Protein Alignment Ugt37A2 and Ugt2b34

DIOPT Version :10

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_705826.1
• Gene: Ugt2b34 / 100727
• MGIID: 2140962
• Length: 532
• Species: Mus musculus
• Alignment Length: 538
• Identity: 134/538 - (24%)
• Similarity: 255/538 - (47%)
• Gaps: 66/538 - (12%)

  Fly    38 LIIQMS-------TAKVLA---ERGHNVTVITVLKPVVNHKNITVIMVPLTKEESQQMSDTIGAM 92
            |::|:|       ..|||.   |..|.:.:.|:|..::...:..:::.| :...|.::.:|....
Mouse    12 LLLQLSGFFGSGTGGKVLVWPMEFSHWLNLKTILDELLKKGHEVMVLRP-SASLSYEVDNTSAIE 75

  Fly    93 SKTDNSNMILSMLR------------------------MMGQMEFMFDKMAGALKDDRVRDLYLN 133
            .:|..::..||.|.                        |:.:|.::..|...:|    .:|:..|
Mouse    76 FETYPTSYSLSELEEIFWESLKKYIYELPKQSFWGYFLMLQEMVWVDSKYFESL----CKDVVFN 136

  Fly   134 RD-------NKFDLVLSGYFMNVYQLGFAKKVKAPVIVVATMPPNQLLNPLIGN-PLEIAYVPSI 190
            ::       ::||::|:..|:....| .|:.:|.|::......|........|. ||..:|||.:
Mouse   137 KELMTKLQKSRFDVILADPFIPCGDL-LAEVLKIPLVYSLRFFPGSTYEKYSGGLPLPPSYVPVV 200

  Fly   191 SDSVEKGKGMSFRQRLAG--YSSSFFFGIFDFVTQRRSKRLYKELFGDDPNMPEYSELVKNTSLI 253
            ..  |....|:|.:|:..  |...|.|. |....::...:||.|:.|....:   ||.:....:.
Mouse   201 MS--ELSDRMTFMERVRNVIYMLCFDFW-FQTFNEKNWNQLYTEVLGRPTTL---SETMAKADIW 259

  Fly   254 FFASHAPSEGPIRPNVPAAIEIGGIQVKDTPDPLPQNMAEFLGNATD-GAILLSLGSNVKGSHIN 317
            ...::...|.| .|.:|....|||:..:.. .|||:.:.:|:.::.: |.::.||||.| || |.
Mouse   260 LIRTYWDLEFP-HPVLPNFDFIGGLHCRPA-KPLPKEIEDFVQSSGEHGVVVFSLGSMV-GS-IT 320

  Fly   318 PDTVVKMFNVLSKLKQRVIWKWEDLE-KTPGKSDNIFYSKWLPQDDILAHPNIKLFINHAGKGGI 381
            .:....:...|:::.|:|:|::|..: :|.|.:..::  ||:||:|:|.|...:.||.|.|..||
Mouse   321 EERANVIAAGLAQIPQKVLWRFEGKKPETLGSNTRLY--KWIPQNDLLGHSKTRAFITHGGTNGI 383

  Fly   382 TEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLTQSLLSLEEQPFKEAILEILSNPQYFDKVASF 446
            .||.|||.|::.:|:||||..|...:..:|..:....|::.......|:..:.::|.|.:.....
Mouse   384 YEAIYHGIPVVGIPLFGDQYDNIVHLKAKGAAVRLDFLTMSSTDLHTALKTVTNDPSYKENAMRL 448

  Fly   447 SSLYRDRPMSARESVIYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDIYA-LIAVVLVILVLLLK 510
            |.::.|:|:...:..::|.|:|:||.||.||:.....:|::..:::|:.. |:|.||.::.:|.|
Mouse   449 SRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWVQYHSLDVLGFLLACVLTVMFILKK 513

  Fly   511 LLLQFIYRKIFAKPKKEK 528
            ..| |..:|:....:|:|
Mouse   514 CCL-FCCQKLTKAGRKKK 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	GT1_Gtf-like	24..464	CDD:340817	112/471 (24%)
Ugt2b34	NP_705826.1	UDPGT	27..529	CDD:278624	129/520 (25%)