Protein Alignment Ugt37A3 and ugt-2

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_505672.2
• Gene: ugt-2 / 179450
• WormBaseID: WBGene00007073
• Length: 531
• Species: Caenorhabditis elegans
• Alignment Length: 568
• Identity: 155/568 - (27%)
• Similarity: 250/568 - (44%)
• Gaps: 85/568 - (14%)

  Fly     7 KFLLLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVV-TVLKP------ 64
            |..||.....|:..:....|.|.:.|....||:......|..||...||||:: |.:..
 Worm     2 KLFLLVFLFFALYCNVLAYNYLVVAPVFGYSHMKFMNKVADTLANGKHNVTLLQTYIYEHWGKIR 66

  Fly    65 VVNHKNITVI------QVPLSKEEAQQM----------SDTIGAMSKNDNSNMALSLLRMSDQMD 113
            :|.:|||.:|      .||.:::.|...          :...|||:                  .
 Worm    67 IVKNKNIEIIDYHNSENVPSNEQSASAFKFFWDNEIVNNPITGAMA------------------P 113

  Fly   114 FMIRKNAETLMNDRV-RDLYLNR---GNKFDLVISGYFMNDFQ-----LGFARKVN-APVI-VLA 167
            ..|..|....|.||: .|..|::   .||||    ||....|.     ||...|:| .|:. .:.
 Worm   114 MFILYNEFKPMCDRILTDKELHQWILSNKFD----GYVAESFDFCSLYLGDHLKLNLLPMFSTIK 174

  Fly   168 TMPPNHLLNPLIGNPLEVSYAGISNPAEGSKAVTFQR-----RLSSYMQSLGFGVFSHLSERRNR 227
            .:|.:|    .||.|..::||.......||....:.|     ..:|:..:     ||:|.||:.|
 Worm   175 NVPGSH----AIGEPSLLNYAPSLYTNFGSDQTVWDRIQDITAFTSFHYA-----FSNLFERQYR 230

  Fly   228 NWYKEVYGNDPKMPEYSEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIA 292
            ..|..:.|:   :..:.|:|: |:..||.::....|...|.:..::||||..| |.|..|..| .
 Worm   231 QAYDLLNGD---VRTWREILQ-TATYFFYNNNPYIGFAMPTLEKSVEIGGFTI-DPPHDLSLN-E 289

  Fly   293 EF--LGNATDGAILLSLGSNVQGKHLNPDTVAKMFNVLSKLKERV-IWKW--EDQENTPGKSANI 352
            ||  |.:.....:|:|.|:.||...:..:..:.:..:.:||.:.. |||:  ||.|.:...|.|:
 Worm   290 EFDKLLDLRKSTVLISFGTVVQSADMPENFKSGLIKMFAKLPDTTFIWKYEVEDAEFSKTLSENV 354

  Fly   353 LYSKWLPQDDILAHPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLS 417
            ...||:||..:||.|.:.|||.|.|.|...|..|.|||.|.:|:|.||..||..:.:.|..::..
 Worm   355 FLKKWIPQPALLADPRLNLFITHGGLGSTLEVAYAGKPSLMIPIFGDQMLNAKMLSRHGGAISYD 419

  Fly   418 LLTLEE-KPFQEAILEILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPL 481
            ...||. :...|.:.|.:||.:|.::....:.:..::|:..:::.|...|:..: .|..|...|.
 Worm   420 KYELENYEKLTETVKEAISNKEYNKKALLLAEILHNQPIDPKQNLLKHAEFTAK-FGRVHALEPY 483

  Fly   482 -VHMSFIAANNIDICFLIFVILVSVLVLIKFLVQFIYRR-FISKPKKE 527
             ||.:||....:|...:|.:..:|:|.::..:::|:||: |.||.|.|
 Worm   484 SVHYNFIKYYMLDAYAIIIIFFLSILYVLNLIIKFVYRKIFKSKRKTE 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	131/483 (27%)
ugt-2	NP_505672.2	GT1_Gtf-like	24..453	CDD:340817	127/465 (27%)