Protein Alignment Ugt37A2 and ugt1a6

DIOPT Version :10

• Sequence 1: NP_650228.1
• Gene: Ugt37A2 / 41573
• FlyBaseID: FBgn0038082
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001107366.1
• Gene: ugt1a6 / 100135191
• XenbaseID: XB-GENE-5793241
• Length: 531
• Species: Xenopus tropicalis
• Alignment Length: 563
• Identity: 151/563 - (26%)
• Similarity: 249/563 - (44%)
• Gaps: 91/563 - (16%)

  Fly     8 YLLLATAICVLGGCHGANILGVFTSLSPSHLIIQMSTAKVLAERGHNVTVI-----TVLKPVVNH 67
            ::|||     ||...|..:|.|  ....||.:........||:|||.:.|.     .:.|.:.|:
 Frog    17 FILLA-----LGCADGGRLLVV--PQDGSHWLSMRVLVDRLAQRGHYIVVAIPEVNMLFKDLDNY 74

  Fly    68 KNITVIMVPLTKEESQQMSDTIGAMSKTDNSNMILSMLRMMGQMEFMFDKMAGALK--------- 123
            | :.....|.:|       |.:....:..|..:.:..: :..::.|.::.|:.|.:
 Frog    75 K-VKTFSSPYSK-------DVLENRMRRMNQEIFVDRI-LTEKITFWYESMSNATQWVVSACQHF 130

  Fly   124 ---DDRVRDLYLNRDNKFDLVLSGYFMNVYQLG--FAKKVKAPVIVVATMPPNQLLNPLIG---- 179
               ...:|:|   ....||.:|:.   :|:..|  .|:.:..|.:       :.:...:.|
 Frog   131 LQNSTLIREL---EKEHFDAMLTD---SVFPCGEIVAEHLSIPSV-------SFMRGTIFGMDQI 182

  Fly   180 ---NPLEIAYVPSI----SDSVEKGKGMSFRQRLAGY----SSSFFFGIFDF-VTQRRSKRLYKE 232
               .|...:|||.:    :|:      |||.||:..:    .......||.: ..|..|..|.||
 Frog   183 ASQTPSPPSYVPRMFTVYTDN------MSFSQRVKNFLIHSLEHIVCHIFYYPYAQMASDFLKKE 241

  Fly   233 LFGDDPNMPEYSELVKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVKDTPDPLPQNMAEFLGN 297
            :..        ..|...||:.........|.| ||.:|..|.||||... ....|||...:.:.:
 Frog   242 VTA--------MSLFSRTSIWLMRYDFVFEFP-RPIMPNVILIGGINCA-KQKALPQEFEKLVKS 296

  Fly   298 ATD-GAILLSLGSNVKGSHINPDTVVKMFNVLSKLKQRVIWKWEDLEKTPGKSDNIFYSKWLPQD 361
            :.: |.::.|.||.|  |.|..:..:.:...|..:.|:|.|::.. :..|...||....|||||:
 Frog   297 SGEHGFVVFSFGSMV--SEIPMNIAMDIAEALRYIPQKVFWRYTG-KAPPNLGDNTHLVKWLPQN 358

  Fly   362 DILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLTQSLLSLEEQPF 426
            |:||||..:.||.|||..|:.|...:..||:.||:.|||..||..:..:|.||..::.:|.....
 Frog   359 DLLAHPKARAFITHAGSHGVYEGICNAVPMVMLPLIGDQMDNAKRIESRGAGLILNVQNLIPDDL 423

  Fly   427 KEAILEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHHGAAHLQSPLVH-MSFIAAN 490
            ..|::.::.||.|.:.:...|||:||||:...:..::|.|:|::|.||.||: |..| :::|...
 Frog   424 SNAVMAVIDNPSYKENIQRLSSLHRDRPVQPLDLAVHWVEFVMKHKGAPHLR-PAAHDLNWIQYQ 487

  Fly   491 NIDIYA-LIAVVLVILVLLLKLLLQFIYR---KIFAKPKKEKK 529
            ::|:.| |:||:|..|.:.|| ...|..|   |...|||::.|
 Frog   488 SLDVMAFLLAVLLTTLFISLK-CSTFACRCCCKRNTKPKRKTK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A2	NP_650228.1	GT1_Gtf-like	24..464	CDD:340817	118/475 (25%)
ugt1a6	NP_001107366.1	UDPGT	28..527	CDD:278624	144/543 (27%)