Protein Alignment Ugt37A3 and UGT2B11

DIOPT Version :9

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001064.1
• Gene: UGT2B11 / 10720
• HGNCID: 12545
• Length: 529
• Species: Homo sapiens
• Alignment Length: 552
• Identity: 137/552 - (24%)
• Similarity: 238/552 - (43%)
• Gaps: 113/552 - (20%)

  Fly    44 SAAKVL---AENGHNVTVVTVLKPVVNH-KNITVI----QVPLSKEEAQQMSDTI--GAMSKNDN 98
            |..|||   ||..|.:.:.|:||.:|.. ..:||:    .:.....:|..:...:  .:::|.:.
Human    22 SCGKVLVWAAEYSHWMNMKTILKELVQRGHEVTVLASSASILFDPNDASTLKFEVYPTSLTKTEF 86

  Fly    99 SNMAL-SLLRMSDQMDFMIRKNAETLMNDR-------VRDLYLN---------------RGNKFD 140
            .|:.: .:.|.||     |||::..|...:       :.|::.|               :.::||
Human    87 ENIIMQQVKRWSD-----IRKDSFWLYFSQEQEILWELYDIFRNFCKDVVSNKKVMKKLQESRFD 146

  Fly   141 LVISGYFMNDFQLGFARKVNAPVIVLATMPPNHLLNPLI------------GNPLEVSYAGISNP 193
            :|.:.                     |..|...||..|:            |..:|....|:..|
Human   147 IVFAD---------------------AVFPCGELLAALLNIRFVYSLRFTPGYTIERHSGGLIFP 190

  Fly   194 --------AEGSKAVTFQRRLSSYMQSLGFGVFSHLSERRNRNW---YKEVYGND----PKMPEY 243
                    ::.|..:||..|:.:.:..|.|..:..:|:.  :.|   |.||.|..    ..|.:.
Human   191 PSYIPIVMSKLSDQMTFMERVKNMIYVLYFDFWFQMSDM--KKWDQFYSEVLGRPTTLFETMGKA 253

  Fly   244 SEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFL-GNATDGAILLSL 307
            ...|...|..|...|     |..|||..   :||...| ...|||:.:.||: .:..:|.::.||
Human   254 DIWLMRNSWSFQFPH-----PFLPNVDF---VGGFHCK-PAKPLPKEMEEFVQSSGENGVVVFSL 309

  Fly   308 GSNVQGKHLNPDTVAKMFNV----LSKLKERVIWKWEDQENTP-GKSANILYSKWLPQDDILAHP 367
            ||.:.      :..|:..||    |:|:.::|:|:::.  |.| ....|....||:||:|:|.||
Human   310 GSVIS------NMTAERANVIATALAKIPQKVLWRFDG--NKPDALGLNTRLYKWIPQNDLLGHP 366

  Fly   368 NIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILE 432
            ..:.||.|.|..||.|:.|||.||:.:|:|.|||.|...|...|..:.|...|:.......|:..
Human   367 KTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAAVRLDFNTMSSTDLLNALKT 431

  Fly   433 ILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDIC-F 496
            ::::|.|.|.:...|.:..|:|:...:..::|.|:|:.|.||.||:.....:::...:::|:. |
Human   432 VINDPLYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMPHKGAKHLRVAAHDLTWFQYHSLDVIGF 496

  Fly   497 LIFVILVSVLVLIKFLVQFIYRRFISKPKKEK 528
            |:..:...:.::.||.: |.:.:|..|.||.|
Human   497 LLACVATVIFIITKFCL-FCFWKFARKGKKGK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	egt	1..490	CDD:223071	126/511 (25%)
		UDPGT	37..526	CDD:278624	134/548 (24%)
UGT2B11	NP_001064.1	UDPGT	24..525	CDD:278624	133/546 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150530
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840