Protein Alignment Ugt37A2 and Ugt1a9

DIOPT Version :10

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_964006.2
• Gene: Ugt1a9 / 394434
• MGIID: 3576092
• Length: 528
• Species: Mus musculus
• Alignment Length: 567
• Identity: 144/567 - (25%)
• Similarity: 238/567 - (41%)
• Gaps: 97/567 - (17%)

  Fly     9 LLLATAICVLGGCHGANILGVFTSLSPSHLIIQMSTAKVLAERGHNVTVITVLKPVVNHKNITVI 73
            ||||:.:...|     .:|.|  .:..||........:.|..|||.|                |:
Mouse    14 LLLASGLAQAG-----RLLVV--PMDGSHWFTMQMVVEKLIHRGHEV----------------VV 55

  Fly    74 MVPLTKEESQQMSDTIGAMSKT----------DNSNMILSMLR---------------MMGQMEF 113
            ::|   |.|.|:..::....||          |.....||..:               ..|..|.
Mouse    56 VIP---EVSWQLGKSLNCTVKTYSISHTLEDLDREFKYLSYTQWKTPEHSIRSFLTGSARGFFEL 117

  Fly   114 MFDKMAGALKDDRVRDLYLNRDNKFDLVLSGYFMNVYQLGFAKKVKAPVIVVATMPPNQLLNPLI 178
            .|........|.::.: || :...||.|....| :|..|..||....|.::.|.......|....
Mouse   118 TFSHCRSLFNDKKLVE-YL-KQRFFDAVFLDPF-DVCGLIVAKYFSLPSVIFARGVFCDYLEEGA 179

  Fly   179 GNPLEIAYVPSI----SDSVEKGKGMSFRQRLAGY--------SSSFFFGIFDFVTQRRSKRLYK 231
            ..|...:|||.:    :|:      |:|::|:..:        ..|:|.        |.:..:..
Mouse   180 QCPSLPSYVPRLFSKYTDT------MTFKERVWNHLIYIEEHAFCSYFL--------RTAVEVAS 230

  Fly   232 ELFGDDPNMPEYSELVKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVKDTPDPLPQNMAEFLG 296
            |:......|   ::|....|:....:....|.| ||.:|..:.||||..........:..|....
Mouse   231 EILQTPVTM---TDLFSPVSIWLLRTDFVLEFP-RPVMPNMVFIGGINCLQKKSLSKEFEAYVNA 291

  Fly   297 NATDGAILLSLGSNVKGSHINPDTVVKMFNVLSKLKQRVIWKWEDLEKTPGKSDNIFYSKWLPQD 361
            :...|.::.||||.|  |.|.....:::...|.::.|.|:|::.. .:....:.|....|||||:
Mouse   292 SGEHGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTG-TRPSNLAKNTILVKWLPQN 353

  Fly   362 DILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLTQSLLSLEEQPF 426
            |:|.||..:.||.|:|..||.|...:|.||:.:|:||||..||..|..:|.|:|.::|.:.....
Mouse   354 DLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDL 418

  Fly   427 KEAILEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHHGAAHLQSPLVH-MSFIAAN 490
            :.|:..:::|..|.:.:...|||::|||:...:..::|.|||:||.||.||: |..| :::...:
Mouse   419 ENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYH 482

  Fly   491 NIDIYA-LIAVVLVILVLLLKLLLQFIYRKIFA------KPKKEKKH 530
            ::|:.. |:|:||.::.::.| ...:..||.|.      |..|.|.|
Mouse   483 SLDVIGFLLAIVLTVVFIVFK-CCAYGCRKCFGGKGRVKKSHKSKTH 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	GT1_Gtf-like	24..464	CDD:340817	114/476 (24%)
Ugt1a9	NP_964006.2	UDPGT	24..519	CDD:278624	136/546 (25%)