Protein Alignment Ugt37A2 and UGT3A2

DIOPT Version :9

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: XP_011512290.1
• Gene: UGT3A2 / 167127
• HGNCID: 27266
• Length: 550
• Species: Homo sapiens
• Alignment Length: 576
• Identity: 145/576 - (25%)
• Similarity: 246/576 - (42%)
• Gaps: 121/576 - (21%)

  Fly    24 ANILGVFTSLSPSHLIIQMSTAKVLAERGHNVTVITVLKPVVNHKN-----------ITVIMVP- 76
            |.||.:.| :..||.::....:::|.:.|||||::       |||.           .:....|
Human    23 AKILTIST-VGGSHYLLMDRVSQILQDHGHNVTML-------NHKRGPFMPGLSDSPASASRYPR 79

  Fly    77 ---------------------------LTKEESQQ---------MSDTIGAMSKTDNSNMILSML 105
                                       |..|:.|:         :.:|:|...|.:|
Human    80 ILYLQKYCQFGLKDFKKEEKSYQVISWLAPEDHQREFKKSFDFFLEETLGGRGKFEN-------- 136

  Fly   106 RMMGQMEFMFDKMAGALKDDRVRDLYLNRDNKFDLVLSGYFMNVYQLGFAKKVKAPVIVVATMPP 170
             ::..:|::..:.:..|....:.|...|.:  ||:|:...| :......|:|:..|.:.:.:...
Human   137 -LLNVLEYLALQCSHFLNRKDIMDSLKNEN--FDMVIVETF-DYCPFLIAEKLGKPFVAILSTSF 197

  Fly   171 NQLLNPLIGNPLEIAYVPSISDSVEKGKGMSFRQRLAGYSSSF-----FFGIFDFVTQRRSKRL- 229
            ..|   ..|.|:.::|||            .||..|..:...:     |...|.|.  ||.:.:
Human   198 GSL---EFGLPIPLSYVP------------VFRSLLTDHMDFWGRVKNFLMFFSFC--RRQQHMQ 245

  Fly   230 ------YKELFGDDPNMPEYSELVKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVKDTPDPLP 288
                  .||.| .:.:.|..|.|:....|.|..|....:. .||.:|..:.:||:..|.. .|:|
Human   246 STFDNTIKEHF-TEGSRPVLSHLLLKAELWFINSDFAFDF-ARPLLPNTVYVGGLMEKPI-KPVP 307

  Fly   289 QNMAEFLGNATD-GAILLSLGSNVKGSHINPDTVVKMFNVLSKLKQRVIWK-----WEDLEKTPG 347
            |::..|:....| |.:|::|||.|.... ||:...:|.|..:.|.|.||||     |   .|...
Human   308 QDLENFIAKFGDSGFVLVTLGSMVNTCQ-NPEIFKEMNNAFAHLPQGVIWKCQCSHW---PKDVH 368

  Fly   348 KSDNIFYSKWLPQDDILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGF 412
            .:.|:....||||.|:||||:|:||:.|.|:..|.||..||.||:.:|:|||||.|...:..:.|
Human   369 LAANVKIVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVEAKKF 433

  Fly   413 GLTQSLLSLEEQPFKEAILEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHHGAAHL 477
            |::..|..|:.:.....:.:|:.:.:|.....:.|.:.|..|:|..:.::.|.::|::..||.||
Human   434 GVSIQLKKLKAETLALKMKQIMEDKRYKSAAVAASVILRSHPLSPTQRLVGWIDHVLQTGGATHL 498

  Fly   478 QSPLV-----HMSFIAANNIDIYA-LIAVVLVILVLLLKLLLQFIYRKIFAKPKKE 527
            : |.|     |..::    :|::. |:.:.|..|.|..|||...::....|:..||
Human   499 K-PYVFQQPWHEQYL----LDVFVFLLGLTLGTLWLCGKLLGMAVWWLRGARKVKE 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	egt	8..490	CDD:223071	134/536 (25%)
UGT3A2	XP_011512290.1	UDPGT	23..518	CDD:278624	135/543 (25%)
		egt	<162..517	CDD:223071	109/386 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150564
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840