Protein Alignment DNApol-theta and Mtr4

DIOPT Version :9

• Sequence 1: NP_524333.1
• Gene: DNApol-theta / 41571
• FlyBaseID: FBgn0002905
• Length: 2059
• Species: Drosophila melanogaster
• Sequence 2: NP_524929.1
• Gene: Mtr4 / 48782
• FlyBaseID: FBgn0001986
• Length: 1055
• Species: Drosophila melanogaster
• Alignment Length: 1053
• Identity: 228/1053 - (21%)
• Similarity: 393/1053 - (37%)
• Gaps: 279/1053 - (26%)

  Fly    48 EIQEINSEFFRDEFSYEV-----NQAHKPAEQSVVNVSQVQQHMAVVSNQDSEDQSRSSALNDQI 107
            :|:|:...|  ||.:..|     ||..||:..|             .|.:.::.|:..:..:.:.
  Fly     2 DIEELFDCF--DEVTPSVPPPALNQEEKPSGSS-------------ASKKGNKRQADGTTASKEA 51

  Fly   108 CTQSSFEGEDAG---------------ADAVLDQPNLDENSFLCPAQDEEAS-EQLKEDILHSHS 156
            .:....||:|.|               ..||.|..|.|:........|:.|: |.|:..|: :|.
  Fly    52 TSSKGAEGDDKGDVTEEPTKRLKQEASTVAVDDDNNADDEPTRTLDIDDSATLEALRTRIV-THL 115

  Fly   157 VLAKQEFYQEISQVTQNLSSMSPNQLRVSPNSSRIREAMPERPAMPLDLNTLRSISAWNLPMSIQ 221
            :.|.:....|::                         |.|::..:|  |.....:.|...|.
  Fly   116 LDAPKSCTHEVA-------------------------AHPDQEYIP--LKPFSGVPAKEYPF--- 150

  Fly   222 AEYKKKGVVDMFDWQ-VECLSKPRLLFEHCNLVYSAPTSAGKTLVSEILMLKTVLERGKKVLLIL 285
                   |:|.|..| :.|:...:      :::.||.||||||:|:|..:.|::..: ::|:...
  Fly   151 -------VLDPFQRQAILCIDNSQ------SVLVSAHTSAGKTVVAEYAIAKSLAAK-QRVIYTT 201

  Fly   286 PFISVVREKMFYMQDLLTPAGYRVEGFYGGYTPPGGFESLHVAICTIEKANSIVNKLMEQGK--L 348
            |..::..:|.....|.....|...           |..:::.:...:.....|:..::.:|.  :
  Fly   202 PIKALSNQKFREFTDEFKDVGLVT-----------GDVTINPSASCLIMTTEILRNMLYRGSEIM 255

  Fly   349 ETIGMVVVDEVHLISDKGRGYILELLLAKILYMSRRNGLQIQVITMSATLENVQLLQSWL----- 408
            ..:|.||.||:|.:.||.||.:.|..|  ||...     .::.:.:|||:.|.:....|:
  Fly   256 REVGWVVFDEIHYMRDKERGVVWEETL--ILLPD-----NVRYVFLSATIPNARQFAEWVCHLHK 313

  Fly   409 -DAELYITNYRPVALKEMI-KVG----TVIYDHRLKLVRD--VAKQKVL---------------- 449
             ...:..|:|||..|:..| ..|    .:|.|.:.:...|  .....||
  Fly   314 QPCHVVYTDYRPTPLQHYIFPAGGDGIHLIVDEKGQFKEDNFTTAMAVLANAGEAGKGDQKGRHG 378

  Fly   450 -LKGLENDSDDVALLCIETLLEG--CSVIVFCPSKDWCENLAVQLATAIHVQIKSETVLGQRLRT 511
             :||......::..: ::.::|.  ..||:|..||..||..|:|:|     ::...|...::|..
  Fly   379 GIKGTNAGQTNIFKI-VKMIMERNFAPVIIFSFSKKDCEIYAMQMA-----KLDFNTPDEKKLVD 437

