Protein Alignment Ugt37A2 and ugt-45

DIOPT Version :10

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_500410.2
• Gene: ugt-45 / 177139
• WormBaseID: WBGene00021372
• Length: 527
• Species: Caenorhabditis elegans
• Alignment Length: 559
• Identity: 134/559 - (23%)
• Similarity: 231/559 - (41%)
• Gaps: 75/559 - (13%)

  Fly     7 IYLLLATAICVLGGCHGANILGVFTSLSPSHLIIQMSTAKVLAERGHNVTV---ITVLKPVVNHK 68
            ::|||  .:.....|:  .||........||:......|.:|.|.||:||.   :.|..|....:
 Worm     5 VFLLL--FVLPAASCY--KILVSVPKFGFSHMQTMGKLADILVEAGHDVTFLMPVDVPIPQNGTE 65

  Fly    69 NITVIMVPLTKEESQQMSDTI--GAMSK--TDNSNM---ILSMLRMMGQMEFMFDKMAGALKDDR 126
            ...|::||.|...::.|...:  ||::.  |.::|.   |:....|:||:.:...|   .|.|::
 Worm    66 LAKVVLVPTTDAINEIMGHAMKSGAVANLWTHSANSKQGIMWSTDMIGQVSYHNTK---NLIDNK 127

  Fly   127 --VRDLYLNRDNKFDLVLSGYFMNVYQLGFAKKVKAPVIVVA---TMPPNQLLNPLIGNPLEIAY 186
              |:.:   :|.|||:.::..| :...|.|.:.:....::.|   ::....|:  ..|.|:..::
 Worm   128 ALVQQM---KDEKFDIGITELF-DFSGLAFFEVIGLKNVMGAHTTSVFEGTLM--ATGAPILPSF 186

  Fly   187 VPSISDSVEKGKGMSFRQRLAGYSSSFFFGIFDFVTQRRSKRLYKELFGDDPNMPEYSELVKNTS 251
            ||: |.:.....| |...||.....:::...|....|..:::...|.: :....|:...||.:.:
 Worm   187 VPA-SQTFTDDSG-SILSRLNNLYMTYWSYQFQNKIQSFAQKALDEHY-EKGKAPKIWNLVSDIT 248

  Fly   252 LIFFASHAPSEGPIRPNVPAAIEIGGIQVKDTPDPLPQNMAEFLGNATD---------GAILLSL 307
            . ||.:..|                   :.|.|.|||||:.|..|.:..         ..||...
 Worm   249 W-FFVNSDP-------------------IFDFPKPLPQNIVEIAGISVPEIKPVGKEWDEILSKR 293

  Fly   308 GSNVK---GSHINPDT--------VVKMFNVLSKLKQRVIWKWEDLE-KTPGKSDNIFYSKWLPQ 360
            ..||.   ||..:|.|        :|..|.....:  ..|||::|.| |.....||:...||:||
 Worm   294 SKNVLVSFGSIASPTTMPEAVKKSIVDAFAAFPDV--TFIWKYDDTESKLTAHLDNVHIVKWMPQ 356

  Fly   361 DDILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLTQSLLSLEE-Q 424
            :|:||...|.:|..|.|.|.:.|:.....|::.:|:||||..||.:..:.|..|....:.|.. :
 Worm   357 NDLLADKRISMFWTHGGMGSLMESAQKSVPLVVVPIFGDQMRNAQIAKRHGVALIYDKMDLSNTK 421

  Fly   425 PFKEAILEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHHGAAHLQSPLVHMSFIAA 489
            ....|:.|:|.||:|.......:.:......|.|:.:|...|...|........|.....||:..
 Worm   422 KLIGALKEVLENPEYKKSAELLARILATERFSPRQKIIDTVEMAGRFGQMPRWTSAGKEFSFLKY 486

  Fly   490 NNIDIYALIAVVLVILVLLLKLLLQFIYRKIFAKPKKEK 528
            .|:|:..:...:..:.::...||::.:..|:.....|||
 Worm   487 FNLDLVIIAVFIFFLSIVSTVLLIRHLLAKLGFSGDKEK 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	GT1_Gtf-like	24..464	CDD:340817	117/476 (25%)
ugt-45	NP_500410.2	GT1_Gtf-like	18..448	CDD:340817	114/465 (25%)