Protein Alignment Ugt37A3 and ugt1a1

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: XP_004917944.1
• Gene: ugt1a1 / 100489505
• XenbaseID: XB-GENE-998849
• Length: 532
• Species: Xenopus tropicalis
• Alignment Length: 537
• Identity: 133/537 - (24%)
• Similarity: 243/537 - (45%)
• Gaps: 88/537 - (16%)

  Fly    34 LSPSHLIIQMSAAKVLAENGHNVTVVTVLKPVVNHKNITV----------IQVPLSKE--EAQQM 86
            |..||.:......:.|.:.|:.   |.||.|   |.||.:          ..||.|||  :.|.:
 Frog    36 LDGSHWLSMRILVESLGQRGNQ---VVVLAP---HSNIHIHPSENYILRTYPVPYSKELLKEQMV 94

  Fly    87 SDTIGAMSKNDNSNMALSLLRMSDQMDFMIRKNAETLMNDR--VRDLYLNRGNKFDLVISGYFMN 149
            .......:|....:...::.:....:..::....:.|::.:  :::|   :.:.||..:...|
 Frog    95 KSANDVFTKRPLLDKITNMYQRITNVTGIVFSACQHLLHSKEIMQEL---QESAFDAALIDPF-- 154

  Fly   150 DFQLGF--ARKVNAPVIVLATMPPNHLLNPLIGNPLEVSYAGISNPAE----------GSKAVTF 202
             |..|.  |..::.|.:.|           |.|.|..:.......|:.          .:..::|
 Frog   155 -FPCGMIVAEYLHLPSVYL-----------LYGLPCGIDRLATQCPSPLSYVPRHFTGNTDHMSF 207

  Fly   203 QRRL--------SSYMQSLGFGVFSHL-SERRNRNW-YKEVYGNDPKMPEYSEMLKNTSLVFFSS 257
            .:||        .:::.:|.:..::.| ||..:|.. ..::|.      :.|..|..|..||
 Frog   208 PQRLKNALLWPVDTFLCNLLYSPYAQLASEFLHREMTILQLYS------QTSVWLMKTDFVF--- 263

  Fly   258 HAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFLGNATD-GAILLSLGSNVQGKHLNPDTV 321
                :.| ||.:|:.:.:|||....: ..|.|...:.:.::.: |.::.||||.|....:|
 Frog   264 ----DYP-RPLMPNMVFVGGINCVGE-QHLNQEFEKLVNSSGEHGFVVFSLGSMVSEIPMN---- 318

  Fly   322 AKMFNVLSKLK---ERVIWKWEDQENTPGKSANILYSKWLPQDDILAHPNIKLFINHAGKGGITE 383
             |..::...||   ::|.|::..:. .|....|....|||||:|:||||..:.||.|||..||.|
 Frog   319 -KAMDIAEALKSIPQKVFWRYTGKA-PPNLGENTHLVKWLPQNDLLAHPKARAFITHAGSHGIYE 381

  Fly   384 SQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILEILSNPQYAERVKSFST 448
            ...:..||:.:|:|.||..||..:...|.||||::|.:..:....|:..:::||.|.|.::..|:
 Frog   382 GICNAVPMVMMPLFGDQMDNAKRIESRGAGLTLNVLHMTPEDLSNAVRAVINNPVYKENIQRMSS 446

  Fly   449 LYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVH-MSFIAANNIDIC-FLIFVILVSVLVLIKF 511
            |:.|||:...:..::|.|:|:||.||.||: |..| :::....::|:. ||:.|:|.::.:.:|
 Frog   447 LHLDRPIHPLDLAVHWVEFVMRHKGAPHLR-PAAHDLNWFQYYSLDVIGFLLAVLLTALFISLK- 509

  Fly   512 LVQFIYRRFISKPKKEK 528
            ...|::||...:..|::
 Frog   510 CCTFVFRRCFKRNSKKQ 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	112/469 (24%)
ugt1a1	XP_004917944.1	UDPGT	30..525	CDD:278624	132/534 (25%)