Protein Alignment Ugt37A2 and Ugt2b5

DIOPT Version :10

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_033493.3
• Gene: Ugt2b5 / 22238
• MGIID: 98900
• Length: 530
• Species: Mus musculus
• Alignment Length: 513
• Identity: 144/513 - (28%)
• Similarity: 245/513 - (47%)
• Gaps: 62/513 - (12%)

  Fly    48 LAERGHNVTVIT-----VLKPVVNHKNITVIMVPLTKEESQQMSDTIGAMSKTDNSNMIL----- 102
            |.:|||.|||:.     ||.|..:         |..|.|:...|     :||.:..|..:
Mouse    46 LVQRGHEVTVLRPSAYYVLDPKKS---------PGLKFETFPTS-----VSKDNLENFFIKFVDV 96

  Fly   103 --------SMLRMMGQMEFMFDKMAG---ALKDDRVRDLYLN---RDNKFDLVLSGYFMNVYQLG 153
                    :.|.....::.|.|:.:.   :|..|.|.:..|.   :::|||::||....:..:|
Mouse    97 WTYEMPRDTCLSYSPLLQNMIDEFSDYFLSLCKDVVSNKELMTKLQESKFDVLLSDPVASCGEL- 160

  Fly   154 FAKKVKAPVIVVATMPPNQLLNPLIGN-PLEIAYVPSISDSVEKGKGMSFRQRLAGYSSSFFFGI 217
            .|:.::.|.:......|...:....|. .|..:|||.|...:  |..|:|.:|:.......:|..
Mouse   161 IAELLQIPFLYSIRFSPGYQIEKSSGRFLLPPSYVPVILSGL--GGQMTFIERIKNMICMLYFDF 223

  Fly   218 -FDFVTQRRSKRLYKELFGDDPNMPEYSELVKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVK 281
             |.....::....|.|..|....:   .|.:....:....|:...|.| .|.:|....:||:..|
Mouse   224 WFQMFNDKKWDSFYSEYLGRPTTL---VETMGQAEMWLIRSNWDLEFP-HPTLPNVDYVGGLHCK 284

  Fly   282 DTPDPLPQNMAEFLGNATD-GAILLSLGSNVKGSHINPDTVVKMFNVLSKLKQRVIWKWEDLEKT 345
            .. .|||::|.||:.::.| |.::.||||.|  |::..:....:...|:::.|:|:||::.  ||
Mouse   285 PA-KPLPKDMEEFVQSSGDHGVVVFSLGSMV--SNMTEEKANAIAWALAQIPQKVLWKFDG--KT 344

  Fly   346 P---GKSDNIFYSKWLPQDDILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVM 407
            |   |.:..::  |||||:|:|.||..|.|:.|.|..|:.||.|||.||:.:|:||:|..|...|
Mouse   345 PATLGHNTRVY--KWLPQNDLLGHPKTKAFVTHGGANGVYEAIYHGIPMIGIPLFGEQHDNIAHM 407

  Fly   408 VKQGFGLTQSLLSLEEQPFKEAILEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHH 472
            |.:|..:..::.::.:.....|:.|::.||.|.......|:::.|:||...:..::|.|:|:||.
Mouse   408 VAKGAAVALNIRTMSKSDVLNALEEVIENPFYKKNAMWLSTIHHDQPMKPLDRAVFWIEFVMRHK 472

  Fly   473 GAAHLQSPLVH-MSFIAANNIDIYA-LIAVVLVILVLLLKLLLQFIYRKIFAKPKKEK 528
            .|.||: ||.| :::...:::|:.. |::.|...:||.:|.|| ||||....|..|.|
Mouse   473 RAKHLR-PLGHNLTWYQYHSLDVIGFLLSCVATTIVLSVKCLL-FIYRFFVKKENKMK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	GT1_Gtf-like	24..464	CDD:340817	118/445 (27%)
Ugt2b5	NP_033493.3	UDPGT	24..527	CDD:278624	142/510 (28%)