Protein Alignment Ugt37A2 and Ugt1a3

DIOPT Version :10

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_958827.1
• Gene: Ugt1a3 / 396551
• RGDID: 1549728
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 554
• Identity: 149/554 - (26%)
• Similarity: 254/554 - (45%)
• Gaps: 61/554 - (11%)

  Fly     5 SGIYLLLATAICVLGGCHGANILGVFTSLSPSHLIIQMSTAKVLAERGHNVTV----ITVLKPVV 65
            ||:.|||    |.|....|..:| || .:..||.:......:.|..|||...|    :||.....
  Rat    11 SGLLLLL----CALPWAEGGKVL-VF-PMEGSHWLSMRDVVRELHARGHQAVVLAPEVTVHIKEE 69

  Fly    66 NHKNITVIMVPLTKEESQQMSDTIGAMS---KTDNS-NMILSMLRMMGQMEFMFDKMAGALKDDR 126
            :...:....||.||||.:.  ..:|.:.   :|:.| .::|..:..:..:...:.:....|..:.
  Rat    70 DFFTLQTYPVPYTKEEYRH--HLLGHLQNFFETEFSLKLVLQRMAAVNNVSTFYVRSCRGLLHNT 132

  Fly   127 VRDLYLNRDNKFDLVLSGYFMNVYQLG--FAKKVKAPVIVVATMPPNQLLNPLIGNPLEIAYVPS 189
            .....|| .:.||:||:..|   :..|  .|..::.|.:........:|......:|...:|:|.
  Rat   133 ALIQSLN-SSSFDVVLTDPF---FPCGAVLAMYLRVPAVFFLQSMLCELEFEATNSPNPSSYIPR 193

  Fly   190 I----SDSVEKGKGMSFRQRLAGYSSSFFFGIFDFVTQRRSKRLYKELFGDDPNMPEYSELVKNT 250
            :    ||.      |||..|:........:.....|......||..:|...:.::   .|::::.
  Rat   194 LLTLNSDH------MSFLDRVKNMLYPVPWMYLCHVNYGSLARLASDLLQREVSV---VEILRHA 249

  Fly   251 SLIF----FASHAPSEGPIRPNVPAAIEIGGIQVKDTPDPLPQNMAEFLGNAT--DGAILLSLGS 309
            |:..    |..:.|     ||.:|..:.||||...:. .||.|....:: ||:  .|.::.||||
  Rat   250 SVWLLRKDFVFYYP-----RPFMPNMVFIGGINCANR-KPLSQEFEAYV-NASGEHGIVVFSLGS 307

  Fly   310 NVKGSHINPDTVVKMFNVLSKLKQRVIWKWEDLEKTPGKSDNIFYSKWLPQDDILAHPNIKLFIN 374
            .|  |.|.....:::...|.::.|.|:|::.. .:....:.|....|||||:|:|.||..:.||.
  Rat   308 MV--SEIPEKKAMEIAEALGRIPQTVLWRYTG-TRPSNLAKNTILVKWLPQNDLLGHPKARAFIT 369

  Fly   375 HAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLTQSLLSLEEQPFKEAILEILSNPQY 439
            |:|..||.|...:|.||:.:|:||||..||..|..:|.|:|.::|.:.....:.|:..:::|..|
  Rat   370 HSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSY 434

  Fly   440 FDKVASFSSLYRDRPMSARESVIYWTEYVIRHHGAAHLQSPLVH-MSFIAANNIDIYA-LIAVVL 502
            .:.:...|||::|||:...:..::|.|||:||.||.||: |..| :::...:::|:.. |:|:||
  Rat   435 KENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAIVL 498

  Fly   503 VILVLLLKLLLQFIYRKIFA------KPKKEKKH 530
            .::.::.| ...:..||.|.      |..|.|.|
  Rat   499 TVVFIVYK-SCAYGCRKCFGGKGRVKKSHKSKTH 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	GT1_Gtf-like	24..464	CDD:340817	116/459 (25%)
Ugt1a3	NP_958827.1	UDPGT	26..522	CDD:278624	137/524 (26%)