Protein Alignment Ugt37A3 and UGT3A1

DIOPT Version :9

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_689617.3
• Gene: UGT3A1 / 133688
• HGNCID: 26625
• Length: 523
• Species: Homo sapiens
• Alignment Length: 562
• Identity: 143/562 - (25%)
• Similarity: 254/562 - (45%)
• Gaps: 87/562 - (15%)

  Fly     9 LLLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKPVVNHKNITV 73
            ||:|..:..|: .|:.|.||.: .:|..||.::....:::|.|:|||||::        |::...
Human     8 LLVAFLLSGVL-LSEAAKILTI-STLGGSHYLLLDRVSQILQEHGHNVTML--------HQSGKF 62

  Fly    74 IQVPLSKEEAQQMSDTIGAMSKNDNSNMALSLLRMSDQMDFMI------RKNAETLMNDRVRDLY 132
            : :|..||| ::....|...|..|:..      |:....|..|      ||.:|.|:  ::.:::
Human    63 L-IPDIKEE-EKSYQVIRWFSPEDHQK------RIKKHFDSYIETALDGRKESEALV--KLMEIF 117

  Fly   133 -------LNR--------GNKFDLVISGYFMNDF-QLGFARKVNAPVIVLATMPPNHLLNPLIGN 181
                   |:|        ...:|||....|  || ....|.|:..|.:.:.   |....:...|.
Human   118 GTQCSYLLSRKDIMDSLKNENYDLVFVEAF--DFCSFLIAEKLVKPFVAIL---PTTFGSLDFGL 177

  Fly   182 PLEVSYAGISNPAEGSKAVTFQRRLSSYMQSLGFGVFSHLSERRNRNWYKEVYGNDPKMPEYSEM 246
            |..:||..:. |:..:..:.|..|:.:::....|.......:....|..||.:....: |..|.:
Human   178 PSPLSYVPVF-PSLLTDHMDFWGRVKNFLMFFSFSRSQWDMQSTFDNTIKEHFPEGSR-PVLSHL 240

  Fly   247 LKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKP-DPLPQNIAEFLGNATD-GAILLSLGS 309
            |....|.|.:|..|.:. .||.:|:.:.|||:.  :|| .|:||::..|:.|..| |.:|::.||
Human   241 LLKAELWFVNSDFAFDF-ARPLLPNTVYIGGLM--EKPIKPVPQDLDNFIANFGDAGFVLVAFGS 302

  Fly   310 NVQGKHLNPDTVAKMFNVLSKLKERVIW-----KWEDQENTPGKSANILYSKWLPQDDILAHPNI 369
             :...|.:.:.:.||.|..:.|.:.|||     .|....:.   :.|:....||||.|:||||:|
Human   303 -MLNTHQSQEVLKKMHNAFAHLPQGVIWTCQSSHWPRDVHL---ATNVKIVDWLPQSDLLAHPSI 363

  Fly   370 KLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSL-------LTLEEKPFQ 427
            :||:.|.|:..:.|:..||.||:.|||..||..|...:|...:|:::.|       |||..|
Human   364 RLFVTHGGQNSVMEAIRHGVPMVGLPVNGDQHGNMVRVVAKNYGVSIRLNQVTADTLTLTMK--- 425

  Fly   428 EAILEILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHL-----QSPLVHMSFI 487
                :::.:.:|...|.:.|.:...:|::..:..:.|.:::::..||.||     |.|. |..::
Human   426 ----QVIEDKRYKSAVVAASVILHSQPLSPAQRLVGWIDHILQTGGATHLKPYAFQQPW-HEQYL 485

  Fly   488 AANNIDICFLIFVILVSVLVLIKFLVQFIYRRFISKPKKEKT 529
                ||:...:..:.:..:.|...|:..:.|......|.:||
Human   486 ----IDVFVFLLGLTLGTMWLCGKLLGVVARWLRGARKVKKT 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	egt	1..490	CDD:223071	135/521 (26%)
		UDPGT	37..526	CDD:278624	131/529 (25%)
UGT3A1	NP_689617.3	UDPGT	23..523	CDD:330975	136/544 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150079
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840