Protein Alignment Ugt37A2 and Ugt1a6b

DIOPT Version :9

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_958812.3
• Gene: Ugt1a6b / 394435
• MGIID: 3580629
• Length: 531
• Species: Mus musculus
• Alignment Length: 541
• Identity: 154/541 - (28%)
• Similarity: 248/541 - (45%)
• Gaps: 65/541 - (12%)

  Fly    24 ANILGVFTSLSP---SHLIIQMSTAKVLAERGHNVTVITVLKPVVN-------HKNITVIMVPLT 78
            |::||....:.|   ||.:......:.|:||||:   |.||.|.||       :....:..||.:
Mouse    22 ASVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHD---IVVLVPEVNLLLGESKYYRRKIFSVPYS 83

  Fly    79 KEESQQMSDTIGAMSKTDNSNMILSMLRMMG----------QMEFMFDKMAGALKDDRVRDLYLN 133
            .||.|....|.|       .|..:....:||          .:|..|......|||...  |...
Mouse    84 LEELQTRFRTFG-------RNQFVPGAPLMGPLREYRNSMLTLEMFFSNCQSLLKDSAT--LSFL 139

  Fly   134 RDNKFDLVLSGYFMNVYQLGFAKKVKAPVIVVATMPPNQLLNPLIGNPLEIAYVP----SISDSV 194
            |:||||.:.:...|....: .|:.:..|.:.:....|..|.:.|..:|..::|||    ..||.
Mouse   140 RENKFDALFTDPAMPCGVI-LAEYLNLPSVYLFRGFPCSLEHMLGQSPSPVSYVPRFYTKFSDH- 202

  Fly   195 EKGKGMSFRQRLAGYSSSFFFGIFDFVTQRRSKRLYKELFGDDPNMPEYSELVKNTSLIFFASHA 259
                 |:|.||||.:..:.......:....:.:.:..:|...|.::|.    :...||.......
Mouse   203 -----MTFPQRLANFIVNILENYLYYCLYSKYEIIVTDLLKRDVSLPS----LHQNSLWLLRYDF 258

  Fly   260 PSEGPIRPNVPAAIEIGGIQVKDTPDPLPQNMAEFLGNAT--DGAILLSLGSNVKGSHINPDTVV 322
            ..|.| ||.:|..|.||||..| ....|.|....:: ||:  .|.::.||||.|  |.|.....:
Mouse   259 VFEYP-RPIMPNMIFIGGINCK-KKGKLTQEFEAYV-NASGEHGIVVFSLGSMV--SEIPEKKAM 318

  Fly   323 KMFNVLSKLKQRVIWKWEDLEKTPGKSDNIFYSKWLPQDDILAHPNIKLFINHAGKGGITEAQYH 387
            ::...|.::.|.|:|::.. .:....:.|....|||||:|:|.||..:.||.|:|..||.|...:
Mouse   319 EIAEALGRIPQTVLWRYTG-TRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICN 382

  Fly   388 GKPMLSLPVFGDQPGNADVMVKQGFGLTQSLLSLEEQPFKEAILEILSNPQYFDKVASFSSLYRD 452
            |.||:.:|:||||..||..|..:|.|:|.::|.:.....:.|:..:::|..|.:.:...|||::|
Mouse   383 GVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKD 447

  Fly   453 RPMSARESVIYWTEYVIRHHGAAHLQSPLVH-MSFIAANNIDIYA-LIAVVLVILVLLLKLLLQF 515
            ||:...:..::|.|||:||.||.||: |..| :::...:::|:.. |:|:||.::.::.| ...:
Mouse   448 RPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFK-CCAY 510

  Fly   516 IYRKIFA------KPKKEKKH 530
            ..||.|.      |..|.|.|
Mouse   511 GCRKCFGGKGRVKKSHKSKTH 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	egt	8..490	CDD:223071	141/492 (29%)
Ugt1a6b	NP_958812.3	egt	15..503	CDD:223071	146/510 (29%)
		UDPGT	27..522	CDD:278624	147/525 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840717
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840