Protein Alignment Ugt37A3 and ugt1a6

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001107366.1
• Gene: ugt1a6 / 100135191
• XenbaseID: XB-GENE-5793241
• Length: 531
• Species: Xenopus tropicalis
• Alignment Length: 564
• Identity: 138/564 - (24%)
• Similarity: 245/564 - (43%)
• Gaps: 97/564 - (17%)

  Fly     8 FLLLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVV-----TVLKPVVN 67
            |:|||      :|.:.|..:| :.|. ..||.:........||:.||.:.|.     .:.|.:.|
 Frog    17 FILLA------LGCADGGRLL-VVPQ-DGSHWLSMRVLVDRLAQRGHYIVVAIPEVNMLFKDLDN 73

  Fly    68 HKNITVIQVPLSKEEAQQMSDTIGAMSKNDNSNMALSLLRMSDQMDFMIRKNAETLMNDRVRDLY 132
            :| :.....|.||:..:                   :.:|..:|..|:.|     ::.:::...|
 Frog    74 YK-VKTFSSPYSKDVLE-------------------NRMRRMNQEIFVDR-----ILTEKITFWY 113

  Fly   133 LNRGNKFDLVISG--YFMNDFQL-------GFARKVNAPVIVLATMPPNHLLNPLI----GNPLE 184
            .:..|....|:|.  :|:.:..|       .|...:...|.....:...||..|.:    |....
 Frog   114 ESMSNATQWVVSACQHFLQNSTLIRELEKEHFDAMLTDSVFPCGEIVAEHLSIPSVSFMRGTIFG 178

  Fly   185 VSYAGISNPAEGSKA----------VTFQRRLSSYMQSLGFGVFSHLSERRNRNWYKEVYGNDPK 239
            :.......|:..|..          ::|.:|:.:::......:..|:.      :|       |.
 Frog   179 MDQIASQTPSPPSYVPRMFTVYTDNMSFSQRVKNFLIHSLEHIVCHIF------YY-------PY 230

  Fly   240 MPEYSEMLKN--TSLVFFSSHA--------ASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEF 294
            ....|:.||.  |::..||..:        ..|.| ||.:|:.|.||||... |...|||...:.
 Frog   231 AQMASDFLKKEVTAMSLFSRTSIWLMRYDFVFEFP-RPIMPNVILIGGINCA-KQKALPQEFEKL 293

  Fly   295 LGNATD-GAILLSLGSNVQGKHLNPDTVAKMFNVLSKLKERVIWKWEDQENTPGKSANILYSKWL 358
            :.::.: |.::.|.||.|....:|  ....:...|..:.::|.|::..:. .|....|....|||
 Frog   294 VKSSGEHGFVVFSFGSMVSEIPMN--IAMDIAEALRYIPQKVFWRYTGKA-PPNLGDNTHLVKWL 355

  Fly   359 PQDDILAHPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEE 423
            ||:|:||||..:.||.|||..|:.|...:..||:.||:..||..||..:...|.||.|::..|..
 Frog   356 PQNDLLAHPKARAFITHAGSHGVYEGICNAVPMVMLPLIGDQMDNAKRIESRGAGLILNVQNLIP 420

  Fly   424 KPFQEAILEILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVH-MSFI 487
            .....|::.::.||.|.|.::..|:|:||||:...:..::|.|:|::|.||.||: |..| :::|
 Frog   421 DDLSNAVMAVIDNPSYKENIQRLSSLHRDRPVQPLDLAVHWVEFVMKHKGAPHLR-PAAHDLNWI 484

  Fly   488 AANNIDI-CFLIFVILVSVLVLIK---FLVQFIYRRFISKPKKE 527
            ...::|: .||:.|:|.::.:.:|   |..:...:| .:|||::
 Frog   485 QYQSLDVMAFLLAVLLTTLFISLKCSTFACRCCCKR-NTKPKRK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	110/477 (23%)
ugt1a6	NP_001107366.1	UDPGT	28..527	CDD:278624	132/545 (24%)