Protein Alignment Ugt37A2 and Ugt1a6a

DIOPT Version :10

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_659545.2
• Gene: Ugt1a6a / 94284
• MGIID: 2137698
• Length: 531
• Species: Mus musculus
• Alignment Length: 541
• Identity: 152/541 - (28%)
• Similarity: 248/541 - (45%)
• Gaps: 65/541 - (12%)

  Fly    24 ANILGVFTSLSP---SHLIIQMSTAKVLAERGHNVTVITVLKPVVN-------HKNITVIMVPLT 78
            |::||....:.|   ||.:......:.|:||||:   |.||.|.||       :....:..|..:
Mouse    22 ASVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHD---IMVLVPEVNLLLGESKYYRRKIFSVTYS 83

  Fly    79 KEESQQMSDTIGAMSKTDNSNMILSMLRMMGQM----------EFMFDKMAGALKDDRVRDLYLN 133
            .||.|....|.|       :|..|....:||.:          :..|......|||...  |...
Mouse    84 LEELQTRFRTFG-------NNHFLPGASLMGPLREYRNNMIVVDMFFSNCQSLLKDSAT--LSFL 139

  Fly   134 RDNKFDLVLSGYFMNVYQLGFAKKVKAPVIVVATMPPNQLLNPLIGNPLEIAYVP----SISDSV 194
            |:||||.:.:...|....: .|:.:..|.:.:....|..|.:.|..:|..::|||    ..||.
Mouse   140 RENKFDALFTDPAMPCGVI-LAEYLNLPSVYLFRGFPCSLEHMLGQSPSPVSYVPRFYTKFSDH- 202

  Fly   195 EKGKGMSFRQRLAGYSSSFFFGIFDFVTQRRSKRLYKELFGDDPNMPEYSELVKNTSLIFFASHA 259
                 |:|.||||.:..:.......:....:.:.:..:|...|.::|.    :...||.......
Mouse   203 -----MTFPQRLANFIVNILENYLYYCLYSKYEIIASDLLKRDVSLPS----LHQNSLWLLRYDF 258

  Fly   260 PSEGPIRPNVPAAIEIGGIQVKDTPDPLPQNMAEFLGNAT--DGAILLSLGSNVKGSHINPDTVV 322
            ..|.| ||.:|..|.:|||..| ....|.|....:: ||:  .|.::.||||.|  |.|.....:
Mouse   259 VFEYP-RPVMPNMIFLGGINCK-KKGKLTQEFEAYV-NASGEHGIVVFSLGSMV--SEIPEKKAM 318

  Fly   323 KMFNVLSKLKQRVIWKWEDLEKTPGKSDNIFYSKWLPQDDILAHPNIKLFINHAGKGGITEAQYH 387
            ::...|.::.|.|:|::.. .:....:.|....|||||:|:|.||..:.||.|:|..||.|...:
Mouse   319 EIAEALGRIPQTVLWRYTG-TRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICN 382

  Fly   388 GKPMLSLPVFGDQPGNADVMVKQGFGLTQSLLSLEEQPFKEAILEILSNPQYFDKVASFSSLYRD 452
            |.||:.:|:||||..||..|..:|.|:|.::|.:.....:.|:..:::|..|.:.:...|||::|
Mouse   383 GVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKD 447

  Fly   453 RPMSARESVIYWTEYVIRHHGAAHLQSPLVH-MSFIAANNIDIYA-LIAVVLVILVLLLKLLLQF 515
            ||:...:..::|.|||:||.||.||: |..| :::...:::|:.. |:|:||.::.::.| ...:
Mouse   448 RPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFK-CCAY 510

  Fly   516 IYRKIFA------KPKKEKKH 530
            ..||.|.      |..|.|.|
Mouse   511 GCRKCFGGKGRVKKSHKSKTH 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	GT1_Gtf-like	24..464	CDD:340817	127/465 (27%)
Ugt1a6a	NP_659545.2	UDPGT	27..522	CDD:278624	145/525 (28%)