Protein Alignment Ugt37A2 and Ugt2b7

DIOPT Version :10

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_775445.2
• Gene: Ugt2b7 / 286989
• RGDID: 708417
• Length: 529
• Species: Rattus norvegicus
• Alignment Length: 573
• Identity: 149/573 - (26%)
• Similarity: 258/573 - (45%)
• Gaps: 106/573 - (18%)

  Fly     9 LLLATAICVLGGCHGANILGVFTSLSPSHLIIQMSTAKVLAERGHNVTVITVLKPVVNHKNITVI 73
            |||..:.|...|..|..::   ..|..||.:........|.:|||.|   |||:|     :.:|.
  Rat    10 LLLQISFCFRSGNCGKVLV---WPLEYSHWMNLKIILDELVQRGHEV---TVLRP-----SSSVF 63

  Fly    74 MVPLTKEESQQMSDTIGAMSKTDNSNMILSM--------------LRMMGQMEFMFDKMAGALKD 124
            :.|  |:.|..:.:|....|..|......:.              ||....:..||.:.:
  Rat    64 LDP--KKASGLVYETFPTTSNNDEVEKFFTQWVNTWTYDVPKYTCLRYYPSLNKMFGQFS----- 121

  Fly   125 DRVRDLYLN---------------RDNKFDLVLS------GYFMN-------VYQLGFA-----K 156
                ||:|.               ::::||:|||      |..:.       ||.|.|.     :
  Rat   122 ----DLWLQLCREVVSNKHLMAKLKESQFDVVLSDAVGPCGELIAEILQLPFVYSLRFGIGYGIE 182

  Fly   157 KVKAPVIVVATMPPNQLLNPLIGNPLEIAYVPSISDSVEKGKGMSFRQRLAGYSSSFFFGI-FDF 220
            |..|                  |.|...:|||.|...: .|: |:|.:|:.......:|.. |:.
  Rat   183 KYSA------------------GQPFPPSYVPIILSGL-SGQ-MTFMERVENMLCLLYFDFWFES 227

  Fly   221 VTQRRSKRLYKELFGDDPNMPEYSELVKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVKDTPD 285
            ...:.....:.|:.|....|   .:.:|...:....|:...|.| ||::|....:||:..:.. .
  Rat   228 FPAKDWDPFFSEILGRPTTM---VDTMKKAEIWLIRSYWDLEFP-RPSLPNIEFVGGLHCQPA-K 287

  Fly   286 PLPQNMAEFLGNATD-GAILLSLGSNVKGSHINPDTVVKMFNVLSKLKQRVIWKWEDLE-KTPGK 348
            |||:.|.:|..::.: |.::.||||.::  :|..:....:.:.|:::.|:|.|::|..: .|.|.
  Rat   288 PLPKEMEDFAQSSGEHGVVVFSLGSMIR--NITQERANTIASALAQIPQKVFWRFEGKKPDTLGP 350

  Fly   349 SDNIFYSKWLPQDDILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFG 413
            :..:|  ||:||:|:|.||..|.|:.|.|..||.|:.:||.||:.:|:|.:|..|...||.:|..
  Rat   351 NTRVF--KWIPQNDLLGHPKTKAFVTHGGANGIYESIHHGIPMVGIPLFAEQRDNVAHMVAKGAA 413

  Fly   414 LTQSLLSLEEQPFKEAILEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHHGAAHLQ 478
            ::....::.......|:..:::.|.|..||...|:::.|:|:...:..::|.|:|:||.||.||:
  Rat   414 VSLDFHTMSSSDLLNALKAVINKPSYKKKVMWLSAIHHDQPLKPLDRAVFWIEFVMRHKGAKHLR 478

  Fly   479 SPLVH-MSFIAANNIDIYA-LIAVVLVILVLLLKLLLQFIYRKIFAKPKKEKK 529
             ||.| :::...:::|:.. |:|.||.|::|.:|..| |:|| .|.|..|.|:
  Rat   479 -PLAHNLAWYQYHSLDVIGFLLACVLAIVLLAVKCCL-FLYR-FFVKVAKNKR 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	GT1_Gtf-like	24..464	CDD:340817	115/489 (24%)
Ugt2b7	NP_775445.2	UDPGT	24..527	CDD:278624	143/556 (26%)