Protein Alignment Ugt37A2 and ugt1b3

DIOPT Version :9

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001170817.1
• Gene: ugt1b3 / 100384903
• ZFINID: ZDB-GENE-080227-12
• Length: 535
• Species: Danio rerio
• Alignment Length: 579
• Identity: 140/579 - (24%)
• Similarity: 261/579 - (45%)
• Gaps: 100/579 - (17%)

  Fly     2 VHKSGIYLLLATAICVLGGCHGANI---LGVFTSLSPSHLIIQM---------STAKVLAERGHN 54
            :|...|:.|:...:|      .|.:   |...:|.:...|::.|         :.|:.:..|||
Zfish     5 MHLGVIFCLVVGVVC------SAAVDQKLSRKSSWTGKLLVVPMDGSHWTGVKAVAEEMGRRGH- 62

  Fly    55 VTVITVLKPVVNH----KNITVIMVPLTKEE---SQQMSDTIGAMSKTDNSNMILSMLRMMGQME 112
             |||.|:..:...    |:......|:..::   ::.:::.:..::...:|. :.::...|..:.
Zfish    63 -TVIVVIPEISMRLGPGKHYITKKFPVKYDQKLFNEVLTEHVHEVTNPGHSR-LKTVTSTMANLL 125

  Fly   113 FMFDKMAG---ALKDDRVRDLYLNRDNKFDLVLS----------GYFMNVYQLGFAKKVKAPVIV 164
            .||:.||.   :|..|:....:| ||..||.:|:          .|..:|..:...:.:...:..
Zfish   126 KMFNMMASTSESLFQDKELIKFL-RDENFDAILTDPALPMGAVLAYNFSVPAVYMLRGMPCALDA 189

  Fly   165 VATMPPNQLLNPLIGNPLEIAYVPSI-SDSVEKGKGMSFRQRLAGYSSSF--------FFGIFDF 220
            .||..||        .|   :|:|.. :.:.::   |||.:|:.....|.        .:..|:.
Zfish   190 TATACPN--------TP---SYIPRFHTGNTDR---MSFGERVMNVLMSILEQVACKVMYWSFEE 240

  Fly   221 VTQRRSKRLYKELFGDDPNMPEYSELVKNTSLIF-----FASHAPSEGPIRPNVPAAIEIGGIQ- 279
            ||....:|        |.::.|    :.:|..::     |....|.  |:.||:..   ||||.
Zfish   241 VTPNFLQR--------DVSLTE----ILSTGAVWLMRYDFTLEFPK--PLMPNMQF---IGGINC 288

  Fly   280 -VKDTPDPLPQNMAEFL-GNATDGAILLSLGSNVKGSHINPDTVVKMFNVLSKLKQRVIWKW--E 340
             ||   :||.:.:.||: |:...|.::.||||.|  |.:..:.....|...|.:.|||:|::  |
Zfish   289 GVK---NPLMKEVEEFVNGSGEHGIVVFSLGSLV--SSMPKEKADIFFKAFSMIPQRVLWRYTGE 348

  Fly   341 DLEKTPGKSDNIFYSKWLPQDDILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNAD 405
            .....|   :|:...|||||:|:|..|..:.||.|.|..||.|...||.||:.||:||||..|..
Zfish   349 IPNNVP---ENVKLMKWLPQNDLLGPPKARAFITHGGTHGIYEGICHGVPMVMLPLFGDQADNVH 410

  Fly   406 VMVKQGFGLTQSLLSLEEQPFKEAILEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIR 470
            .:..:|.|:..|:..:..:...:|:..:::|..|..|:...|:::.|||:...:..::|||:|:|
Zfish   411 RVATRGVGVILSIHDITVETLLDALNSVINNSSYKQKMQKLSAIHNDRPIQPLDLAVFWTEFVMR 475

  Fly   471 HHGAAHLQSPLVHMSFIAANNIDIYALIAVVLVILVLLLKLLLQFIYRKIFAKPKKEKK 529
            |.||.||:.....::::..:::|:...:.::::|:.|.:.......:|....|.:|.|:
Zfish   476 HKGADHLRPAAHELNWLQYHSLDVIGFMLLIVLIVTLAMLKCCSLCWRCCCRKTQKRKE 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	egt	8..490	CDD:223071	131/532 (25%)
ugt1b3	NP_001170817.1	UDPGT	35..516	CDD:278624	129/523 (25%)
		egt	<275..514	CDD:223071	80/249 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584787
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930