Protein Alignment Ugt37A2 and Ugt2b15

DIOPT Version :10

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_695226.3
• Gene: Ugt2b15 / 266685
• RGDID: 628623
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 551
• Identity: 155/551 - (28%)
• Similarity: 267/551 - (48%)
• Gaps: 60/551 - (10%)

  Fly     9 LLLATAICVLGGCHGANILGVFTSLSPSHLIIQMSTAKVLAERGHNVTVITVLKPVVNHKNITVI 73
            |||..:.|...|..|..::   ..:..||.:...:....|.:|||.|   |||||...:     :
  Rat    10 LLLQISCCFQSGNCGKVLV---WPMEFSHWMNIKTILDELVQRGHEV---TVLKPSAYY-----V 63

  Fly    74 MVPLTKEESQQMSDTI-GAMSKTDNSNMILSMLRMMGQMEFMFD---KMAGALKD--DRVRDLYL 132
            :.|  |:......:|. .::||.:..|..:.::.:. ..|...|   ..:..|::  |...|.||
  Rat    64 LDP--KKSPDLKFETFPTSVSKDELENYFIKLVDVW-TYELQRDTCLSYSPLLQNMIDGFSDYYL 125

  Fly   133 N---------------RDNKFDLVLSGYFMNVYQLGFAKKVKAPVIVVATMPPNQLLNPLIGN-P 181
            :               :::|||::||.......:| .|:.:..|.:......|...:....|. .
  Rat   126 SLCKDTVSNKQLMAKLQESKFDVLLSDPVAACGEL-IAEVLHIPFLYSLRFSPGYKIEKSSGRFI 189

  Fly   182 LEIAYVPSISDSVEKGKGMSFRQRLAGYSSSFFFGI-FDFVTQRRSKRLYKELFGDDPNMPEYSE 245
            |..:|||.|...:  |..|:|..|:.....:.:|.. |.....::....|.|:.|....:   :|
  Rat   190 LPPSYVPVILSGM--GGPMTFIDRVKNMICTLYFDFWFHMFNAKKWDPFYSEILGRPTTL---AE 249

  Fly   246 LVKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVKDTPDPLPQNMAEFLGNATD-GAILLSLGS 309
            .:....:....|:...|.| .|.:|....|||:|.: .|.|||::|.:|:.::.: |.::.||||
  Rat   250 TMGKAEMWLIRSYWDLEFP-HPTLPNVDYIGGLQCR-PPKPLPKDMEDFVQSSGEHGVVVFSLGS 312

  Fly   310 NVKGSHINPDTVVKMFNVLSKLKQRVIWKWEDLEKTP---GKSDNIFYSKWLPQDDILAHPNIKL 371
            .|  |.:..:....:...|:::.|:|:||::.  |||   |.:..::  |||||:|:|.||..|.
  Rat   313 MV--SSMTEEKANAIAWALAQIPQKVLWKFDG--KTPATLGPNTRVY--KWLPQNDLLGHPKTKA 371

  Fly   372 FINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLTQSLLSLEEQPFKEAILEILSN 436
            |:.|.|..|:.||.|||.||:.:|:||:|..|...||.:|..:|.::.::.:.....|:.||::|
  Rat   372 FVTHGGANGVYEAIYHGIPMVGIPMFGEQHDNIAHMVAKGAAVTLNIRTMSKSDLFNALKEIINN 436

  Fly   437 PQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHHGAAHLQSPLVH-MSFIAANNIDIYA-LIA 499
            |.|.......|:::.|:||...:..::|.|:|:||.||.||: ||.| :.:...:::|:.. |:.
  Rat   437 PFYKKNAVWLSTIHHDQPMKPLDKAVFWIEFVMRHKGAKHLR-PLGHNLPWYQYHSLDVIGFLLT 500

  Fly   500 VVLVILVLLLKLLLQFIYRKIFAKPKKEKKH 530
            ...||.||.:|..| |||| :|.|.:|:.|:
  Rat   501 CSAVIAVLTVKSFL-FIYR-LFVKKEKKMKN 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	GT1_Gtf-like	24..464	CDD:340817	121/466 (26%)
Ugt2b15	NP_695226.3	UDPGT	24..527	CDD:278624	149/533 (28%)