DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37A2 and ATG26

DIOPT Version :9

Sequence 1:	NP_650228.1	Gene:	Ugt37A2 / 41573	FlyBaseID:	FBgn0038082	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_013290.1	Gene:	ATG26 / 850886	SGDID:	S000004179	Length:	1198	Species:	Saccharomyces cerevisiae

Alignment Length:	471	Identity:	96/471 - (20%)
Similarity:	160/471 - (33%)	Gaps:	124/471 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 GVFTSLSPSHLIIQMSTAKVLAERGHNVTVITVLKPVVNHKNITVIMVPLTKEESQQMSDTIGAM 92
            |:.|..|...:...::..|.|.:.||.|.:||       |......:.....:..:...:.:..|
Yeast   743 GLLTIGSRGDVQPYIALGKGLIKEGHQVVIIT-------HSEFRDFVESHGIQFEEIAGNPVELM 800

  Fly    93 S-KTDNSNMILSMLRMMGQMEFMFDKMAGALKDDRVRDLYL-------NRDNKFDLVLSGYFMNV 149
            | ..:|.:|.:.|||...      .|..|.:      |..|       || .|||:::......|
Yeast   801 SLMVENESMNVKMLREAS------SKFRGWI------DALLQTSWEVCNR-RKFDILIESPSAMV 852

  Fly   150 YQLGFAKKVKAPVIVVATMP-------------PNQL----LNPLIGNPLEIAYVPSISDSVEKG 197
             .:...:.::.|.....|||             |:|.    .|.|.....|..:...||..|.|
Yeast   853 -GIHITEALQIPYFRAFTMPWTRTRAYPHAFIVPDQKRGGNYNYLTHVLFENVFWKGISGQVNK- 915

  Fly   198 KGMSFRQRLAGYSSSFFFGIFDFVTQRRSKRLYK---ELFGDDPNMPEYSELVKNTSLIFFASHA 259
                :|....|...:..|    .:.|.....||.   .:|   |...::||.|:.|...|
Yeast   916 ----WRVETLGLGKTNLF----LLQQNNVPFLYNVSPTIF---PPSIDFSEWVRVTGYWF----- 964

  Fly   260 PSEGPIRPNVPAAIEIGGIQVKDTPDPLPQNMAEFLGNATD----------GAILLSLGSNVKGS 314
                              :..|.|..| |..:.||:..|..          |:|::|....:..:
Yeast   965 ------------------LDDKSTFKP-PAELQEFISEARSKGKKLVYIGFGSIVVSNAKEMTEA 1010

  Fly   315 HINPDTVVKMFNVLSKLKQRVIWKWEDL--EKTPGKSD-----NIFYSKWLPQDDILAHPNIKLF 372
            .:.......::.:|:|       .|.:.  :|...|::     ||.....:|.|.:.  |.:...
Yeast  1011 LVEAVMEADVYCILNK-------GWSERLGDKAAKKTEVDLPRNILNIGNVPHDWLF--PQVDAA 1066

  Fly   373 INHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLTQSLLSLEEQPFKEAILEILSNP 437
            ::|.|.|....:...|.|.:..|.||||...|..:...|.|:  :|..|..|...:|:
Yeast  1067 VHHGGSGTTGASLRAGLPTVIKPFFGDQFFYAGRVEDIGVGI--ALKKLNAQTLADAL------- 1122

  Fly   438 QYFDKVASFSSLYRDR 453
                |||:.:.:.:||
Yeast  1123 ----KVATTNKIMKDR 1134

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	egt	8..490	CDD:223071	96/471 (20%)
ATG26	NP_013290.1	GRAM	194..>239	CDD:214725
		PH-GRAM1_AGT26	219..335	CDD:275402
		PH-GRAM2_AGT26	581..673	CDD:275403
		YjiC	739..1168	CDD:224732	96/471 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000