Protein Alignment Ugt37A3 and ugt-61

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_504274.2
• Gene: ugt-61 / 185500
• WormBaseID: WBGene00018206
• Length: 530
• Species: Caenorhabditis elegans
• Alignment Length: 553
• Identity: 138/553 - (24%)
• Similarity: 242/553 - (43%)
• Gaps: 72/553 - (13%)

  Fly     2 VLRVEKFLLLAIAIGAVMGSSQGANILGLF-PSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKPV 65
            ||.|  ||:|   :|.|     .|....|| |:::.|.:......|:|||..||:||::     :
 Worm     3 VLSV--FLVL---VGVV-----SAYKFVLFVPNVANSQIQFNARVAEVLAIGGHDVTML-----M 52

  Fly    66 VNH-----------KNITVIQVPLSKEEAQQMSDTIGAMSKNDNSNMALSLLRMSD--QMDFMIR 117
            |||           |.:...|:..:.|...:.|      .:.:.|.|....:.:.|  ||..|..
 Worm    53 VNHMAGFESNVKVPKGVKTYQLDAAVEGITKQS------IEKEQSAMLYKNMGLKDMPQMMAMFS 111

  Fly   118 KNAETLMNDRVRDLYLNR-------GNKFDLVISGYFMNDFQLGFARKVNAPVIV-LATMPPNHL 174
            :..: |:.|..|.:..|:       ..|||:..: :..:...||.......|..| |.:.|....
 Worm   112 RMGK-LLQDGCRIILRNKEFLKWLEDEKFDVAYT-HIYSTCPLGLIHHAKIPSWVWLNSGPLMDY 174

  Fly   175 LNPLIGNPLEVSYAG----ISNPAEGSKAVTFQRRLSSYMQSLGFGVFSH--LSERRNRNWYKEV 233
            ::..:|.|:..||..    .|:...|     |.:|..|::..:...|...  .|:.....:.||:
 Worm   175 VSQAVGVPILPSYVPPVLMASHDEMG-----FVQRTKSFIGHVLMSVMHRRISSDEETAIFRKEL 234

  Fly   234 YGNDPKMPEYSEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIK-DKPDPLPQNIAEF--L 295
              |||..|...::.....||..:|:...:.| ||.:...|.|||:.:. |...||   ..||  :
 Worm   235 --NDPSFPHTMDIGAKCPLVIVNSNELYDLP-RPTLAKVINIGGLGVGFDSAKPL---TGEFKKI 293

  Fly   296 GNATDGAILLSLGSNVQGKHLNP----DTVAKMFNVLSKLKERVIWKWEDQENTPGKSANILYSK 356
            ....:|.|:.|.|| |...|..|    :::.:.|..|...  :.:.::|..:.......|:..||
 Worm   294 SETGNGLIVFSFGS-VAAAHEMPLAWKNSLLEAFASLPDY--QFVMRYEGDDLKDRLPENVHLSK 355

  Fly   357 WLPQDDILAHPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTL 421
            ||||.|:|.|...|.||.|.|...:.|:...|.|::::.:..|||:|:....|.||.:.:...|:
 Worm   356 WLPQKDLLLHEKTKAFITHGGYNSLQEAISAGVPLITIALMGDQPKNSQIAKKHGFAVNIEKGTI 420

  Fly   422 EEKPFQEAILEILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMSF 486
            .::...||:.|||.|..|.::|...|.:.|.:||...|..|.|:|::.......:|......::|
 Worm   421 SKETVVEALREILENDSYKQKVTRLSAMVRAQPMKPAERLLKWSEFLAEFKTLDNLVPAGQKLNF 485

  Fly   487 IAANNIDICFLIFVILVSVLVLIKFLVQFIYRR 519
            ...:::|:...:|::::.|..:...:::.::|:
 Worm   486 YQYHSLDVIGFLFLVVLVVFYIGFLILKAVFRK 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	122/473 (26%)
ugt-61	NP_504274.2	Glycosyltransferase_GTB-type	37..519	CDD:471961	125/509 (25%)