Worm   191 -------------QQPFSKLAPEAGF------IDRLNDVYRNFFFTITMDGMGQYQNDFIEKAVG 236

  Fly   238 PKMPEYSEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGG----IQIKDKPDPLPQNIAEFLGNA 298
            ..:|.:.:::|...:.|.:|:...:..: |...:.:.|||    ::.....||||...|:.| ..
 Worm   237 RPLPYWKDLIKEAPVYFTNSNEYLDFAV-PTTATIVHIGGFTMDLEKMKHVDPLPDKYAKIL-EE 299

  Fly   299 TDGAILLSLGSNVQGKHLNPDT----VAKMFNVLSKLKERVIWKWE--DQENTPGKSANILYSKW 357
            .:..:|:|.||.::...: ||.    :.|||..|..:  ..|||:|  |.|.......|:...||
 Worm   300 RESTVLISFGSVIRSYQM-PDNFKAGIIKMFESLPDV--TFIWKYERDDVEFQKKLPKNVHLKKW 361

  Fly   358 LPQDDILAHPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLE 422
            :||..:||...:|||:.|.|.|...|..|.|||.|.:|:|.|||.|||.:.:.|..::.....|.
 Worm   362 VPQHSLLADNRVKLFVTHGGLGSTMEVAYTGKPALMVPIFGDQPENANMLARHGGAISYDKFELA 426

  Fly   423 E-KPFQEAILEILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMSF 486
            : :.....|.:::.||:|.:..:....:...:|:..:.:.:...|:.:...........:..|..
 Worm   427 DGEKLAITIRDMVRNPKYNKNAQELLKVLSHQPIDPKLNLMKHLEFAMEFPNLRSQVPAINQMGL 491

  Fly   487 IAANNIDICFLIFVILVSVLVLIKFLVQFIYRRFI 521
            ||...:|:.|.:.:|.:..:.|...::..:..|.:
 Worm   492 IAHYYLDVIFFLSLIFILTVYLTFKIISLLPIRIV 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	118/481 (25%)
ugt-8	NP_504315.1	GT1_Gtf-like	20..457	CDD:340817	117/468 (25%)