|
Fly 10 GNSTLMALEKGMQADDKENAQPGNGNIQVQSAGNEVNSEIQEINSEFFRDEFSYEVNQAHKPAEQ 74
|:|....|..|: .:||||....|...|:......|| ::.|........|........|...
Frog 17 GSSLSKILFGGL--TNKENAGNRKGTPTVRGVLGPHNS--RKRNRPTSSSPGSESSTSPSSPKRA 77
Fly 75 SVVNVSQVQQHMAVVSNQDSEDQSRSSALNDQICTQSSFEGEDAGADAVLDQPNLDENSFLCPAQ 139
:|...::.:.|.:..|.:....:|.|..| |:......|..|.:|..|.
Frog 78 TVGRQNRPRPHTSRASQRRRRSESGSDTL------QNGSVAPSAHRDFILFSPT----------- 125
Fly 140 DEEASEQLKEDILHSHSVLAKQEFYQ-EISQVTQNLSSMSP--NQLRVSPNSSRIREAM------ 195
|..|:|.||:..: :.|:...::|.::| ...|...:|||:.|::
Frog 126 -------------HQASILGKQKGQEPQRSRANLSVSVLTPPAGLERSLIDSSRLNESVCGSGQG 177
Fly 196 PERPAMPLDLNTLRSISAWNLPMSIQAEYKKKGVVDMFDWQVECLSKPRLLFEHCNLVYSAPTSA 260
|.. |:|..|.....:::|.||.::..:|...||..||:||.|||...::| |..||||||||||
Frog 178 PHM-AVPDALADKLMLASWGLPKTVLEKYGSLGVSQMFEWQAECLMLGQVL-EGKNLVYSAPTSA 240
Fly 261 GKTLVSEILMLKTVLERGKKVLLILPFISVVREKMFYMQDLLTPAGYRVEGFYGGYTPPGGFESL 325
|||||:|:|:||.|||..:|.|.||||:||.:||.||:|:|....|.:|:|:.|..:|.|||.||
Frog 241 GKTLVAELLILKRVLETRRKALFILPFVSVAKEKTFYLQNLFQEVGVKVDGYMGSSSPAGGFCSL 305
Fly 326 HVAICTIEKANSIVNKLMEQGKLETIGMVVVDEVHLISDKGRGYILELLLAKILYMSRRNGL--- 387
.||:|||||||.:||:|:|:.|::.:||:||||:|::.|..|||:|||||.|:.|::::..:
Frog 306 DVAVCTIEKANGLVNRLIEENKIDLLGMMVVDELHMLGDSHRGYLLELLLTKVRYVTQKGAVGRK 370
Fly 388 --------QIQVITMSATLENVQLLQSWLDAELYITNYRPVALKEMIKVGTVIYDHRLKLVRDVA 444
.:|::.|||||.|:.||.:|||||||.|::|||.|.|.:|:|..:||..:..||:..
Frog 371 AEGAGPANDVQIVGMSATLPNLGLLAAWLDAELYHTDFRPVPLLERVKIGRTVYDSNMVAVREFE 435
Fly 445 KQKVLLKGLENDSDDVALLCIETLLEGCSVIVFCPSKDWCENLAVQLATAIHVQIKSETVLGQRL 509
. |..::.|.|.:..|..||:..|.|:::|||||:|||.||..:|...:
Frog 436 P----LLPVKGDDDHIVSLSYETVRGGHSILIFCPSKNWCEKLADTIAREFY------------- 483
Fly 510 RTNLNPRA----------------------IAEVKQQLRDIPTGLDGVMSKAITYACAFHHAGLT 552
||..|| |.:|..||:..|.|||.|:.:.:.:..||||||||
Frog 484 --NLFHRAQQRGDAGGSDSFVPPVALDRDGIRDVMDQLKRSPAGLDAVLGRTVPWGVAFHHAGLT 546
Fly 553 TEERDIIEASFKAGALKVLVATSTLSSGVNLPARRVLIRSPLFGGKQMSSLTYRQMIGRAGRMGK 617
.:||||:|.:|:.|.::||.||||||||||||||||:||||||.|:.:..|||:||.|||||.|.
