Protein Alignment Ugt37A2 and Ugt2a3

DIOPT Version :9

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_082370.2
• Gene: Ugt2a3 / 72094
• MGIID: 1919344
• Length: 534
• Species: Mus musculus
• Alignment Length: 510
• Identity: 125/510 - (24%)
• Similarity: 244/510 - (47%)
• Gaps: 35/510 - (6%)

  Fly    36 SHLIIQMSTAKVLAERGHNVTVITVLKPVVNHKNITVIMVPLTKEESQQMSDTIGAMSKTDN--- 97
            ||.:...:..:.|..|||.|||:.....:::...    .:||..|....:.:...|.::.:.
Mouse    34 SHWLNLKTILEELGARGHEVTVLKYPSIIIDQSK----RIPLHFENIPLLYEIETAENRLNEIAN 94

  Fly    98 --SNMI--LSMLRMMGQMEFMFDKMAGALKDDRVRDLYLN-------RDNKFDLVLSGYFMNVYQ 151
              .|:|  ||:......::..|.::.|.. :...|.:..|       ||.::|:|:....:...:
Mouse    95 LAVNVIPNLSLWEAAKTLQDFFLQVTGDF-ESICRSVLYNQKFMDKLRDAQYDVVVIDPVVPCGE 158

  Fly   152 LGFAKKVKAPVIVVATMPPNQLLNPLIGN-PLEIAYVPSISDSVEKGKGMSFRQRLAGYSSSFFF 215
            | .|:.::.|.:..........:....|. |:.::|||.:..  |....|:|.:|:   .:..|.
Mouse   159 L-VAEVLQIPFVYTLRFSMGYYMEKHCGQLPIPLSYVPVVMS--ELTDNMTFTERV---KNMMFS 217

  Fly   216 GIFDFVTQRRSKRLYKELFGDDPNMP-EYSELVKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQ 279
            .:|::..|:.....:.:.:.:....| .:.:.|....:....::...|.| ||.:|....:||:.
Mouse   218 LLFEYWLQQYDFAFWDQFYSETLGRPTTFCKTVGKADIWLIRTYWDVEFP-RPYLPNFEFVGGLH 281

  Fly   280 VKDTPDPLPQNMAEFLGNATD-GAILLSLGSNVKGSHINPDTVVKMFNVLSKLKQRVIWKWEDLE 343
            .|.. .|||:.|.||:.::.: |.::.||||.||  ::..:....:.:||:::.|:|:|::...:
Mouse   282 CKPA-KPLPKEMEEFVQSSGEHGVVVFSLGSMVK--NLTEEKANLIASVLAQIPQKVLWRYSGKK 343

  Fly   344 -KTPGKSDNIFYSKWLPQDDILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVM 407
             .|.|.:..:|  .|:||:|:|.||..|.||.|.|..||.||.|||.||:.:|:.||||.|...|
Mouse   344 PATLGSNTRLF--NWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVGVPMLGDQPHNIAHM 406

  Fly   408 VKQGFGLTQSLLSLEEQPFKEAILEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHH 472
            ..:|..|..|:.::.......|:..:::.|.|.:.....|.::.|:|:...:..::|.|:|:||.
Mouse   407 EAKGAALKVSISTMTSTDLLSAVRAVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHK 471

  Fly   473 GAAHLQSPLVHMSFIAANNIDIYALIAVVLVILVLLLKLLLQFIYRKIFAKPKKE 527
            ||.||:.....:|:...:::|:...:.:.:|.|..::.....|:.:|::.|..|:
Mouse   472 GAKHLRVAAHDLSWFQYHSLDVIGFLLLCVVTLTFIITKFCLFVCQKLYMKESKK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	egt	8..490	CDD:223071	118/471 (25%)
Ugt2a3	NP_082370.2	UDPGT	25..526	CDD:278624	124/508 (24%)
		egt	<268..507	CDD:223071	77/243 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840294
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.840