Protein Alignment Ugt37A2 and UGT2B17

DIOPT Version :9

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001068.1
• Gene: UGT2B17 / 7367
• HGNCID: 12547
• Length: 530
• Species: Homo sapiens
• Alignment Length: 543
• Identity: 138/543 - (25%)
• Similarity: 251/543 - (46%)
• Gaps: 97/543 - (17%)

  Fly    36 SHLIIQMSTAKVLAERGHNVTVITVLKPVVNHKNITVIMVPLTKEESQQMSDTIGAMSKTD---- 96
            ||.|...:..:.|.:|||.|.|:|         :...|:|..:|..:.::.....:::|.|
Human    34 SHWINMKTILEELVQRGHEVIVLT---------SSASILVNASKSSAIKLEVYPTSLTKNDLEDF 89

  Fly    97 ------------NSNMILSMLRMMGQMEFMFDKMAGALKDDRVRDLYLNR---DNKFDLVLSGYF 146
                        :.|...|....:.::.:.:......|.:|.|.:..|.|   ::|||::|:.
Human    90 FMKMFDRWTYSISKNTFWSYFSQLQELCWEYSDYNIKLCEDAVLNKKLMRKLQESKFDVLLAD-- 152

  Fly   147 MNVYQLGFAKKVKAPVIVVATMPPNQLLNPLIGNPLEIAYVPSISDSVEKGKG------------ 199
                               |..|..:||..|:..|...:...|:..:|||..|
Human   153 -------------------AVNPCGELLAELLNIPFLYSLRFSVGYTVEKNGGGFLFPPSYVPVV 198

  Fly   200 -------MSFRQRLAGYSSSFFFGIFDFVTQ----RRSKRLYKELFGDDPNMPEYSELVKNTSLI 253
                   |.|.:|:   .:..:...|||..|    ::..:.|.|:.|....:   .|.:....:.
Human   199 MSELSDQMIFMERI---KNMIYMLYFDFWFQAYDLKKWDQFYSEVLGRPTTL---FETMGKAEMW 257

  Fly   254 FFASHAPSEGPIRPNVPAAIEIGGIQVKDTPDPLPQNMAEFL-GNATDGAILLSLGSNVKGSHIN 317
            ...::...|.| ||.:|....:||:..|.. .|||:.|.||: .:..:|.::.||||.:  |:::
Human   258 LIRTYWDFEFP-RPFLPNVDFVGGLHCKPA-KPLPKEMEEFVQSSGENGIVVFSLGSMI--SNMS 318

  Fly   318 PDTVVKMFNVLSKLKQRVIWKWEDLEKTPGKSDNIFYS-----KWLPQDDILAHPNIKLFINHAG 377
            .::...:.:.|:::.|:|:|:::      ||..|...|     |||||:|:|.||..|.||.|.|
Human   319 EESANMIASALAQIPQKVLWRFD------GKKPNTLGSNTRLYKWLPQNDLLGHPKTKAFITHGG 377

  Fly   378 KGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLTQSLLSLEEQPFKEAILEILSNPQYFDK 442
            ..||.||.|||.||:.:|:|.||..|...|..:|..|:..:.::..:....|:..::::|.|.:.
Human   378 TNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRTMSSRDLLNALKSVINDPIYKEN 442

  Fly   443 VASFSSLYRDRPMSARESVIYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDIYA-LIAVVLVILV 506
            :...|.::.|:|:...:..::|.|:|:||.||.||:....::::|..:::|:.| |:|.|..::.
Human   443 IMKLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWIQYHSLDVIAFLLACVATMIF 507

  Fly   507 LLLKLLLQFIYRKIFAKPKKEKK 529
            ::.|..| |.:||: ||..|:||
Human   508 MITKCCL-FCFRKL-AKTGKKKK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	egt	8..490	CDD:223071	123/501 (25%)
UGT2B17	NP_001068.1	UDPGT	24..518	CDD:278624	131/530 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150270
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840