Protein Alignment Ugt37A3 and ugt1b5

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001170813.1
• Gene: ugt1b5 / 100384899
• ZFINID: ZDB-GENE-080227-14
• Length: 528
• Species: Danio rerio
• Alignment Length: 554
• Identity: 137/554 - (24%)
• Similarity: 253/554 - (45%)
• Gaps: 69/554 - (12%)

  Fly     9 LLLAIAIGAVMGS--SQGANILG--LFPSLSPSHLIIQMSAAKVLAENGHNVTVVTV-----LKP 64
            |::.:...|.|..  |:.::..|  |...:..||.....:.|:.:...||.|.||..     |.|
Zfish     8 LVVGVVCSAAMNQKPSRNSSWTGKLLVVPMDGSHWTGVKAVAEEMGRRGHTVIVVIPEISMRLGP 72

  Fly    65 VVNH--KNITVIQVP-LSKEEAQQMSDTIGAMSKNDNSNMALSLLRMSDQMDFMIRKNAETLMND 126
            ..::  |...|...| :..:...::.:|:.|..::....:..::......:|:.| ...|:|..:
Zfish    73 GKHYITKKFPVKYKPDVLNQMIAKLVNTLSAPEQSLLKRVTSNIYNFGKVVDYFI-STTESLFQE 136

  Fly   127 RVRDLYLNRGNKFDLVISGYFMNDFQLGFARKVNAPVIVL---------ATM---PPNHLLNPLI 179
            :....:| |...||.|::...|....: .|..::.|.:.:         ||.   ||:::.....
Zfish   137 QELIEFL-RDQNFDAVLTDPAMPTGAI-LAYNLSVPAVYMLRGLMCESKATACPDPPSYIPRLFT 199

  Fly   180 GNPLEVSYAGISNPAEGSKAVTFQRRLSSYMQSLGFGV-----FSHLSERRNRNWYKEVYGNDPK 239
            .|               |..:.|..||.:.:.||...:     ||...|..::..:::|
Zfish   200 QN---------------SDHMNFGERLMNTLASLMEPLMCKLKFSAFEEVTSKFLHRDV------ 243

  Fly   240 MPEYSEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFL-GNATDGAI 303
              ..:|:|...::.........|.| :|.:|:...||||.. :..:||.:.:.||: |:...|.:
Zfish   244 --SMTEILSTGAVWLMRYDFTLEFP-KPLMPNITNIGGINC-EVNNPLTKEVEEFVNGSGEHGIV 304

  Fly   304 LLSLGSNVQGKHLNPDTVAKM-FNVLSKLKERVIWKW--EDQENTPGKSANILYSKWLPQDDILA 365
            :.||||.|...   |...|.: |...|.:.:||:|::  |...|.|   .|:...|||||:|:|.
Zfish   305 VFSLGSLVSSM---PKEKADIFFKAFSMIPQRVLWRYTGEIPNNVP---ENVKLMKWLPQNDLLG 363

  Fly   366 HPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAI 430
            ||..:.||.|.|..||.|...||.||:.||:|.||..|.:.:...|.|:.||:..:..:...:|:
Zfish   364 HPKARAFITHGGTHGIYEGICHGVPMVMLPLFGDQADNVHRVATRGVGVILSIHDITVETLLDAL 428

  Fly   431 LEILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDIC 495
            ..:::|..|.::::..|.::.|||:...:..::|||:|:||.||.||:.....::::..:::|:.
Zfish   429 NSVINNSSYKQKMQKLSAIHNDRPIQPLDLAVFWTEFVMRHKGADHLRPAAHELNWLQYHSLDVI 493

  Fly   496 -FLIFVILVSVLVLIKFLVQFIYRRFISKPKKEK 528
             |::.::|:..|.::| .....:||...|.:|.|
Zfish   494 GFMLLIVLIVTLAMLK-CCSLCWRRCCRKTQKRK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	113/469 (24%)
ugt1b5	NP_001170813.1	UDPGT	30..524	CDD:278624	131/528 (25%)