Protein Alignment Ugt37A2 and Ugt2b1

DIOPT Version :9

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_690024.1
• Gene: Ugt2b1 / 71773
• MGIID: 1919023
• Length: 529
• Species: Mus musculus
• Alignment Length: 560
• Identity: 143/560 - (25%)
• Similarity: 262/560 - (46%)
• Gaps: 62/560 - (11%)

  Fly     1 MVHKSGIYLLLATAICVL--GGCHGANILGVFTSLSPSHLIIQMSTAKVLAERGHNVTVI----T 59
            |..|.....||...||.:  |.|  ..:|...|..  ||.|........|.:|||:|||:    :
Mouse     1 MSMKQASVFLLIQFICYIRPGAC--GKVLVWPTEY--SHWINMKIILDELVQRGHDVTVLISSAS 61

  Fly    60 VLKPVVNHK--NITVIMVPLTKEESQQMSDT-IG-------------AMSK-----TDNSNMILS 103
            :|....|..  |..:...||:|::.:...:. :|             :.||     ::.|:||.|
Mouse    62 ILIGPSNESSINFEIYSAPLSKDDLEYAFEKWVGNWTYELKKLPFWTSYSKLQKISSEYSDMIES 126

  Fly   104 MLRMMGQMEFMFDKMAGALKDDRVRDLYLNRDNKFDLVLSGYFMNVYQLGFAKKVKAPVIVVATM 168
            ..:.:...:.:..|:.|               :|||:||:...:...:| .::.:|.|::.....
Mouse   127 FCKAVVWNKSLMKKLQG---------------SKFDVVLADALVPCGEL-LSELLKTPLVYSLRF 175

  Fly   169 PPNQLLNPLIGN-PLEIAYVPSISDSVEKGKGMSFRQRLAGYSSSFFFGIFDFVTQRRSKRLYKE 232
            .|........|. ||..:|||.:..  |....|:|.:|:.......   :|||..|..:::.:.:
Mouse   176 CPGYKCEKYSGGLPLPPSYVPVVLS--ELSDHMTFAERVKNMLQVL---LFDFWFQTFNEKSWNQ 235

  Fly   233 LFGDDPNMP-EYSELVKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVKDTPDPLPQNMAEFLG 296
            .:.|....| ..:|::....:....:....:.| .|.:|....:||:..|.. .|||:.|.||:.
Mouse   236 FYSDVLGRPTTLTEMMGKADIWLVRTFWDLKFP-HPFLPNFDFVGGLHCKPA-KPLPKEMEEFVQ 298

  Fly   297 NATD-GAILLSLGSNVKGSHINPDTVVKMFNVLSKLKQRVIWKWEDLE-KTPGKSDNIFYSKWLP 359
            ::.: |.::.||||.||  :|..:....:.:.|:::.|:|:|:::..: .|.|.:..::  ||:|
Mouse   299 SSGEHGVVVFSLGSMVK--NIKEEKANVVASALAQIPQKVLWRFDGKKPDTLGSNTRLY--KWIP 359

  Fly   360 QDDILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLTQSLLSLEEQ 424
            |:|:|.||..|.||.|.|..||.||.|||.|::.:|:|||||.|.:.:|.:|..:.....::...
Mouse   360 QNDLLGHPKTKAFIAHGGTNGIYEAIYHGIPIVGIPLFGDQPDNINHIVAKGAAVRVDFDTMSTT 424

  Fly   425 PFKEAILEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHHGAAHLQSPLVHMSFIAA 489
            ....|:..::::|.|.:.....|.::.|:||...:..::|.|||:|:.||.||:..|..:::...
Mouse   425 DLLTALKTVINDPSYKENAMRLSRIHHDQPMKPLDRAVFWIEYVMRNKGAKHLRPALHDLTWFQY 489

  Fly   490 NNIDIYALIAVVLVILVLLLKLLLQFIYRKIFAKPKKEKK 529
            :::|:...:.|.:|.:|.::.....|...|.....||:|:
Mouse   490 HSLDVIGFLLVCVVAVVFIIAKCCLFCCHKTANMGKKKKE 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	egt	8..490	CDD:223071	132/512 (26%)
Ugt2b1	NP_690024.1	egt	8..508	CDD:223071	136/530 (26%)
		UDPGT	24..527	CDD:278624	133/531 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840525
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.840