Frog 547 FDERDIVEGAFRQGFVRVLAATSTLSSGVNLPARRVIIRSPLFNGRLLDILTYKQMAGRAGRKGV 611
Fly 618 DTLGESILICNEINARMGRDLVVSELQPITSCL------DMDGSTHLKRALLEVISSGVANTKED 676
||.|||||:|.......|..|:...|:|:.||| .:.|| :.||:||:|..|||:|.||
Frog 612 DTEGESILVCKNPERAKGISLLQGSLKPVQSCLLRKEGAGVTGS--MIRAILEIIVGGVADTPED 674
Fly 677 IDFFVNCTLLSAQKAFHAKEKPPDEESDANYINDALDFLVEYEFVRLQRNEERET--AVYVATRL 739
:..:.:||||:|.......:: :||.....|...:|:|:..||:::...:...| .||..|:|
Frog 675 VRIYASCTLLAASMKQGGGDQ--EEEHGGGAIEACVDWLLRNEFIQILEEDRGGTKAEVYRPTKL 737
Fly 740 GAACLASSMPPTDGLILFAELQKSRRSFVLESELHAVYLVTPYSVCYQLQDIDWLLYVHMWEKLS 804
|||.|:||:.|::.|.:||:||::.:.||||::||.:||||| |..:...|||..:..:||||.
Frog 738 GAATLSSSLSPSEALGIFADLQRAMKGFVLENDLHILYLVTP--VYEEWTTIDWYQFFCLWEKLP 800
Fly 805 SPMKKVGELVGVRDAFLYKALRGQ--TKLD--YKQMQIHKRFYIALALEELVNETPINVVVHKYK 865
:.||:|.||||:.:.||.:::.|: .|.| ::|:.||:||:.:|.|.:|::|..:..:..||.
Frog 801 TSMKRVAELVGIEEGFLARSVNGKIVAKNDRQHRQIAIHRRFFTSLVLLDLISEVSLKELTKKYG 865
Fly 866 CHRGMLQSLQQMASTFAGIVTAFCNSLQWSTLALIVSQFKDRLFFGIHRDLIDLMRIPDLSQKRA 930
|.||.||||||.|:|:||:||.|.|.|.|..:.|::|||:.||.||:.|:|.||:|:..|:.:||
Frog 866 CSRGQLQSLQQSAATYAGMVTVFSNRLGWHNMELLLSQFQSRLTFGVQRELCDLVRVDLLNAQRA 930
Fly 931 RALFDAGITSLVELAGADPVELEKVLYNSISFDSAKQHDHENADEAAKRNVVRNFYITGKAGMTV 995
|||::||:.::.|||.|..:::|..|.|::.|.|.:|...|..:.|.:|...|..:|.|:.|:|.
Frog 931 RALYNAGLVTVAELARAHVIDVETALKNAVPFKSGRQAVDEEEEAAEERRAARCIWIPGRKGLTE 995
Fly 996 SEAAKLLIGEARQFVQHEIGLGTIKW-------TQTQAGVEIASRAIHDGGEVDLHMS------- 1046
.|||:|::||||:.::|::.|..|:| :.:.:|...|:.:.|...::.|..|
Frog 996 REAAELIVGEARRLLKHDLALIGIEWNPESSLESSSDSGRGSANGSAHGPAQLALISSGESARVV 1060
Fly 1047 ------------------------------------------------LEEEQPPVKRKLSIEEN 1063
.|:.|....:....:||
Frog 1061 PDQANGPQGQQNQANGPQGQQNQANGPQGQQNQANGSRGEQNQANGSRGEQNQANGPQGQQNQEN 1125
Fly 1064 GT---ANSQKNPRLETVVDTQRGYKVDKNIAN-------------------------QSKMN--- 1097
|: .|....|:.:. :.:.|.:.::|.|| |::.|
Frog 1126 GSQGEQNQANGPQGQQ--NQENGSRGEQNQANGLQGQQNRTNGSRGQQNQENGLQGQQNRTNGSQ 1188
Fly 1098 -------------PNLKEIDAQNKARRNSTAHMDNLNPISNDPCQNNVNVKT---AQPIISNLND 1146
.|.:|..|..|.|....|...::.|.|..|......:.| :||.::....
