Protein Alignment Ugt37A3 and ugt1b2

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001170807.1
• Gene: ugt1b2 / 100384893
• ZFINID: ZDB-GENE-080227-11
• Length: 531
• Species: Danio rerio
• Alignment Length: 561
• Identity: 141/561 - (25%)
• Similarity: 257/561 - (45%)
• Gaps: 77/561 - (13%)

  Fly     9 LLLAIAIGAVMGS------SQGANILG--LFPSLSPSHLIIQMSAAKVLAENGHNVTVV----TV 61
            ::..:.:|.|..:      |:.::..|  |...:..||.....:.|:.:...||.|.||    :|
Zfish     5 VIFILVVGVVCSAAVDQKPSRKSSWTGKLLVVPMDGSHWTGVKAVAEEMGRRGHTVIVVIPEISV 69

  Fly    62 LKPVVNHKNITVIQVPLSKEEAQQ-MSDTIGAMSKNDNS------NMALSLLRMSDQMDFMIRKN 119
            |.....|....:..|...::...: :::.:..::...||      .:..:|.||.:.|    ...
Zfish    70 LLGPGQHYITKMFSVKYDQKSLNKVLNERVLEVTNPGNSFLSTVIRIVSNLRRMFNTM----AAT 130

  Fly   120 AETLMNDR--VRDLYLNRGNKFDLVISGYFMNDFQLGFARKVNAPVI----VLA---TMPPNHLL 175
            :|:|..|:  :..|   |...||.|::.                ||:    :||   ::|..:||
Zfish   131 SESLFQDKELIESL---RNENFDAVLTD----------------PVLPMGAILAYNLSVPAVYLL 176

  Fly   176 NPLIGNPLEVSYAGISNPAEGSKAVTFQRRLSSYMQSLGFGVFSHLSERRNRNWYKEVYGNDPKM 240
            ..:... |:.:.....||:  |....|..|.:..| |.|..|.:.|.....:...|.:|.:..:|
Zfish   177 RGMACG-LDATATTCPNPS--SYIPRFHTRNTDRM-SFGERVMNMLMSILEQTVCKFMYRSFEEM 237

  Fly   241 --------PEYSEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFL-G 296
                    ...:|:|:..::.........|.| :|.:|:...||||....: :||.:.:.||: |
Zfish   238 IFNFLQRDVSMTEILRTGAVWLMRYDFTLEFP-KPLMPNMQFIGGINCGVR-NPLTKEVEEFVNG 300

  Fly   297 NATDGAILLSLGSNVQGKHLNPDTVAKM-FNVLSKLKERVIWKW--EDQENTPGKSANILYSKWL 358
            :...|.::.||||.|...   |...|.: |...|.:.:||:|::  |...|.|   .|:...|||
Zfish   301 SGEHGIVVFSLGSLVSSM---PKEKADIFFKAFSMIPQRVLWRYTGEIPNNVP---ENVKLMKWL 359

  Fly   359 PQDDILAHPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEE 423
            ||:|:|.||..:.||.|.|..||.|...||.||:.||:|.||..|.:.:...|.|:.||:..:..
Zfish   360 PQNDLLGHPKARAFITHGGTHGIYEGICHGVPMVMLPLFGDQADNVHRVATRGVGVILSIHDITV 424

  Fly   424 KPFQEAILEILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMSFIA 488
            :...:|:..:::|..|.::::..|.::.|||:...:..::|||:|:||.||.||:.....::::.
Zfish   425 ETLLDALNSVINNSSYKQKMQKLSAIHNDRPIQPLDLAVFWTEFVMRHKGADHLRPAAHELNWLQ 489

  Fly   489 ANNIDIC-FLIFVILVSVLVLIKFLVQFIYRRFISKPKKEK 528
            .:::|:. |::.::|:..|.::| .....:||...|.:|.|
Zfish   490 YHSLDVIGFMLLIVLIVTLAMLK-CCSLCWRRCCRKTQKRK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	118/472 (25%)
ugt1b2	NP_001170807.1	UDPGT	31..527	CDD:278624	136/531 (26%)