Protein Alignment Ugt37A2 and ugt-11

DIOPT Version :10

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_504311.1
• Gene: ugt-11 / 178882
• WormBaseID: WBGene00020593
• Length: 533
• Species: Caenorhabditis elegans
• Alignment Length: 572
• Identity: 137/572 - (23%)
• Similarity: 240/572 - (41%)
• Gaps: 97/572 - (16%)

  Fly     9 LLLATAICVLGGCHGANILGVFTSL-SPSHLIIQMSTAKVLAERGHNVTV-------ITVLKPVV 65
            ||..:.:|.|...:.|..:.:|..: ..||:......|.::|:.|..||:       :..|..:|
 Worm     3 LLTFSCLCFLLKVNYAAKILIFNPIFGFSHVKFVSKLADIIADHGQEVTLFQPFHLALKNLDGIV 67

  Fly    66 NHKNITVIMV------PLTKEESQQMSDTIGAMSKTDNSNMILSMLRMMGQMEFMFDKMAGA--- 121
            .:|||.:|..      .|.|.|:|...|...:...   :|.:|        |.||..::.|.
 Worm    68 KNKNIEIINYYPDHYDDLLKLETQTFPDFWDSQLM---NNPVL--------MAFMLPRILGGEFK 121

  Fly   122 ------LKDDRVRDLYLNRDNKFDLVLS------GYFMNVYQLGFAKKVKAPVIVVATMPPNQLL 174
                  :||..:  |...:|.|||:.:|      |.:|:.: ||      .|.|.:.:.....:.
 Worm   122 KTTIQLIKDKEI--LKKLKDKKFDVAISETFELTGMYMSHF-LG------VPCIPILSAVRLDIF 177

  Fly   175 NPLIGNPLEIAYVPSISDSVEKGKGMSFRQRLAGYSSSFFFGIFDFVTQRRSKRLYKEL--FGDD 237
            |...|......|:......:....|  |..||......||           ||..::.:  :.:|
 Worm   178 NEAFGQSSAFGYLTQQGSKLAPDAG--FLDRLNDVYRDFF-----------SKMAFRGMAQYQND 229

  Fly   238 -------PNMPEYSELVKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVK----DTPDPLPQNM 291
                   ..:|.:.:|||... ::..:..|......|.....:.||||.:.    :..|.||:..
 Worm   230 VIEKAAGHVVPYWKDLVKEAP-VYMTNSNPYLDFAVPTTATIVHIGGITINLEKMNHVDALPEEY 293

  Fly   292 AEFLGNATDGAILLSLGSNVKGSHINPDT----VVKMFNVLSKLKQRVIWKWE--DLEKTPGKSD 350
             |.:....:..:|:|.||.:: |:..|:.    ::|:|..|..:  ..|||:|  |||.......
 Worm   294 -EIILKEKETTVLISFGSVIR-SYEMPENFKAGLIKVFESLPDV--IFIWKYEIDDLEFQKKLPK 354

  Fly   351 NIFYSKWLPQDDILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLT 415
            |:...||:||..:||...:|||:.|.|.|...|..|.|||.|.:|:|||||.|||::.:.|..:.
 Worm   355 NVHLKKWVPQPSLLADKRVKLFVTHGGLGSTMEVAYTGKPALMVPIFGDQPMNADMLARHGGAIA 419

  Fly   416 QSLLSL-EEQPFKEAILEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHHGAAHLQS 479
            .....| :.:...|.:.::::||:|..|......:..::|:....:::...|:.|:.   .:|:|
 Worm   420 YDKFDLVDGKKLTETVRDLVTNPKYEQKAKELLDVLTNQPIDPVMNLMKHLEFAIKF---PNLRS 481

  Fly   480 PLVHMSFIAANNIDIYALIAVVLVILVLLLKLLLQF-----IYRKIFAKPKK 526
            .:..::.:..  |..|.|..:|.:|.|.::...:.|     |..:|.:|..|
 Worm   482 QIPEINQVGP--IAHYYLDVIVFLIFVSIITAYISFQIVCRILSRILSKKVK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	GT1_Gtf-like	24..464	CDD:340817	118/488 (24%)
ugt-11	NP_504311.1	GT1_Gtf-like	19..452	CDD:340817	116/470 (25%)