Frog 1189 GQQNQANEPHLFDSNRREGPADPKLRPPHVAGRGHIRPQSEAPTGAEPTLATELLSQPTVAPKEP 1253
Fly 1147 IQK----QGSQIEKMKI---NPATVVCSPQLANEEKPSTSQSARRKLVNEG-MAERRRVALMKIQ 1203
..| .|..:.|::. ||..|.......::..||:..:.|:...:|| ::|..|.|....:
Frog 1254 PDKTMAAHGDSVPKLQTGAPNPTLVPPGGSNISDCLPSSCVTGRKVHPHEGQISEVPRRADSDPE 1318
Fly 1204 QRTQKENQSKD--------------QPIQASRSNQ--------------------LSSPVNRTPA 1234
|:....|||.| |||.:...|. .:.|.|:.|.
Frog 1319 QKCDSHNQSSDEVEEFPSMIMAIGEQPIVSGAVNSELRTGGTEPGGSTSPEIGLVQNQPPNKIPT 1383
Fly 1235 NRWT-QSEN-------------------PNNEMNNSQLPRRN---PRNQSPVPNANRTASRKV-S 1275
:..| ||.: ||.......:|.|. |..::.:|.:..:|...| |
Frog 1384 DPVTVQSVSSGSSHRARGGTASAISLLLPNGAPMRDPVPARTLGAPSAKTHIPQSTGSADLSVAS 1448
Fly 1276 NAEEDLFMADDS----FMLNTG---------------------------LAAALT----AAESKI 1305
...||.|..|.. ...||| :|.|.| .:|.|.
Frog 1449 KTFEDSFQLDTQTEKLIQQNTGTRPIGPHGNVEQEAKVDGDLKMEISEHVAIAPTGKNLVSEVKN 1513
Fly 1306 AS-----CTEADVIPSSQPKEPEVIGALTPHASRLKRSDQLRS---------------------- 1343
.| |::..::..||...|.|:. ..|........||:|
Frog 1514 ESPTENFCSQESMLFGSQEVPPVVVA--PEHRESSLTDTQLQSFFQAFPTQAPREQPGVSLHTPL 1576
Fly 1344 QRIQSPSPTPQREIEIDL----------------------ESKNESNGVSSMEISDMSMENPLMK 1386
.|.|||.|......|..| |.|..:.|...:...:...|.|..|
Frog 1577 PRAQSPVPVRDHRFETSLNMSDSFLFDSFTDDPEVEPKEEEPKRPTEGAEPVAGPETLSEPPSDK 1641
Fly 1387 NP-------LHLNASHIMSCSKVDETASSFSSIDIIDVCGHRNAFQAAIIEIN------------ 1432
|. |.||.:..::.|::| ||..::::|.....::....::::|
Frog 1642 NTIESQEPNLALNCNRSITFSQLD----SFQIVEVLDNAEEPSSPCRNVVQVNPSNQPDRGNEEQ 1702
Fly 1433 ----------------NATRLGFSVGLQ--------------------AQAGK-----QKPLIG- 1455
:.|....|.||| ..||| |:.|:.
Frog 1703 SGDPEKVEERISLLEWSDTSFNLSPGLQDVLDQWPSPSGNVTRRTSSMKAAGKESLPHQEKLVAS 1767
Fly 1456 -----SNL--------------------------------------LINQVAAAENR-------- 1469
||| |:.....||::
Frog 1768 QRGPESNLELLENNRSFLDGSCLNSTPVALPGNKRDSGSRPGSRTDLVPPTPPAESQPGRLVGVS 1832
Fly 1470 ---EAAARER---------VLFQVD-------------------------DTNFIS--------- 1488
.||.|.| :..::| ||:.|.
Frog 1833 SILSAAKRPRGESVGSATWLALEMDGDWSDPQAEGSDLGPRAFPGSECARDTSAIDEGFTLQLSQ 1897
Fly 1489 ----------------------------------------------------------------- 1488
Frog 1898 DGATAFPCSSGGFTIIDVASDQSLFRTFLREWSGQRRFSLCVACERRKQPPSSDAGIGGRFKQVR 1962
Fly 1489 -----------------------GVSFCLADNVAYYWNMQIDERAAYQGVPTPLKVQELCNLMAR 1530
|::.|.....|||.::|.::..| ::|..:|.