  Fly   512 NLNPRAIAEVKQQLRDIPTGLDGVMSKAITYACAFHHAGLTTEERDIIEASFKAGALKVLVATST 576
            .:...|:..:.::.|.:|. ::.|: ..:......||.||....::.||..|..|.:|.|.||.|
  Fly   438 EVFNNAMDVLTEEDRRLPQ-VENVL-PLLRRGIGIHHGGLLPILKETIEILFGEGLIKALFATET 500

  Fly   577 LSSGVNLPARRVLIRSP-LFGGKQ---MSSLTYRQMIGRAGRMGKDTLGESILICNE-INARMGR 636
            .:.|:|:|||.||..:| .|.||:   :||..|.||.|||||.|.|..|..||:.:| ::..:||
  Fly   501 FAMGLNMPARTVLFTAPRKFDGKKFRWISSGEYIQMAGRAGRRGLDDKGIVILMIDEKVSPAVGR 565

  Fly   637 DLVVSELQPITSCLDMDGSTHLKRALLEVISSGVANTKEDIDFFVNCTLLSAQKAFHAKEKPPDE 701
            |:|..:..||.|...:..:..|....:|.|:......:.    |......:|....|.:.:....
  Fly   566 DIVQGKADPINSAFHLTYNMVLNLLRVEEINPEYMLERS----FYQFQNQAALPGLHDQVEQKTL 626

  Fly   702 ESDANYINDALDFLVEYEFVRLQRNEERE-------TAVYVATRLGAACL----ASSMPPTDGLI 755
            |.:...|.|..: :..|..:|.|.::..:       ...|:...|....|    |.|.....|::
  Fly   627 ELNKLTIKDEHN-IASYHHIRSQLDQHGKQFRQWITKPQYLLPFLQPGRLVKVAAGSQEYDWGIV 690

  Fly   756 L-FAELQKSRRSFVLESELHAVYLVTPYSVCYQLQDIDWLLYVHMWEKLSSPMKKVG-------- 811
            | |.:..:||:     :.|.|...||          ||.||:|      |....|.|
  Fly   691 LNFKKQDQSRK-----NPLKAEPSVT----------IDVLLHV------SEAAAKTGDTEPCKPN 734

  Fly   812 -----ELVGVRDAFLYKALRGQTKLDYKQMQIHK-RFYIALALEELVNETPINVVVHKYKCHRGM 870
                 |:|.|....:              .||.. |.|....|....|             .|.:
  Fly   735 ERGCMEVVPVAHTLI--------------TQISSIRVYFPNDLRSADN-------------RRAV 772

  Fly   871 LQSLQQMASTFAGIVTAFCNSL--------QWSTLALIVSQFKDRL----------FFGIHR--- 914
            |:::|:....|. :.....|.:        ::..:...:|||:.||          ...|||
  Fly   773 LKTIQEAKKRFP-LGPPVLNPIDDMNIKDREFRDIVNTISQFEKRLEEHPLHKSPELERIHRRYQ 836

  Fly   915 DLIDLMR-IPDLSQ--KRARAL--------------------------FDAGITSLVELAGADPV 950
            |.:.|.: :.||..  |.||:|                          |...:.  .||:.||.:
  Fly   837 DKVTLQKQLQDLKAELKAARSLLQMDELKHRKRVLRRMGYCKPGDVIEFKGRVA--CELSSADEL 899

  Fly   951 ELEKVLYNSISFD 963
            .:.::::|.:..|
  Fly   900 LMTEMIFNGVFND 912

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNApol-theta	NP_524333.1	BRR2	209..978	CDD:224125	194/871 (22%)
		DEAD	251..404	CDD:278688	37/154 (24%)
		HELICc	542..616	CDD:197757	34/77 (44%)
		PolA	1489..2055	CDD:223820
		DNA_pol_A_theta	1668..2053	CDD:176475
Mtr4	NP_524929.1	Dob10	91..1055	CDD:226947	206/949 (22%)
		DEAD	154..299	CDD:278688	39/169 (23%)
		HELICc	390..554	CDD:238034	55/171 (32%)
		rRNA_proc-arch	600..853	CDD:289976	57/306 (19%)
		DSHCT	881..1048	CDD:285374	7/34 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466309
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840