Protein Alignment Ugt37A2 and ugt1b7

DIOPT Version :10

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001166240.1
• Gene: ugt1b7 / 795261
• ZFINID: ZDB-GENE-080227-15
• Length: 542
• Species: Danio rerio
• Alignment Length: 568
• Identity: 145/568 - (25%)
• Similarity: 255/568 - (44%)
• Gaps: 93/568 - (16%)

  Fly     7 IYLLLATAICVLGGCHGANILGVFTSLSPSHLIIQM-----STAKVLAE----RGHNVTVITVLK 62
            |.|..|:|        |..:.....|.:.|.|::.|     :..|.|||    |||.|||:.
Zfish    22 IVLTFASA--------GEAVKSKEASWTGSLLVVPMDGSHWTGVKALAEEMGRRGHKVTVVI--- 75

  Fly    63 PVVNHKNITVIMVP----LTKE----ESQQMSDTIGAMSKTDNSNMILS-MLRMMGQMEFMFDKM 118
                 ..::|::.|    :|:.    ..:|..|.:.|.    |:.::.| .|.:|.::...|..|
Zfish    76 -----PEVSVLLGPGKHYVTRTFPVLYGKQQLDELQAR----NAQVMESKQLPLMEKISTRFSNM 131

  Fly   119 AGALKDDR--VRDLYLN-------RDNKFDLVLS----------GYFMNVYQLGFAKKVKAPVIV 164
            ...:...|  ...|.||       |...||.||:          .|.:::..:...:.:...:..
Zfish   132 RKFVNLQRATAESLLLNQELVDFLRKQNFDAVLTSPAVPTGAILAYNLSLPAVYMLRGLPCGLDS 196

  Fly   165 VATMPPNQLLNPLIGNPLEIAYVPS-ISDSVEKGKGMSFRQR----LAGYSSSFFFGIFDFVTQR 224
            |||..||.        |   :|:|. .:.|.::   |||.||    |..........:..:.|:.
Zfish   197 VATACPNP--------P---SYIPRFFTHSSDR---MSFGQRVLNVLVSMLEPLLCRLIYWTTED 247

  Fly   225 RSKRLYKELFGDDPNMPEYSELVKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVKDTPDPLPQ 289
            .:.|..:.    |.::   :|::.:.:|.........|.| :|.:|..:.||||... ...||.:
Zfish   248 VASRFMQR----DVSV---TEVLSSGALWLLRYDFTLEFP-KPLMPNMVLIGGINCA-IRHPLTK 303

  Fly   290 NMAEFL-GNATDGAILLSLGSNVKGSHINPDTVVKMFNVLSKLKQRVIWKW--EDLEKTPGKSDN 351
            .:.||: |:...|.::.||||.|  |.:..:.....|...|.:.|||:|::  |.....|   :|
Zfish   304 EVEEFVNGSGEHGIVVFSLGSLV--SSMPKEKADIFFKAFSMIPQRVLWRYTGEIPNNVP---EN 363

  Fly   352 IFYSKWLPQDDILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLTQ 416
            :...|||||:|:|.||..:.||.|.|..||.|...||.||:.||:||||..|...:..:|.|:..
Zfish   364 VKLMKWLPQNDLLGHPKARAFITHGGTHGIYEGICHGVPMVMLPLFGDQADNVHRVATRGVGVIL 428

  Fly   417 SLLSLEEQPFKEAILEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHHGAAHLQSPL 481
            |:..:..:...:|:..:::|..|..|:...|:::.|||:...:..::|||:|:||.||.||:...
Zfish   429 SIHDITVETLLDALNSVINNSSYKQKMQKLSAIHNDRPIQPLDLAVFWTEFVMRHKGADHLRPAA 493

  Fly   482 VHMSFIAANNIDIYALIAVVLVILVLLLKLLLQFIYRKIFAKPKKEKK 529
            ..::::..:::|:...:.::::|:.|.:.......:|:...|.:|.|:
Zfish   494 HELNWLQYHSLDVIGFMLLIVLIVTLAMLKCCSLCWRRCCRKTQKRKE 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	GT1_Gtf-like	24..464	CDD:340817	123/484 (25%)
ugt1b7	NP_001166240.1	UDPGT	42..538	CDD:278624	137/535 (26%)