Frog 1963 GPQRPKVLEDGLPIKGMDDVLLVGLAVCWGGKDAYYISLQKEQDQA-----------DICPSLAP 2016
Fly 1531 KDL---------------------------TLVMHDGKEQLKMLRKAIPQLKRIS--AKLEDAKV 1566
..| |::|:|..||.|.|..|. |:| ...:|.||
Frog 2017 PPLDQTLSVKDRLWHIQSALQQIRPGGSEPTIIMYDCIEQYKALLLAC----RVSLAGHFQDPKV 2077
Fly 1567 ANWLLQP---DKTVNFLNMCQTFAPECTGLANLCGSGRGYSSYGLDTSSAILPRIRTAIESCV-- 1626
|.|||.| ::|:: ||...|.|....|.:..|.|:|..|.||..||....|.|.|||:.|
Frog 2078 ACWLLDPGSKERTLH--NMVTNFLPYELPLLDGVGPGQGVQSLGLSPSSDQTGRYRAAIEAVVVF 2140
Fly 1627 -TLHILQGQTENLSRIGNGDLLKFFHDIEMPIQLTLCQMELVGFPAQKQRLQQLYQRMVAVMKKV 1690
|::.|....| ...|...||.:|||.|..|..:||.|.....:..:.....|.|.:.::
Frog 2141 STMNALGALLE------KEKLQDAFHRVEMPTQYCLALLELNGMGFSTEECETQKHIMEAKLNEI 2199
Fly 1691 ETKIYEQHGSRFNLGSSQAVAKVLGLH--------RKAKG----------------------RVT 1725
|...|:..|..|:|.|...:|:||.|. .||:| :.:
Frog 2200 EAVAYQLAGRSFSLTSHDDLAQVLFLELKLPPNGDPKAQGNKKTLGYTRRAAASGARVRLGKQFS 2264
Fly 1726 TSRQVLEKLNS--PISHLILGYRKLSGLLAKSIQPL-----------MECCQADRIHGQSITYTA 1777
|::.|||||.: |:..|||.:::::..|.|.:.|| || ||:..|.|:||
Frog 2265 TAKDVLEKLKALHPLPGLILEWKRITNALTKVVFPLQREKLLNPNLGME-----RIYPISQTHTA 2324
Fly 1778 TGRISMTEPNLQNVAKEFSIQV--------------------------------GSDV------- 1803
|||:|.||||:|||.|:|.|:: |..|
Frog 2325 TGRVSFTEPNIQNVPKDFEIEMPRLVGESPPSQAPGPSAYPYRNRGKKPQVNTPGPKVPVEQIPA 2389
Fly 1804 -----VHISCRSPFMPTDESRCLLSADFCQLEMRILAHMSQDKALLEVMKSSQDLFIAIAAHWNK 1863
..:|.|..|:|. ....:|:||:.|||:|||||:|:|:.|::|:.|..|:|.:|||.|..
Frog 2390 ERGVSFFVSMRHAFVPF-PGGLILAADYSQLELRILAHLSRDRRLIQVLNSGSDVFKSIAAEWKM 2453
Fly 1864 IEESEVTQDLRNSTKQVCYGIVYGMGMRSLAESLNCSEQEARMISDQFHQAYKGIRDYTTRVVNF 1928
|:...||..:|...||:||||:||||.:||.|.:...|.:|....|.|...|.||:.:....|..
Frog 2454 IDPEAVTDTVRQQAKQICYGIIYGMGAKSLGEQMGIEESDAACYIDTFKSRYTGIQKFLKETVRS 2518
Fly 1929 ARSKGFVETITGRRRYLENINSDVEHLKNQAERQAVNSTIQGSAADIAKNAILKMEKNIE----- 1988
....|||:||.||||||..|.....:.|:.|||||||:|:|||||||.|.|.:.::|.:|
Frog 2519 CTRDGFVQTILGRRRYLPAIKDSNPYAKSHAERQAVNTTVQGSAADIVKTATVNIQKRLEETFPS 2583
Fly 1989 --------------------RYREKLALGDNSVDLVMHLHDELIFEVPTGKAKKIAKVLSLTMEN 2033
|:|.....| ...::.|||||::|.....|.::|:::...|||
Frog 2584 VPKSHEHPVQAGGTGRAERLRHRPPPTRG---AFFILQLHDELLYEAAQEDAIQVAQIIKKEMEN 2645
Fly 2034 CVKLSVPLKVKLRIGRSWGEFKE 2056
.:||||.|:||:::|.|||:.::
Frog 2646 AMKLSVKLRVKVKMGPSWGDLQD 2668
| 
