Protein Alignment Ugt37A2 and ugt-57

DIOPT Version :10

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_509182.1
• Gene: ugt-57 / 180969
• WormBaseID: WBGene00017154
• Length: 558
• Species: Caenorhabditis elegans
• Alignment Length: 602
• Identity: 133/602 - (22%)
• Similarity: 236/602 - (39%)
• Gaps: 151/602 - (25%)

  Fly    26 ILG---VFTSLSPSHLIIQMST-----------AKVLAERGHNVTVI---------TVLKPVVNH 67
            :||   :.|||  :.|:..:.|           |:.||.|.|||..|         .::||.::.
 Worm     7 LLGLTQIVTSL--NILVFLLGTNQFERNIFEFLAQQLALRHHNVISIKPVLIPEEPRLVKPKLHL 69

  Fly    68 KNITVIMVPLTKEESQQMSDTI-----------------------GAMSKTDNSNMILSMLRMMG 109
            ....||...|.|:..:.:.|.:                       .:..|..|||::.|:.:...
 Worm    70 VREKVIKNVLNKDLFKPLEDAVPNAAWRSTYDFDNYLEPYYKAHNASCYKLLNSNLVDSLKKESL 134

  Fly   110 QMEFMF--DKMAGALKD-DRVRDLYLNRDNKFD--LVLSGYFMNVYQLGFAKKVKAPVIVVATMP 169
            .:..::  :....||.. ..|..:|.:.:...|  |:.:|               ||:.:: |.|
 Worm   135 DLAIVYSGNPCLNALTHLVAVPTIYFDTEGLTDETLIAAG---------------APIDLL-TPP 183

  Fly   170 PNQLLNPLIGNPL------EIAY---------VPSISDSVEKGKGMSFRQRLAGYSSSFFFGIFD 219
            .:..:....|.|:      .:.|         :|::|..|      |.|.||.....:..|.. |
 Worm   184 SHCFIAESKGYPILNLYKNSVCYFQEMIAQLGLPAVSSLV------SSRHRLLDEPITNIFRT-D 241

  Fly   220 FVTQRRSKRLYKELFGDDPNMPEYSELVKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVKDTP 284
            :..::|.|           |.|..:.| |..|..:|.:..|...|.|......|.:||:.: |.|
 Worm   242 YTIKKRFK-----------NFPNVNTL-KQQSAAYFVNTDPLLEPPRALPLNVIPVGGLHI-DHP 293

  Fly   285 DPL--PQNMAEFLGNATDGAILLSLGSNVKGSHINPDTVVKMFNVLSKLKQ-RVIWK-------- 338
            .||  |.|..  :.:|.:|.|::|.|:....|.::......:...|:.|.. |:.|:
 Worm   294 KPLFSPWNTT--IASAKEGLIIVSFGTQADSSKMSEYHAKAILKALTNLNDYRIYWRIGPNMHLD 356

  Fly   339 WEDLEKTPGKSDNIFYSKWLPQDDILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGN 403
            ..|:||.|   .:|..:.::||:|:|||.:.|||:.:.|...:.||..||.|::.:|::|....|
 Worm   357 GIDIEKIP---KHINLTTFIPQNDLLAHKSCKLFVTNGGMSSVMEAVAHGVPIVGVPLYGSNRYN 418

  Fly   404 ADVMVKQGFGLTQSLLSLEEQPFKEAILEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYV 468
            ...:..:|.|:......|.|.....|:.::|.:.:|.:.....|..::.|..|...:.::..:::
 Worm   419 LQKVSNKGLGIVIDKDDLNEISLYGAMKKVLESAKYKNTAKEMSKEFKSRTTSPFAAALHVIDHI 483

  Fly   469 IRHHGAAHLQ---SPLVHMSFIAANNIDIYALIAVVLVILVLLLKLLLQFIY------------- 517
            .|||..|::|   .|:.       ..:|.|.|:   |:||:.::.|.|.|.:
 Worm   484 GRHHSFAYMQPAFQPIY-------TRVDFYLLL---LIILLPVIPLHLFFTFCIKSSAMNVQDNK 538

  Fly   518 -----RKIFAKPKKEKK 529
                 ||...|...|.|
 Worm   539 VLEAERKFLPKKVPETK 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	GT1_Gtf-like	24..464	CDD:340817	113/514 (22%)
ugt-57	NP_509182.1	GT1_Gtf-like	<168..477	CDD:340817	81/349 (23%)