Protein Alignment Ugt37A2 and Ugt2b35

DIOPT Version :10

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_766469.1
• Gene: Ugt2b35 / 243085
• MGIID: 3576100
• Length: 529
• Species: Mus musculus
• Alignment Length: 509
• Identity: 135/509 - (26%)
• Similarity: 240/509 - (47%)
• Gaps: 55/509 - (10%)

  Fly    48 LAERGHNVTVITVLKPVVNHKNITVIMVPLTKEESQQMSDTIGAMSKTDNSNMILSMLRMMGQME 112
            |.:|||.|   |||:|     :.::.:.|  |.......:|.......|.....|:  :::.:..
Mouse    46 LVQRGHEV---TVLRP-----SASIFVDP--KYSPGLKFETFPTAFSKDYLETFLT--KLVDEWT 98

  Fly   113 F-----------MFDKMAGALKD-------DRVRDLYLN---RDNKFDLVLSGYFMNVYQLGFAK 156
            |           :...:.|.|.|       :.|.:..|.   :::|||:::.....:..:| .|:
Mouse    99 FEVPRDTCLSYSLLQTLFGKLSDYSLSLCKEAVSNKQLMTKFQESKFDVLILDAMASCGEL-IAQ 162

  Fly   157 KVKAPVIVVATMPPN-QLLNPLIGNPLEIAYVPSISDSVEKGKGMSFRQRLAGYSSSFFFGI-FD 219
            .::.|.:......|. |:.....|..|..:|||.|...:  |..|:|.:|:.......:|.. |.
Mouse   163 LLQIPFLYSLRFSPGYQVEKNSGGFVLPPSYVPVILSGL--GGQMTFTERVKNMICMLYFDFWFQ 225

  Fly   220 FVTQRRSKRLYKELFGDDPNMPEYSELVKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVKDTP 284
            ..|::...:.|.|..|....:   .|.:....:.|..|:...|.| .|.:|....:||:..|..
Mouse   226 TFTEKEWDQFYSETLGRPTTL---IETMGKAEMWFIRSYWDLEFP-HPTLPNVEYVGGLHCKPA- 285

  Fly   285 DPLPQNMAEFL-GNATDGAILLSLGSNVKGSHINPDTVVKMFNVLSKLKQRVIWKWEDLEKTP-- 346
            .|||:.|.:|: .:...|.::.||||.|  |::..:....:...|:::.|:|:|:::.  |||
Mouse   286 KPLPKEMEDFVQSSGVHGVVVFSLGSMV--SNMTEERANAISWALAQIPQKVLWRFDG--KTPAS 346

  Fly   347 -GKSDNIFYSKWLPQDDILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQ 410
             |.:..|:  |||||:|:|.||..|.|:.|.|..|:.||.:||.||:.:|:|.:|..|...||.:
Mouse   347 LGPNTRIY--KWLPQNDLLGHPKTKAFVTHGGANGLYEAIHHGIPMIGIPLFSEQHDNIAHMVAK 409

  Fly   411 GFGLTQSLLSLEEQPFKEAILEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHHGAA 475
            |..:..::.::.......|:.|:::||.|.:.|...|:::.|:||......|:|.|:|:||.||.
Mouse   410 GTAVALNIRTMSRSDLLNALEEVINNPSYKENVMWLSTIHHDQPMKPLNRTIFWIEFVMRHKGAK 474

  Fly   476 HLQSPLVH-MSFIAANNIDIYALIAVVLVILVLLLKLLLQFIYRKIFAKPKKEK 528
            ||: ||.| :::...:::|:...:.|.:|...:|......|:|:....|.||.|
Mouse   475 HLR-PLAHNLTWYQYHSLDVIGFLLVCVVATAVLPVKCCLFVYQFFVKKAKKRK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	GT1_Gtf-like	24..464	CDD:340817	113/442 (26%)
Ugt2b35	NP_766469.1	UDPGT	24..525	CDD:278624	132/505 (26%)