Protein Alignment Ugt37A2 and Ugt2b37

DIOPT Version :10

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001007265.4
• Gene: Ugt2b37 / 29623
• RGDID: 3937
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 553
• Identity: 151/553 - (27%)
• Similarity: 259/553 - (46%)
• Gaps: 64/553 - (11%)

  Fly     9 LLLATAICVLGGCHGANILGVFTSLSPSHLIIQMSTAKVLAERGHNVTVITVLKP----VVNHK- 68
            |||..:.|:.....|..::   ..:..||.:...:....|.:|||.|   |||||    |::.|
  Rat    10 LLLQISFCLRSAKCGKVLV---WPMEFSHWMNIKTILDELVQRGHEV---TVLKPSAYYVLDPKK 68

  Fly    69 ----NITVIMVPLTKEESQQ-MSDTIGAMSKTDNSNMILSMLRMMGQMEFMFDKMAGALKDDRVR 128
                ........::|:|.:: ....:.|.:.....:..||...::..|.            |...
  Rat    69 SPDLKFETFPTSVSKDELEKYFIKLVDAWTYELQRDTCLSFSPLLQNMM------------DEFS 121

  Fly   129 DLYLN---------------RDNKFDLVLSGYFMNVYQLGFAKKVKAPVIVVATMPPNQLLNPLI 178
            |.||:               :::|||::||.......:| .|:.:..|.:......|...:....
  Rat   122 DYYLSVCKDAVSNKQLMAKLQESKFDVLLSDPVAACGEL-IAEVLHIPFLYSLRASPGHKIEKSS 185

  Fly   179 GN-PLEIAYVPSISDSVEKGKGMSFRQRLAGYSSSFFFGI-FDFVTQRRSKRLYKELFGDDPNMP 241
            |. .|..:|||.|...:  |..|:|..|:.......:|.. |.....:.....|.|:.|....:
  Rat   186 GRFILPPSYVPVILSGL--GGQMTFIDRVKNMICMLYFDFWFHMFNAKNWDPFYTEILGRPTTL- 247

  Fly   242 EYSELVKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVKDTPDPLPQNMAEFLGNATD-GAILL 305
              :|.:....:....|:...|.| .|.:|....|||:|.|.. .|||:::.:|:.::.: |.::.
  Rat   248 --AETMGKAEMWLIRSYWDLEFP-HPTLPNVDYIGGLQCKPA-KPLPKDIEDFVQSSGEHGVVVF 308

  Fly   306 SLGSNVKGSHINPDTVVKMFNVLSKLKQRVIWKWE-DLEKTPGKSDNIFYSKWLPQDDILAHPNI 369
            ||||.|  |.:..:....:...|:::.|:|:||:: .:..|.|.:..::  |||||:|:|.||..
  Rat   309 SLGSMV--SSMTEEKANAVAWALAQIPQKVLWKFDGKIPATLGPNTRVY--KWLPQNDLLGHPKT 369

  Fly   370 KLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLTQSLLSLEEQPFKEAILEIL 434
            |.|:.|.|..|:.||.|||.||:.:|:||:|..|...||.:|..:|.::.::.:.....|:.|::
  Rat   370 KAFVTHGGANGVYEAIYHGIPMIGIPMFGEQHDNIAHMVAKGAAVTLNIRTMSKSDLFNALKEVI 434

  Fly   435 SNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHHGAAHLQSPLVH-MSFIAANNIDIYA-L 497
            :||.|.......|:::.|:||...:..|:|.|||:||..|.||: ||.| :.:...:::|:.. |
  Rat   435 NNPFYKKNAMWLSTIHHDQPMKPLDKAIFWIEYVMRHKRAKHLR-PLGHNLPWYQYHSLDVIGFL 498

  Fly   498 IAVVLVILVLLLKLLLQFIYRKIFAKPKKEKKH 530
            :|.:.||..|.:|..| |||| .|||.:|:.|:
  Rat   499 LACLAVIAALAVKCFL-FIYR-FFAKKQKKMKN 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	GT1_Gtf-like	24..464	CDD:340817	117/468 (25%)
Ugt2b37	NP_001007265.4	UDPGT	24..527	CDD:278624	146/535 (27%)