Protein Alignment Ugt37A2 and ugt1a4

DIOPT Version :10

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001170815.3
• Gene: ugt1a4 / 100384901
• ZFINID: ZDB-GENE-080227-3
• Length: 520
• Species: Danio rerio
• Alignment Length: 555
• Identity: 143/555 - (25%)
• Similarity: 250/555 - (45%)
• Gaps: 73/555 - (13%)

  Fly     9 LLLATAICVLGGCHGANILGVFTSLSPSHLIIQMSTAKVLAERGHNVTVI--------------T 59
            |.|...:.:.|......:| |..| ..||.:......:.|..||:.|.|:              |
Zfish     4 LWLLVGLFLFGSAEAGKLL-VIPS-DGSHWLGMKPVVEELGRRGNQVVVVIPEASLSMGPSEKTT 66

  Fly    60 VLKPVVNHKNITVIMV---PLTKEESQQMSDTIGAMSKTDNSNMILSMLRMMGQMEFMFDKMAGA 121
            .|...||:....:.||   .||:..|...|        |:.|...:..|::.....|:.....|.
Zfish    67 TLTYPVNYTKAELHMVLEGNLTEILSTDFS--------TELSKFFVFFLQLKVLQNFIVRNAEGL 123

  Fly   122 L-KDDRVRDLYLNRDNKFDLVLSGYFMNVYQLGFAKKVKAPVIVVATMPPNQLLNPLIGNPLEIA 185
            | .:|.::.|   :|.|||.:|:..|..|..:. ::.:..|.|.:....|..:.:.....|...:
Zfish   124 LFNEDLMKKL---QDCKFDAILTDPFEPVGVIA-SEYLSIPAIYMQVNLPCGVDSLASQCPSPPS 184

  Fly   186 YVPS----ISDSVEKGKGMSFRQR--------LAGYSSSFFFGIFDFVTQRRSKRLYKELFGDDP 238
            |||.    .:|.      |:..||        |...:..:.:...|.:..|..:|
Zfish   185 YVPQRNTHFTDQ------MNIWQRCINLVRTLLQHMACRYMYAEADEIASRFLQR---------- 233

  Fly   239 NMPEYSELVKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVKDTPDPLPQNMAEFL-GNATDGA 302
             .....|::...:|.........|.| ||.:|..:.|||:..| .|.||.:.:.||: |:...|.
Zfish   234 -RASIVEIMNRATLWLMRFDFAFEFP-RPLMPNMVMIGGMATK-KPKPLSKELEEFVNGSGEHGF 295

  Fly   303 ILLSLGSNVKGSHINPDTVVKMFNVLSKLKQRVIWKWED--LEKTPGKSDNIFYSKWLPQDDILA 365
            ::.:|||.|  |.:......:.|....::.|||:|::..  .|..|   .|:...|||||:|:|.
Zfish   296 VVFTLGSMV--SQLPEAKAREFFEAFRQIPQRVLWRYTGPVPENAP---KNVKLMKWLPQNDLLG 355

  Fly   366 HPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLTQSLLSLEEQPFKEAI 430
            ||.::.|:.|.|..||.|...:|.||:.||:||||..||..:|.:|...:.::..:..:....|:
Zfish   356 HPKVRAFVTHGGSHGIYEGICNGVPMVMLPLFGDQGDNAQRLVSRGVAESLTIYDVTSEKLLVAL 420

  Fly   431 LEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHHGAAHLQSPLVH-MSFIAANNIDI 494
            .:::::..|.:|:...|:::||||:...:..::|||:|:||.||.||: |..| :::|..:::|:
Zfish   421 KKVINDKSYKEKMMKLSAIHRDRPIEPLDLAVFWTEFVMRHKGAEHLR-PAAHDLNWIQYHSLDV 484

  Fly   495 YALIAVVLVILVLLLKLLLQFIYRKIFAKPKKEKK 529
            ...:.::|:.::.:......|.:||.|.|.:|:||
Zfish   485 IGFLLLILLTVIFVTVKSCMFCFRKCFKKSQKKKK 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	GT1_Gtf-like	24..464	CDD:340817	117/472 (25%)
ugt1a4	NP_001170815.3	None