Protein Alignment Ugt37A3 and ugt-12

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_504309.1
• Gene: ugt-12 / 178880
• WormBaseID: WBGene00020592
• Length: 534
• Species: Caenorhabditis elegans
• Alignment Length: 563
• Identity: 135/563 - (23%)
• Similarity: 253/563 - (44%)
• Gaps: 68/563 - (12%)

  Fly     3 LRVEKFLLLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTV-------VT 60
            :|:..|:.|...:.....||:   ||...|....||:......|.::|::||:||:       :.
 Worm     1 MRLGTFIFLLTFLFFECYSSK---ILIFNPIFGFSHVKFISKMADIIADHGHHVTLFQPYHIALK 62

  Fly    61 VLKPVVNHKNITVIQV------PLSKEEAQQMS---DT--IGAMSKNDNSNMALSLLRMSDQMDF 114
            .|..:|.:|||.::..      .|.|.|.|..|   |:  :|        |..:....|...:..
 Worm    63 NLDGLVKNKNIEILNYHPTHYEELLKAEPQTFSFFWDSYLVG--------NPVIGAFLMPKLLGG 119

  Fly   115 MIRKNAETLMNDR--VRDLYLNRGNKFDLVISGYF-MNDFQLGFARKVNAPVIVLATMPPNHLLN 176
            ..:|.|..:::|:  :.:|   :..||||||:..| :..|.|  |..::.|.|.:.:.....:.|
 Worm   120 EFKKTAMEVLSDQKLINEL---KDRKFDLVIAETFELTGFYL--AHLLDVPCIPMMSAVRYPIFN 179

  Fly   177 PLIGNPLEVSYAGISNPAEGSKAVT----FQRRLSSYMQSLGFGVFSHLSERRNRNWYKEVYGND 237
            ...|.|..:.:.    |..|| ||.    |..||:...:....|:......:....:.:|..|.
 Worm   180 DQFGQPSLLGHV----PQIGS-AVAGEAGFYDRLNDMFRFFFMGISQEQLNKYQNYFIEEAIGR- 238

  Fly   238 PKMPEYSEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKP----DPLPQNIAEFLGNA 298
             .:|.:.:::|.:.:...:|:...:..: |:..:.:::|||.:..|.    ..||:.....| ..
 Worm   239 -PVPFWKDLVKQSPIYITNSNPYLDYAV-PSTAAIVQVGGITMDLKKLKQVGELPEEYENIL-KE 300

  Fly   299 TDGAILLSLGSNVQGKHLNPDTVAKMFNVLSKLKE-RVIWKWE--DQENTPGKSANILYSKWLPQ 360
            .:..:|:|.||.::...:.....|.:..|...|.: ..|||:|  |.|.......|:...||:||
 Worm   301 RESTVLISFGSVIRSYEMPESFKAGLIKVFESLPDVTFIWKYEKDDLEFQKRLPKNVHLKKWIPQ 365

  Fly   361 DDILAHPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKP 425
            ..:||...:||||.|.|.|...|..|.|||.:.:|:|.||..||..:.:.|..:......|:...
 Worm   366 PSLLADKRVKLFITHGGLGSTMEVAYTGKPAIVVPIFGDQHHNAVMLARHGGAVAYDKFDLKNGE 430

  Fly   426 FQEAIL-EILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIR--HHGAAHLQSPLVH-MSF 486
            ...|:: |::|:.:|.|..::...:..::|:..:.:||...::.|:  :|.|   |.|.:: :.|
 Worm   431 KLTAVVHEMISSTKYQENAEALQHVLFNQPIDPKMNFLNHLDFAIKFPNHRA---QVPAINQLGF 492

  Fly   487 IAANNIDICFLIFVILVSVLVLIKFLVQFIYRRFISKPKKEKT 529
            :|...:|:  |:|:::.|  ::|.:|...:.::.:.|...:||
 Worm   493 VAHYYLDV--LLFLLVSS--IVITYLAISLLKKVLGKCLTKKT 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	114/471 (24%)
ugt-12	NP_504309.1	GT1_Gtf-like	21..456	CDD:340817	111/459 (24%)